YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|115345879, gi...
Organism:	Yersinia pestis CO92
Length:	151 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|115345879, gi....

Description	E-value	Query Range	Subject Range
gi\|77958458 - gi\|77958458\|ref\|ZP_00822491.1\| COG0756: dUTPase [Yersinia bercovieri ATCC 43970]	4.0E-52	[1..151]	[2..152]
gi\|21956756, gi\|... - gi\|22124014\|ref\|NP_667437.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pestis KIM],... gi\|45439913, gi\|... - gi\|45439913\|ref\|NP_991452.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pestis biova...	4.0E-52	[1..151]	[6..156]
gi\|108813963, gi... - gi\|108813963\|ref\|YP_649730.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pestis Nepa... gi\|108809486, gi... - gi\|108809486\|ref\|YP_653402.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pestis Anti... gi\|145212794, gi... - gi\|145601098\|ref\|YP_001165174.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pestis P... gi\|89103897 - gi\|89103897\|ref\|ZP_01176457.1\| COG0756: dUTPase [Yersinia pestis biovar Orientalis str. IP275] gi\|77634074 - gi\|77634074\|ref\|ZP_00796183.1\| COG0756: dUTPase [Yersinia pestis Angola] gi\|170026364, gi... - gi\|170026364\|ref\|YP_001722869.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pseudotu... gi\|117671896, gi... - gi\|77630875\|ref\|ZP_00793461.1\| COG0756: dUTPase [Yersinia pseudotuberculosis IP 31758], gi\|117671896... gi\|186893390, gi... - gi\|186893390\|ref\|YP_001870502.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pseudotu...	5.0E-52	[1..151]	[2..152]
gi\|77961979 - gi\|77961979\|ref\|ZP_00825806.1\| COG0756: dUTPase [Yersinia mollaretii ATCC 43969]	8.0E-52	[1..151]	[2..152]
DUT_HAEI8 - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Haemophilus influenzae (strain 86-028NP) GN=dut ... gi\|145274548, gi... - gi\|145640622\|ref\|ZP_01796205.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Haemophilus influe... DUT_HAEIG - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Haemophilus influenzae (strain PittGG) GN=dut PE... DUT_HAEIE - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Haemophilus influenzae (strain PittEE) GN=dut PE... gi\|42631278 - gi\|42631278\|ref\|ZP_00156816.1\| COG0756: dUTPase [Haemophilus influenzae R2866] gi\|145640622 - gi\|145640622\|ref\|ZP_01796205.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Haemophilus influe... DUT_HAEIN - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Haemophilus influenzae (strain ATCC 51907 / DSM ... gi\|145272552, gi... - gi\|145638223\|ref\|ZP_01793833.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Haemophilus influe... gi\|229811018, gi... - gi\|229846014\|ref\|ZP_04466126.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Haemophilus influe... gi\|145269511, gi... - gi\|145637259\|ref\|ZP_01792920.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Haemophilus influe... DUT_HAEIN - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Haemophilus influenzae GN=dut PE=3 SV=1	9.0E-52	[1..151]	[1..151]
gi\|77972441 - gi\|77972441\|ref\|ZP_00828007.1\| COG0756: dUTPase [Yersinia frederiksenii ATCC 33641]	1.0E-51	[1..151]	[2..152]
gi\|46129100 - gi\|46129100\|ref\|ZP_00155752.2\| COG0756: dUTPase [Haemophilus influenzae R2846]	4.0E-51	[1..151]	[1..151]
DUT_ECOK1 - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Escherichia coli O1:K1 / APEC GN=dut PE=3 SV=1 gi\|237703411, gi... - gi\|237703411\|ref\|ZP_04533892.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Escherichia sp. 3_... DUT_ECOUT - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Escherichia coli (strain UTI89 / UPEC) GN=dut PE...	6.0E-51	[1..151]	[2..152]
gi\|254795595, gi... - gi\|254795595\|ref\|YP_003080432.1\| deoxyuridinetriphosphatase [Escherichia coli O157:H7 str. TW14359],... gi\|253975469, gi... - gi\|254163568\|ref\|YP_003046676.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Escherichia coli ... gi\|254290318, gi... - gi\|254290318\|ref\|YP_003056066.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Escherichia coli ... gi\|15833769, gi\|... - gi\|15833769\|ref\|NP_312542.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Escherichia coli O157... sp\|B7UM46\|DUT_ECO27 - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC... gi\|209754622, gi... - pir\|\|D86040 deoxyuridinetriphosphatase [imported] - Escherichia coli (strain O157:H7, substrain EDL... DUT_SHIDS - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Shigella dysenteriae serotype 1 (strain Sd197) G... DUT_SHIBS - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Shigella boydii serotype 4 (strain Sb227) GN=dut... gi\|187775653, gi... - gi\|187775653\|ref\|ZP_02797401.2\| dUTP diphosphatase [Escherichia coli O157:H7 str. EC4196], gi\|187771... gi\|188024741, gi... - gi\|188024741\|ref\|ZP_02773734.2\| dUTP diphosphatase [Escherichia coli O157:H7 str. EC4113], gi\|188016... gi\|188491507, gi... - gi\|188496308\|ref\|ZP_03003578.1\| dUTP diphosphatase [Escherichia coli 53638], gi\|188491507\|gb\|EDU6661... gi\|190909405, gi... - gi\|191170597\|ref\|ZP_03032150.1\| dUTP diphosphatase [Escherichia coli F11], gi\|190909405\|gb\|EDV68991.... DUT_SHIB3 - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Shigella boydii serotype 18 (strain CDC 3083-94 ... DUT_ECOHS - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Escherichia coli O9:H4 (strain HS) GN=dut PE=3 S... DUT_ECO24 - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Escherichia coli O139:H28 (strain E24377A / ETEC... DUT_ECOLU - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Escherichia coli O17:K52:H18 (strain UMN026 / Ex... DUT_ECO27 - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC... DUT_ESCF3 - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Escherichia fergusonii (strain ATCC 35469 / DSM ... DUT_ECO8A - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Escherichia coli O8 (strain IAI1) GN=dut PE=3 SV... DUT_ECO55 - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Escherichia coli (strain 55989 / EAEC) GN=dut PE... gi\|194411896, gi... - gi\|194430069\|ref\|ZP_03062574.1\| dUTP diphosphatase [Escherichia coli B171], gi\|194411896\|gb\|EDX28213... gi\|194425345, gi... - gi\|194435802\|ref\|ZP_03067905.1\| dUTP diphosphatase [Escherichia coli 101-1], gi\|194425345\|gb\|EDX4132... gi\|208812900, gi... - gi\|208812900\|ref\|ZP_03254229.1\| dUTP diphosphatase [Escherichia coli O157:H7 str. EC4045], gi\|208734... gi\|208820080, gi... - gi\|208820080\|ref\|ZP_03260400.1\| dUTP diphosphatase [Escherichia coli O157:H7 str. EC4042], gi\|208740... DUT_ECO57 - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Escherichia coli O157:H7 GN=dut PE=3 SV=1 gi\|15804181, gi\|... - gi\|15804181\|ref\|NP_290220.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Escherichia coli O157... DUT_ECOL6 - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Escherichia coli O6 GN=dut PE=3 SV=1 gi\|242379164, gi... - gi\|251786891\|ref\|YP_003001195.1\| hypothetical protein B21_03449 [Escherichia coli BL21], gi\|24237916... DUT_ECOL6 - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700...	6.0E-51	[1..151]	[1..151]
DUT_ECOL5 - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) ... gi\|124528981, gi... - gi\|124528981\|ref\|ZP_01700127.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase Dut [Escherichia co... gi\|168785516, gi... - gi\|189374472\|gb\|EDU92888.1\| dUTP diphosphatase [Escherichia coli O157:H7 str. EC869], gi\|168785516\|r... gi\|168766060, gi... - gi\|189364660\|gb\|EDU83079.1\| dUTP diphosphatase [Escherichia coli O157:H7 str. EC4486], gi\|168766060\|... DUT_ECOLC - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / ... gi\|168798585, gi... - gi\|189378842\|gb\|EDU97258.1\| dUTP diphosphatase [Escherichia coli O157:H7 str. EC508], gi\|168798585\|r... gi\|189010079, gi... - gi\|189010079\|ref\|ZP_02804802.2\| dUTP diphosphatase [Escherichia coli O157:H7 str. EC4076], gi\|189002... DUT_ECOSM - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=dut... gi\|208728916, gi... - gi\|208809115\|ref\|ZP_03251452.1\| dUTP diphosphatase [Escherichia coli O157:H7 str. EC4206], gi\|208728... gi\|195936201 - gi\|195936201\|ref\|ZP_03081583.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Escherichia coli O... gi\|227839086, gi... - gi\|227883808\|ref\|ZP_04001613.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Escherichia coli 8... gi\|253322563, gi... - gi\|253771519\|ref\|YP_003034350.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase Dut [Escherichia c... gi\|226838805, gi... - gi\|254038840\|ref\|ZP_04872892.1\| dUTP diphosphatase [Escherichia sp. 1_1_43], gi\|226838805\|gb\|EEH7083... gi\|75514298 - gi\|75514298\|ref\|ZP_00736606.1\| COG0756: dUTPase [Escherichia coli 53638] gi\|193063834, gi... - gi\|75258180\|ref\|ZP_00729628.1\| COG0756: dUTPase [Escherichia coli E22], gi\|193063834\|ref\|ZP_03044921... gi\|75242581 - gi\|75242581\|ref\|ZP_00726325.1\| COG0756: dUTPase [Escherichia coli F11] gi\|189369473, gi... - gi\|189369473\|gb\|EDU87889.1\| dUTP diphosphatase [Escherichia coli O157:H7 str. EC4501], gi\|168759737\|... gi\|193070397, gi... - gi\|75234798\|ref\|ZP_00719101.1\| COG0756: dUTPase [Escherichia coli E110019], gi\|193070397\|ref\|ZP_0305... gi\|168753464, gi... - gi\|189358911\|gb\|EDU77330.1\| dUTP diphosphatase [Escherichia coli O157:H7 str. EC4401], gi\|168753464\|... gi\|190902146, gi... - gi\|75229031\|ref\|ZP_00715615.1\| COG0756: dUTPase [Escherichia coli B7A], gi\|191167803\|ref\|ZP_03029609... gi\|75208689 - gi\|75208689\|ref\|ZP_00708986.1\| COG0756: dUTPase [Escherichia coli B171] gi\|75197542 - gi\|75197542\|ref\|ZP_00707612.1\| COG0756: dUTPase [Escherichia coli HS] gi\|75188398 - gi\|75188398\|ref\|ZP_00701665.1\| COG0756: dUTPase [Escherichia coli E24377A] gi\|75179727 - gi\|75179727\|ref\|ZP_00699714.1\| COG0756: dUTPase [Shigella boydii BS512] gi\|83588513 - gi\|83588513\|ref\|ZP_00927137.1\| COG0756: dUTPase [Escherichia coli 101-1] gi\|194420723, gi... - gi\|83571426\|ref\|ZP_00922866.1\| COG0756: dUTPase [Shigella dysenteriae 1012], gi\|194431268\|ref\|ZP_030... DUT_ECOSE - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Escherichia coli (strain SE11) GN=dut PE=3 SV=1 DUT_ECO5E - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) ... gi\|217324705, gi... - gi\|217324705\|ref\|ZP_03440789.1\| dUTP diphosphatase [Escherichia coli O157:H7 str. TW14588], gi\|21732... gi\|26110716, gi\|... - gi\|26250286\|ref\|NP_756326.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Escherichia coli CFT0...	7.0E-51	[1..151]	[2..152]

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Predicted Domain #1

Region A:
Residues: [1-151]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKIDIKILD PRVGNEFPLP TYATEGSAGL DLRACLDHAV ELQPGQTTLL PTGLAIHIGD  60
   61 SALAAVILPR SGLGHKHGIV LGNLVGLIDS DYQGQLMVSV WNRGQQPFTI EPGERIAQMV 120
  121 FVPVVQAEFN LVEDFTDSER GTGGFGHSGR Q

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	51.69897
Match:	1dudA
Description:	DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDE HYDROLASE (D-UTPASE) COMPLEXED WITH THE SUBSTRATE ANALOGUE DEOXYURIDINE 5'-DIPHOSPHATE (D-UDP)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nucleoside-triphosphate diphosphatase activity	5.64898078077484	bayes_pls_golite062009
dUTP diphosphatase activity	5.62861923551608	bayes_pls_golite062009
hydrolase activity	1.8120510491809	bayes_pls_golite062009
catalytic activity	1.71668532866244	bayes_pls_golite062009
binding	1.05588720719142	bayes_pls_golite062009
peroxisome proliferator activated receptor binding	1.01014631701573	bayes_pls_golite062009
pyrimidine deoxyribonucleotide binding	0.378438138772693	bayes_pls_golite062009
pyrimidine nucleotide binding	0.26077271033521	bayes_pls_golite062009
nucleotide binding	0.0227161300506727	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: