YRC Public Data Repository - Protein Structure Prediction

Protein:	EG13672
Organism:	Escherichia coli K-12
Length:	253 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EG13672.

Description	E-value	Query Range	Subject Range
gi\|157080075, gi... - gi\|75189831\|ref\|ZP_00703098.1\| COG3568: Metal-dependent hydrolase [Escherichia coli E24377A], gi\|157...	203.0	[0..1]	[253..1]
gi\|191174511, gi... - gi\|75236198\|ref\|ZP_00720315.1\| COG3568: Metal-dependent hydrolase [Escherichia coli F11], gi\|1911745... gi\|110640994, gi... - gi\|110640994\|ref\|YP_668722.1\| hypothetical protein ECP_0804 [Escherichia coli 536], gi\|110342586\|gb\|...	203.0	[0..1]	[253..1]
gi\|187429973, gi... - gi\|75178420\|ref\|ZP_00698474.1\| COG3568: Metal-dependent hydrolase [Shigella boydii BS512], gi\|187732...	203.0	[0..1]	[253..1]
gi\|253774207, gi... - gi\|254287681\|ref\|YP_003053429.1\| predicted DNase [Escherichia coli BL21(DE3)], gi\|253976988\|gb\|ACT42... gi\|242376582, gi... - gi\|251784309\|ref\|YP_002998613.1\| hypothetical protein B21_00774 [Escherichia coli BL21], gi\|24237658... gi\|124527009, gi... - gi\|124527009\|ref\|ZP_01698846.1\| Endonuclease/exonuclease/phosphatase [Escherichia coli B], gi\|124501... gi\|254160867, gi... - gi\|254160867\|ref\|YP_003043975.1\| predicted DNase [Escherichia coli B str. REL606], gi\|253972768\|gb\|A... gi\|188490316, gi... - gi\|75512793\|ref\|ZP_00735285.1\| COG3568: Metal-dependent hydrolase [Escherichia coli 53638], gi\|18849... gi\|157065945, gi... - gi\|75194941\|ref\|ZP_00705011.1\| COG3568: Metal-dependent hydrolase [Escherichia coli HS], gi\|15716026... gi\|194422683, gi... - gi\|83586093\|ref\|ZP_00924730.1\| COG3568: Metal-dependent hydrolase [Escherichia coli 101-1], gi\|19443... gi\|170020854, gi... - gi\|170020854\|ref\|YP_001725808.1\| endonuclease/exonuclease/phosphatase [Escherichia coli ATCC 8739], ...	203.0	[0..1]	[253..1]
gi\|115512096, gi... - gi\|117622972\|ref\|YP_851885.1\| metal-dependent hydrolase [Escherichia coli APEC O1], gi\|115512096\|gb\|...	202.0	[0..1]	[253..1]
gi\|81240285, gi\|... - gi\|82776137\|ref\|YP_402484.1\| hypothetical protein SDY_0813 [Shigella dysenteriae Sd197], gi\|81240285...	199.0	[0..1]	[253..1]
gi\|90584514, gi\|... - gi\|90584514\|ref\|ZP_01240233.1\| Endonuclease/exonuclease/phosphatase [Staphylococcus aureus subsp. au...	191.0	[0..1]	[253..1]
lcl\|NC_016856.1_... - [gene=ybhP] [protein=putative cytoplasmic protein] [protein_id=YP_005236536.1] [location=complement(... gi\|205352071, gi... - gi\|205352071\|ref\|YP_002225872.1\| hypothetical protein SG0792 [Salmonella enterica subsp. enterica se... gi\|206708053, gi... - gi\|207856250\|ref\|YP_002242901.1\| hypothetical protein SEN0759 [Salmonella enterica subsp. enterica s... gi\|199602813, gi... - gi\|200390368\|ref\|ZP_03216979.1\| endonuclease/exonuclease/phosphatase family protein [Salmonella ente... gi\|204929865, gi... - gi\|204929865\|ref\|ZP_03220886.1\| endonuclease/exonuclease/phosphatase family protein [Salmonella ente... gi\|197363010, gi... - gi\|197363010\|ref\|YP_002142647.1\| hypothetical protein SSPA1809 [Salmonella enterica subsp. enterica ... gi\|198243219, gi... - gi\|198243219\|ref\|YP_002214776.1\| endonuclease/exonuclease/phosphatase family protein [Salmonella ent... gi\|16419319, gi\|... - gi\|16764176\|ref\|NP_459791.1\| putative cytoplasmic protein [Salmonella typhimurium LT2], gi\|16419319\|... gi\|56128344, gi\|... - gi\|56414087\|ref\|YP_151162.1\| hypothetical protein SPA1940 [Salmonella enterica subsp. enterica serov... gi\|62179380, gi\|... - gi\|62179380\|ref\|YP_215797.1\| putative cytoplasmic protein [Salmonella enterica subsp. enterica serov... gi\|238913372 - gi\|238913372\|ref\|ZP_04657209.1\| hypothetical protein SentesTe_19906 [Salmonella enterica subsp. ente... gi\|194734200, gi... - gi\|194734200\|ref\|YP_002113904.1\| endonuclease/exonuclease/phosphatase family protein [Salmonella ent... gi\|197215171, gi... - gi\|197251468\|ref\|YP_002145768.1\| endonuclease/exonuclease/phosphatase family protein [Salmonella ent... gi\|194450151, gi... - gi\|194450151\|ref\|YP_002044841.1\| endonuclease/exonuclease/phosphatase family protein [Salmonella ent... gi\|194457831, gi... - gi\|194471467\|ref\|ZP_03077451.1\| endonuclease/exonuclease/phosphatase family protein [Salmonella ente... gi\|168820041, gi... - gi\|205343080\|gb\|EDZ29844.1\| endonuclease/exonuclease/phosphatase family protein [Salmonella enterica... gi\|194402042, gi... - gi\|194443379\|ref\|YP_002040048.1\| endonuclease/exonuclease/phosphatase family protein [Salmonella ent... gi\|168263689, gi... - gi\|205347702\|gb\|EDZ34333.1\| endonuclease/exonuclease/phosphatase family protein [Salmonella enterica... gi\|168466402, gi... - gi\|195630975\|gb\|EDX49561.1\| endonuclease/exonuclease/phosphatase family protein [Salmonella enterica... gi\|197290109, gi... - gi\|197290109\|gb\|EDY29466.1\| endonuclease/exonuclease/phosphatase family protein [Salmonella enterica... gi\|205339836, gi... - gi\|205339836\|gb\|EDZ26600.1\| endonuclease/exonuclease/phosphatase family protein [Salmonella enterica... gi\|205329612, gi... - gi\|205329612\|gb\|EDZ16376.1\| endonuclease/exonuclease/phosphatase family protein [Salmonella enterica... gi\|205334664, gi... - gi\|205334664\|gb\|EDZ21428.1\| endonuclease/exonuclease/phosphatase family protein [Salmonella enterica... gi\|161614949, gi... - gi\|161614949\|ref\|YP_001588914.1\| hypothetical protein SPAB_02703 [Salmonella enterica subsp. enteric... gi\|167550511, gi... - gi\|205324628\|gb\|EDZ12467.1\| endonuclease/exonuclease/phosphatase family protein [Salmonella enterica...	188.0	[0..1]	[253..1]
gi\|48728911, gi\|... - gi\|77461257\|ref\|YP_350764.1\| aminoacyl-tRNA hydrolase [Pseudomonas fluorescens Pf0-1], gi\|77385260\|g...	186.0	[0..5]	[253..18]
gi\|213586700 - gi\|213586700\|ref\|ZP_03368526.1\| hypothetical protein SentesTyph_37640 [Salmonella enterica subsp. en... gi\|16502027, gi\|... - gi\|25353375\|pir\|\|AB0599 conserved hypothetical protein ybhP [imported] - Salmonella enterica subsp. ... gi\|213647750 - gi\|213647750\|ref\|ZP_03377803.1\| hypothetical protein SentesTy_10972 [Salmonella enterica subsp. ente... gi\|213855118 - gi\|213855118\|ref\|ZP_03383358.1\| hypothetical protein SentesT_13982 [Salmonella enterica subsp. enter... gi\|214000528 - gi\|214000528\|ref\|ZP_03411263.1\| hypothetical protein Salmonellentericaenterica_07841 [Salmonella ent... gi\|29138124, gi\|... - gi\|29142493\|ref\|NP_805835.1\| hypothetical protein t2075 [Salmonella enterica subsp. enterica serovar... gi\|16759734 - gi\|16759734\|ref\|NP_455351.1\| hypothetical protein STY0848 [Salmonella enterica subsp. enterica serov... gi\|213161219 - gi\|213161219\|ref\|ZP_03346929.1\| hypothetical protein Salmoneentericaenterica_14750 [Salmonella enter...	186.0	[0..1]	[253..1]

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Predicted Domain #1

Region A:
Residues: [1-253]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPDQTQQFSF KVLTINIHKG FTAFNRRFIL PELRDAVRTV SADIVCLQEV MGAHEVHPLH  60
   61 VENWPDTSHY EFLADTMWSD FAYGRNAVYP EGHHGNAVLS RYPIEHYENR DVSVDGAEKR 120
  121 GVLYCRIVPP MTGKAIHVMC VHLGLREAHR QAQLAMLAEW VNELPDGEPV LVAGDFNDWR 180
  181 QKANHPLKVQ AGLDEIFTRA HGRPARTFPV QFPLLRLDRI YVKNASASAP TALPLRTWRH 240
  241 LSDHAPLSAE IHL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	45.0
Match:	1e9nA
Description:	DNA repair endonuclease Hap1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.13555370693179	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	1.0882299598512	bayes_pls_golite062009
hydrolase activity	0.958422547201991	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: