YRC Public Data Repository - Protein Structure Prediction

Protein:	GLPG_SALTI
Organism:	Salmonella enterica subsp. enterica serovar Typhi
Length:	276 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GLPG_SALTI.

Description	E-value	Query Range	Subject Range
GLPG_SALNS - Rhomboid protease GlpG OS=Salmonella newport (strain SL254) GN=glpG PE=3 SV=2 GLPG_SALTY - Rhomboid protease glpG OS=Salmonella typhimurium GN=glpG PE=3 SV=1 lcl\|NC_016856.1_... - [gene=glpG] [protein=intramembrane serine protease GlpG] [protein_id=YP_005239730.1] [location=compl... GLPG_SALG2 - Rhomboid protease GlpG OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) GN=glpG PE=3 SV=1 GLPG_SALTY - Rhomboid protease GlpG OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=glpG PE=3 ... GLPG_SALEP - Rhomboid protease GlpG OS=Salmonella enteritidis PT4 (strain P125109) GN=glpG PE=3 SV=1 gi\|197265408, gi... - gi\|197265408\|ref\|ZP_03165482.1\| glp regulon protein [Salmonella enterica subsp. enterica serovar Sai... GLPG_SALTY - Rhomboid protease glpG OS=Salmonella typhimurium GN=glpG PE=3 SV=1 GLPG_SALDC - Rhomboid protease GlpG OS=Salmonella dublin (strain CT_02021853) GN=glpG PE=3 SV=1 GLPG_SALHS - Rhomboid protease GlpG OS=Salmonella heidelberg (strain SL476) GN=glpG PE=3 SV=1	3.0E-60	[1..276]	[1..276]
GLPG_SALCH - Rhomboid protease glpG OS=Salmonella choleraesuis GN=glpG PE=3 SV=1 GLPG_SALCH - Rhomboid protease glpG OS=Salmonella choleraesuis GN=glpG PE=3 SV=1 GLPG_SALCH - Rhomboid protease GlpG OS=Salmonella choleraesuis (strain SC-B67) GN=glpG PE=3 SV=1	4.0E-60	[1..276]	[1..276]
GLPG_SALPA - Rhomboid protease GlpG OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=glpG PE=3 SV=1 GLPG_SALPA - Rhomboid protease glpG OS=Salmonella paratyphi A GN=glpG PE=3 SV=1 GLPG_SALPK - Rhomboid protease GlpG OS=Salmonella paratyphi A (strain AKU_12601) GN=glpG PE=3 SV=1	6.0E-60	[1..276]	[1..276]
gi\|75260288 - gi\|75260288\|ref\|ZP_00731556.1\| COG0705: Uncharacterized membrane protein (homolog of Drosophila rhom... gi\|75237025 - gi\|75237025\|ref\|ZP_00721081.1\| COG0705: Uncharacterized membrane protein (homolog of Drosophila rhom... gi\|75229567 - gi\|75229567\|ref\|ZP_00716110.1\| COG0705: Uncharacterized membrane protein (homolog of Drosophila rhom... GLPG_ECO55 - Rhomboid protease GlpG OS=Escherichia coli (strain 55989 / EAEC) GN=glpG PE=3 SV=1 gi\|75211790 - gi\|75211790\|ref\|ZP_00711854.1\| COG0705: Uncharacterized membrane protein (homolog of Drosophila rhom... GLPG_ECO24 - Rhomboid protease GlpG OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=glpG PE=3 SV=1 GLPG_ECOSE - Rhomboid protease GlpG OS=Escherichia coli (strain SE11) GN=glpG PE=3 SV=1 GLPG_ECO8A - Rhomboid protease GlpG OS=Escherichia coli O8 (strain IAI1) GN=glpG PE=3 SV=1	2.0E-58	[1..275]	[1..275]
gi\|83588712, gi\|... - gi\|83588712\|ref\|ZP_00927336.1\| COG0705: Uncharacterized membrane protein (homolog of Drosophila rhom... gi\|237703155, gi... - gi\|237703155\|ref\|ZP_04533636.1\| rhomboid protease glpG [Escherichia sp. 3_2_53FAA], gi\|226902419\|gb\|... GLPG_ECOHS - Rhomboid protease GlpG OS=Escherichia coli O9:H4 (strain HS) GN=glpG PE=3 SV=1 GLPG_ECOBW - Rhomboid protease GlpG OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=glpG PE=3 SV=1 gi\|75241486 - gi\|75241486\|ref\|ZP_00725331.1\| COG0705: Uncharacterized membrane protein (homolog of Drosophila rhom... gi\|251786673, gi... - gi\|251786673\|ref\|YP_003000977.1\| hypothetical protein B21_03227 [Escherichia coli BL21], gi\|24237894... gi\|85676618, gi\|... - gi\|89110587\|ref\|AP_004367.1\| predicted intramembrane serine protease [Escherichia coli str. K-12 sub... gi\|253322791, gi... - gi\|254290101\|ref\|YP_003055849.1\| predicted intramembrane serine protease [Escherichia coli BL21(DE3)... gi\|254038591, gi... - gi\|254038591\|ref\|ZP_04872647.1\| rhomboid protease glpG [Escherichia sp. 1_1_43], gi\|226839097\|gb\|EEH... gi\|254163351, gi... - gi\|254163351\|ref\|YP_003046459.1\| predicted intramembrane serine protease [Escherichia coli B str. RE... gi\|83571652 - gi\|83571652\|ref\|ZP_00923092.1\| COG0705: Uncharacterized membrane protein (homolog of Drosophila rhom... GLPG_ECODH - Rhomboid protease GlpG OS=Escherichia coli (strain K12 / DH10B) GN=glpG PE=3 SV=1 GLPG_ECOSM - Rhomboid protease GlpG OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=glpG PE=3 SV=1 GLPG_ECO27 - Rhomboid protease GlpG OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=glpG PE=3 SV=1 GLPG_ECO45 - Rhomboid protease GlpG OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=glpG PE=3 SV=1 GLPG_ECOLI - Protein glpG - Escherichia coli GLPG_ECOLU - Rhomboid protease GlpG OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=glpG PE=3 SV=1 GLPG_ECOLC - Rhomboid protease GlpG OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=glpG PE=3 SV=1 GLPG_ECOL6 - Rhomboid protease glpG OS=Escherichia coli O6 GN=glpG PE=3 SV=1 GLPG_ECOK1 - Rhomboid protease GlpG OS=Escherichia coli O1:K1 / APEC GN=glpG PE=3 SV=1 EG10397 - rhomboid intramembrane serine protease / Rhomboid intramembrane serine protease; complements the phe... gi\|124528196, gi... - gi\|124528196\|ref\|ZP_01699529.1\| Rhomboid family protein [Escherichia coli B], gi\|124500851\|gb\|EAY483... GLPG_ECOL6 - Rhomboid protease GlpG OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=glpG PE=3 S... EG10397 - rhomboid intramembrane serine protease / Rhomboid intramembrane serine protease; complements the phe... GLPG_ECOUT - Rhomboid protease GlpG OS=Escherichia coli (strain UTI89 / UPEC) GN=glpG PE=3 SV=1 GLPG_ECOL5 - Rhomboid protease GlpG OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=glpG PE=3 SV=1 sp\|B7UKC8\|GLPG_ECO27 - Rhomboid protease glpG OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=glpG PE=3 SV=1 gi\|227839437, gi... - gi\|227883558\|ref\|ZP_04001363.1\| intramembrane serine protease GlpG [Escherichia coli 83972], gi\|2278...	2.0E-58	[1..275]	[1..275]
GLPG_SHIBS - Rhomboid protease GlpG OS=Shigella boydii serotype 4 (strain Sb227) GN=glpG PE=3 SV=1	2.0E-58	[1..275]	[1..275]
gi\|15833521, gi\|... - gi\|15833521\|ref\|NP_312294.1\| intramembrane serine protease GlpG [Escherichia coli O157:H7 str. Sakai... gi\|208735831, gi... - gi\|208814554\|ref\|ZP_03255883.1\| peptidase, S54 (rhomboid) family [Escherichia coli O157:H7 str. EC40... gi\|208806161, gi... - gi\|208806161\|ref\|ZP_03248498.1\| peptidase, S54 (rhomboid) family [Escherichia coli O157:H7 str. EC42... GLPG_ECO5E - Rhomboid protease GlpG OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=glpG PE=3 SV=1 gi\|187775654, gi... - gi\|187775654\|ref\|ZP_02797687.2\| peptidase, S54 (rhomboid) family [Escherichia coli O157:H7 str. EC41... gi\|168797198, gi... - gi\|189379970\|gb\|EDU98386.1\| peptidase, S54 (rhomboid) family [Escherichia coli O157:H7 str. EC508], ... gi\|189402769, gi... - gi\|189402769\|ref\|ZP_02790782.2\| peptidase, S54 (rhomboid) family [Escherichia coli O157:H7 str. EC44... gi\|188018326, gi... - gi\|188024498\|ref\|ZP_02772117.2\| peptidase, S54 (rhomboid) family [Escherichia coli O157:H7 str. EC41... GLPG_ECO57 - Rhomboid protease GlpG OS=Escherichia coli O157:H7 GN=glpG PE=3 SV=1 gi\|168753180, gi... - gi\|189359206\|gb\|EDU77625.1\| peptidase, S54 (rhomboid) family [Escherichia coli O157:H7 str. EC4401],... gi\|209756338, gi... - pir\|\|D86008 protein of glp regulon [imported] - Escherichia coli (strain O157:H7, substrain EDL933)... gi\|168785232, gi... - gi\|189374373\|gb\|EDU92789.1\| peptidase, S54 (rhomboid) family [Escherichia coli O157:H7 str. EC869], ... gi\|15803931, gi\|... - gi\|15803931\|ref\|NP_289967.1\| intramembrane serine protease GlpG [Escherichia coli O157:H7 EDL933], g... gi\|189002278, gi... - gi\|189002278\|gb\|EDU71264.1\| peptidase, S54 (rhomboid) family [Escherichia coli O157:H7 str. EC4076],... GLPG_SHISS - Rhomboid protease GlpG OS=Shigella sonnei (strain Ss046) GN=glpG PE=3 SV=1 GLPG_SHIDS - Rhomboid protease GlpG OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=glpG PE=3 SV=1 gi\|254795341, gi... - gi\|254795341\|ref\|YP_003080178.1\| predicted intramembrane serine protease [Escherichia coli O157:H7 s...	4.0E-58	[1..275]	[1..275]
gi\|16131298\|ref\|... - GlpG [Escherichia coli K12], GlpG [Escherichia coli K12] gi\|7429008, gi\|1... - pir\|\|BVECGG glpG protein - Escherichia coli (strain K-12), gi\|1293533\|gb\|AAC28166.1\| the translation...	5.0E-58	[1..275]	[1..275]
GLPG_SHIB3 - Rhomboid protease GlpG OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=glpG PE=3 SV=1	7.0E-58	[1..275]	[1..275]

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Predicted Domain #1

Region A:
Residues: [1-82]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLMITSFANP RVAQAFVDYM ATQGVILTIQ QHNQSDIWLA DESQAERVRV ELARFIENPG  60
   61 DPRYLAASWQ SGQTNSGLRY RR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	12.30103
Match:	2gqcA
Description:	No description for 2gqcA was found.

Predicted Domain #2

Region A:
Residues: [83-276]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FPFLATLRER AGPVTWIVML ACVVVYIAMS LIGDQTVMVW LAWPFDPVLK FEVWRYFTHI  60
   61 FMHFSLMHIL FNLLWWWYLG GAVEKRLGSG KLIVITVISA LLSGYVQQKF SGPWFGGLSG 120
  121 VVYALMGYVW LRGERDPQSG IYLQRGLIIF ALLWIVAGWF DWFGMSMANG AHIAGLIVGL 180
  181 AMAFVDTLNA RKRT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	30.69897
Match:	2irvA
Description:	No description for 2irvA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits