YRC Public Data Repository - Protein Structure Prediction

Protein:	GLGA_SALTI
Organism:	Salmonella enterica subsp. enterica serovar Typhi
Length:	477 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GLGA_SALTI.

Description	E-value	Query Range	Subject Range
GLGA_SALTY - Glycogen synthase OS=Salmonella typhimurium GN=glgA PE=3 SV=2 GLGA_SALPB - Glycogen synthase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=glgA PE=3 SV=1 GLGA_SALPA - Glycogen synthase OS=Salmonella paratyphi A GN=glgA PE=3 SV=1 GLGA_SALPA - Glycogen synthase OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=glgA PE=3 SV=1 GLGA_SALTY - Glycogen synthase OS=Salmonella typhimurium GN=glgA PE=3 SV=2 gi\|205338838, gi... - gi\|205338838\|gb\|EDZ25602.1\| starch synthase [Salmonella enterica subsp. enterica serovar Heidelberg ... gi\|168260742, gi... - gi\|205350336\|gb\|EDZ36967.1\| starch synthase [Salmonella enterica subsp. enterica serovar Hadar str. ... gi\|168465191, gi... - gi\|195632314\|gb\|EDX50798.1\| starch synthase [Salmonella enterica subsp. enterica serovar Newport str... GLGA_SALNS - Glycogen synthase OS=Salmonella newport (strain SL254) GN=glgA PE=3 SV=1 gi\|167549255, gi... - gi\|205325827\|gb\|EDZ13666.1\| starch synthase [Salmonella enterica subsp. enterica serovar Saintpaul s... gi\|205330720, gi... - gi\|205330720\|gb\|EDZ17484.1\| starch synthase [Salmonella enterica subsp. enterica serovar 4,[5],12:i:... gi\|168232676, gi... - gi\|205333086\|gb\|EDZ19850.1\| starch synthase [Salmonella enterica subsp. enterica serovar Kentucky st... gi\|197291280, gi... - gi\|197291280\|gb\|EDY30632.1\| starch synthase [Salmonella enterica subsp. enterica serovar Schwarzengr... lcl\|NC_016856.1_... - [gene=glgA] [protein=glycogen synthase] [protein_id=YP_005239740.1] [location=complement(3715078..37... GLGA_SALTY - Glycogen synthase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=glgA PE=3 SV=2 GLGA_SALEP - Glycogen synthase OS=Salmonella enteritidis PT4 (strain P125109) GN=glgA PE=3 SV=1 GLGA_SALPB - Glycogen synthase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=glgA PE=3 SV=1 gi\|197243618, gi... - gi\|197265363\|ref\|ZP_03165437.1\| starch synthase [Salmonella enterica subsp. enterica serovar Saintpa... GLGA_SALPK - Glycogen synthase OS=Salmonella paratyphi A (strain AKU_12601) GN=glgA PE=3 SV=1 GLGA_SALDC - Glycogen synthase OS=Salmonella dublin (strain CT_02021853) GN=glgA PE=3 SV=1 gi\|204322205, gi... - gi\|204928772\|ref\|ZP_03219971.1\| starch synthase [Salmonella enterica subsp. enterica serovar Javiana... GLGA_SALHS - Glycogen synthase OS=Salmonella heidelberg (strain SL476) GN=glgA PE=3 SV=1 gi\|194469520, gi... - gi\|194469520\|ref\|ZP_03075504.1\| starch synthase [Salmonella enterica subsp. enterica serovar Kentuck... GLGA_SALSV - Glycogen synthase OS=Salmonella schwarzengrund (strain CVM19633) GN=glgA PE=3 SV=1 GLGA_SALA4 - Glycogen synthase OS=Salmonella agona (strain SL483) GN=glgA PE=3 SV=1	3.0E-92	[1..477]	[1..477]
GLGA_SALCH - Glycogen synthase OS=Salmonella choleraesuis (strain SC-B67) GN=glgA PE=3 SV=1 GLGA_SALPC - Glycogen synthase OS=Salmonella paratyphi C (strain RKS4594) GN=glgA PE=3 SV=1 GLGA_SALCH - Glycogen synthase OS=Salmonella choleraesuis GN=glgA PE=3 SV=1 GLGA_SALCH - Glycogen synthase OS=Salmonella choleraesuis GN=glgA PE=3 SV=1	3.0E-92	[1..477]	[1..477]
GLGA2_NITOC - Glycogen synthase 2 OS=Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848) GN=glgA2 PE=3 SV=1 gi\|207091072 - gi\|207091072\|gb\|EDZ68343.1\| glycogen/starch synthase, ADP-glucose type subfamily [Nitrosococcus ocea... gi\|254434739, gi... - gi\|254434739\|ref\|ZP_05048247.1\| glycogen/starch synthase, ADP-glucose type subfamily [Nitrosococcus ...	5.0E-91	[2..476]	[3..479]
gi\|77975072 - gi\|77975072\|ref\|ZP_00830609.1\| COG0297: Glycogen synthase [Yersinia frederiksenii ATCC 33641]	8.0E-91	[1..476]	[1..476]
GLGA_SHIF8 - Glycogen synthase OS=Shigella flexneri serotype 5b (strain 8401) GN=glgA PE=3 SV=1	1.0E-90	[1..477]	[1..477]
GLGA_SHISS - Glycogen synthase OS=Shigella sonnei (strain Ss046) GN=glgA PE=3 SV=1	1.0E-90	[1..477]	[1..477]
gi\|24114695, gi\|... - gi\|24114695\|ref\|NP_709205.1\| glycogen synthase [Shigella flexneri 2a str. 301], gi\|24053906\|gb\|AAN44... gi\|30065287, gi\|... - gi\|30065287\|ref\|NP_839458.1\| glycogen synthase [Shigella flexneri 2a str. 2457T], gi\|30043549\|gb\|AAP... GLGA_SHIFL - Glycogen synthase OS=Shigella flexneri GN=glgA PE=3 SV=1	1.0E-90	[1..477]	[1..477]
GLGA_SHIDS - Glycogen synthase OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=glgA PE=3 SV=1	2.0E-90	[1..477]	[1..477]
gi\|15833528, gi\|... - gi\|15833528\|ref\|NP_312301.1\| glycogen synthase [Escherichia coli O157:H7 str. Sakai], gi\|13363748\|db... GLGA_ECOL5 - Glycogen synthase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=glgA PE=3 SV=1 gi\|253975257, gi... - gi\|254163356\|ref\|YP_003046464.1\| glycogen synthase [Escherichia coli B str. REL606], gi\|253975257\|gb... gi\|226839102, gi... - gi\|254038596\|ref\|ZP_04872652.1\| starch synthase [Escherichia sp. 1_1_43], gi\|226839102\|gb\|EEH71125.1... gi\|254594748, gi... - gi\|254795348\|ref\|YP_003080185.1\| glycogen synthase [Escherichia coli O157:H7 str. TW14359], gi\|25459... GLGA_ECO81 - Glycogen synthase OS=Escherichia coli O81 (strain ED1a) GN=glgA PE=3 SV=1 GLGA_ECO55 - Glycogen synthase OS=Escherichia coli (strain 55989 / EAEC) GN=glgA PE=3 SV=1 GLGA_ECO7I - Glycogen synthase OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=glgA PE=3 SV=1 GLGA_ECOLU - Glycogen synthase OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=glgA PE=3 SV=1 GLGA_ECO27 - Glycogen synthase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=glgA PE=3 SV=1 gi\|217326057, gi... - gi\|217326057\|ref\|ZP_03442141.1\| starch synthase [Escherichia coli O157:H7 str. TW14588], gi\|21732227... GLGA_ECOLC - Glycogen synthase OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=glgA PE=3 SV=1 GLGA_ECO8A - Glycogen synthase OS=Escherichia coli O8 (strain IAI1) GN=glgA PE=3 SV=1 GLGA_ECO45 - Glycogen synthase OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=glgA PE=3 SV=1 gi\|208734257, gi... - gi\|208812980\|ref\|ZP_03254309.1\| starch synthase [Escherichia coli O157:H7 str. EC4045], gi\|208734257... gi\|208739689, gi... - gi\|208819566\|ref\|ZP_03259886.1\| starch synthase [Escherichia coli O157:H7 str. EC4042], gi\|208739689... GLGA_ECO5E - Glycogen synthase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=glgA PE=3 SV=1 GLGA_ECOSE - Glycogen synthase OS=Escherichia coli (strain SE11) GN=glgA PE=3 SV=1 EG10377 - glycogen synthase / Glycogen synthase GLGA_ECOLI - Glycogen synthase (EC 2.4.1.21) (Starch [bacterial glycogen] synthase) - Escherichia coli gi\|168747087, gi... - gi\|188018229\|gb\|EDU56351.1\| starch synthase [Escherichia coli O157:H7 str. EC4113], gi\|168747087\|ref... gi\|168753188, gi... - gi\|189358925\|gb\|EDU77344.1\| starch synthase [Escherichia coli O157:H7 str. EC4401], gi\|168753188\|ref... gi\|168759460, gi... - gi\|189369816\|gb\|EDU88232.1\| starch synthase [Escherichia coli O157:H7 str. EC4501], gi\|168759460\|ref... gi\|189364492, gi... - gi\|189364492\|gb\|EDU82911.1\| starch synthase [Escherichia coli O157:H7 str. EC4486], gi\|168765783\|ref... gi\|85676613, gi\|... - gi\|89110582\|ref\|AP_004362.1\| glycogen synthase [Escherichia coli str. K-12 substr. W3110], gi\|856766... sp\|B7UKD4\|GLGA_ECO27 - Glycogen synthase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=glgA PE=3 SV=1 gi\|194420681, gi... - gi\|194431226\|ref\|ZP_03063519.1\| starch synthase [Shigella dysenteriae 1012], gi\|194420681\|gb\|EDX3675... gi\|194435641, gi... - gi\|194435641\|ref\|ZP_03067744.1\| starch synthase [Escherichia coli 101-1], gi\|194425184\|gb\|EDX41168.1... gi\|195934921 - gi\|195934921\|ref\|ZP_03080303.1\| glycogen synthase [Escherichia coli O157:H7 str. EC4024] gi\|208726750, gi... - gi\|208806949\|ref\|ZP_03249286.1\| starch synthase [Escherichia coli O157:H7 str. EC4206], gi\|208726750... GLGA_ECOK1 - Glycogen synthase OS=Escherichia coli O1:K1 / APEC GN=glgA PE=3 SV=1 gi\|190908139, gi... - gi\|191171512\|ref\|ZP_03033060.1\| starch synthase [Escherichia coli F11], gi\|190908139\|gb\|EDV67730.1\| ... gi\|192932470, gi... - gi\|193061680\|ref\|ZP_03042777.1\| starch synthase [Escherichia coli E22], gi\|192932470\|gb\|EDV85067.1\| ... gi\|193068797, gi... - gi\|193068797\|ref\|ZP_03049757.1\| starch synthase [Escherichia coli E110019], gi\|192957873\|gb\|EDV88316... gi\|124500858, gi... - gi\|124528203\|ref\|ZP_01699536.1\| glycogen/starch synthases, ADP-glucose type [Escherichia coli B], gi... gi\|194427072, gi... - gi\|194427072\|ref\|ZP_03059624.1\| starch synthase [Escherichia coli B171], gi\|194415033\|gb\|EDX31303.1\|... GLGA_ECODH - Glycogen synthase OS=Escherichia coli (strain K12 / DH10B) GN=glgA PE=3 SV=1 GLGA_ECOSM - Glycogen synthase OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=glgA PE=3 SV=1 gi\|188489227, gi... - gi\|188494028\|ref\|ZP_03001298.1\| glycogen synthase [Escherichia coli 53638], gi\|188489227\|gb\|EDU64330... gi\|227839451, gi... - gi\|227883572\|ref\|ZP_04001377.1\| glycogen synthase [Escherichia coli 83972], gi\|227839451\|gb\|EEJ49917... gi\|191167290, gi... - gi\|191167290\|ref\|ZP_03029107.1\| starch synthase [Escherichia coli B7A], gi\|190902642\|gb\|EDV62374.1\| ... gi\|168772672, gi... - gi\|187771625\|gb\|EDU35469.1\| starch synthase [Escherichia coli O157:H7 str. EC4196], gi\|168772672\|ref... GLGA_ECOBW - Glycogen synthase OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=glgA PE=3 SV=1 gi\|189002633, gi... - gi\|189002633\|gb\|EDU71619.1\| starch synthase [Escherichia coli O157:H7 str. EC4076], gi\|168779519\|ref... gi\|237703169, gi... - gi\|237703169\|ref\|ZP_04533650.1\| starch synthase [Escherichia sp. 3_2_53FAA], gi\|226902433\|gb\|EEH8869... gi\|189374458, gi... - gi\|189374458\|gb\|EDU92874.1\| starch synthase [Escherichia coli O157:H7 str. EC869], gi\|168785240\|ref\|... gi\|254290106, gi... - gi\|254290106\|ref\|YP_003055854.1\| glycogen synthase [Escherichia coli BL21(DE3)], gi\|253979413\|gb\|ACT... gi\|168797206, gi... - gi\|189379954\|gb\|EDU98370.1\| starch synthase [Escherichia coli O157:H7 str. EC508], gi\|168797206\|ref\|... gi\|251786680, gi... - gi\|251786680\|ref\|YP_003000984.1\| hypothetical protein B21_03234 [Escherichia coli BL21], gi\|24237895... GLGA_ECOL6 - Glycogen synthase OS=Escherichia coli O6 GN=glgA PE=3 SV=1 GLGA_ECOHS - Glycogen synthase OS=Escherichia coli O9:H4 (strain HS) GN=glgA PE=3 SV=1 GLGA_ECO24 - Glycogen synthase OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=glgA PE=3 SV=1 GLGA_ECO57 - Glycogen synthase OS=Escherichia coli O157:H7 GN=glgA PE=3 SV=1 GLGA_ECOL6 - Glycogen synthase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=glgA PE=3 SV=1 gi\|15803938, gi\|... - gi\|15803938\|ref\|NP_289974.1\| glycogen synthase [Escherichia coli O157:H7 EDL933], gi\|12518073\|gb\|AAG... EG10377 - glycogen synthase / Glycogen synthase	2.0E-90	[1..477]	[1..477]
GLGA_SHIBS - Glycogen synthase OS=Shigella boydii serotype 4 (strain Sb227) GN=glgA PE=3 SV=1	2.0E-90	[1..477]	[1..477]

Back

Predicted Domain #1

Region A:
Residues: [1-477]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQVLHVCSEM FPLLKTGGLA DVIGALPAAQ IADGVDVRVL LPGFPDIRRG IPDAHVVSRR  60
   61 DTFAGKISLL FGHYNGVGIY LIDAPHLYER PGSPYHDTNL YAYIDNVLRF ALLGWVGCEM 120
  121 ACGLDPFWRP DVVHAHDWHA GLAPAYLAAR GRPAKSVFTV HNLAYQGMFY AKHMDDIELP 180
  181 WSFFNMHGLE FNGQLSFLKA GLYYADHITA VSPTYAREIT EPQFAYGMEG LLRQRHLEGR 240
  241 LSGILNGVDE KIWNPESDLL LASRYTRDTL EEKAENKRQL QIAMGLKVND KVPLFAVVSR 300
  301 LTNQKGLDLV LEALPGLLEQ GGQLALLGAG DPVLQEGFLA AAAEHPGQAG VQIGYHEAFS 360
  361 HRIMGGADVI LVPSRFEPCG LTQLYGLKYG TLPLVRRTGG LADTVSDSSL ENLADGIASG 420
  421 FVFEDSNAWS LLRAIRRAFV LWSRPSLWRF VQRQAMAMDF SWQVAAKSYR ELYYRLK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	79.0
Match:	1rzuA
Description:	Crystal structure of the glycogen synthase from A. tumefaciens in complex with ADP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
glycogen phosphorylase activity	3.34851380039572	bayes_pls_golite062009
transferase activity, transferring hexosyl groups	3.04530122157712	bayes_pls_golite062009
catalytic activity	3.02192459767177	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	2.94500176353224	bayes_pls_golite062009
phosphorylase activity	2.90311878311075	bayes_pls_golite062009
glycogen (starch) synthase activity	2.05207088363955	bayes_pls_golite062009
glucosyltransferase activity	1.8062586862583	bayes_pls_golite062009
transferase activity	1.67770954408305	bayes_pls_golite062009
UDP-N-acetylglucosamine 2-epimerase activity	1.63103907245982	bayes_pls_golite062009
lipopolysaccharide heptosyltransferase activity	1.555502709955	bayes_pls_golite062009
UDP-glucosyltransferase activity	1.4199532885636	bayes_pls_golite062009
UDP-glycosyltransferase activity	1.30934991061674	bayes_pls_golite062009
starch synthase activity	1.073959209177	bayes_pls_golite062009
racemase and epimerase activity, acting on carbohydrates and derivatives	0.27693350081385	bayes_pls_golite062009
alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity	0.22009679964126	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: