YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|29144166, gi\|...
Organism:	Salmonella enterica subsp. enterica serovar Typhi str. Ty2
Length:	559 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|29144166, gi|....

Description	E-value	Query Range	Subject Range
gi\|56415525, gi\|... - gi\|56415525\|ref\|YP_152600.1\| hypothetical protein SPA3480 [Salmonella enterica subsp. enterica serov... gi\|197364451, gi... - gi\|197364451\|ref\|YP_002144088.1\| hypothetical protein SSPA3249 [Salmonella enterica subsp. enterica ...	0.0	[1..559]	[1..559]
gi\|82545902, gi\|... - gi\|82545902\|ref\|YP_409849.1\| hypothetical protein SBO_3537 [Shigella boydii Sb227], gi\|81247313\|gb\|A...	0.0	[1..559]	[1..559]
gi\|157080019, gi... - gi\|157157989\|ref\|YP_001465008.1\| hypothetical protein EcE24377A_4026 [Escherichia coli E24377A], gi\|... gi\|188018321, gi... - gi\|188018321\|gb\|EDU56443.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4113], g... gi\|168759622, gi... - gi\|189369617\|gb\|EDU88033.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501], g... gi\|189359388, gi... - gi\|189359388\|gb\|EDU77807.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4401], g... gi\|168772508, gi... - gi\|187771369\|gb\|EDU35213.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4196], g... gi\|168765945, gi... - gi\|189364388\|gb\|EDU82807.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4486], g... gi\|15833672, gi\|... - gi\|15833672\|ref\|NP_312445.1\| hypothetical protein ECs4418 [Escherichia coli O157:H7 str. Sakai], gi\|... gi\|25339912, gi\|... - pir\|\|B91181 hypothetical protein ECs4418 [imported] - Escherichia coli (strain O157:H7, substrain R... gi\|15833672, gi\|... - gi\|15833672\|ref\|NP_312445.1\| hypothetical protein ECs4418 [Escherichia coli O157:H7], gi\|13363892\|db... gi\|218556089, gi... - gi\|218556089\|ref\|YP_002389002.1\| putative endoglucanase involved in cellulose biosynthesis [Escheric... gi\|217324849, gi... - gi\|217324849\|ref\|ZP_03440933.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. TW1458... gi\|218697248, gi... - gi\|218697248\|ref\|YP_002404915.1\| putative endoglucanase involved in cellulose biosynthesis [Escheric... gi\|254795491, gi... - gi\|254795491\|ref\|YP_003080328.1\| predicted inner membrane protein [Escherichia coli O157:H7 str. TW1... gi\|189379884, gi... - gi\|189379884\|gb\|EDU98300.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC508], gi... gi\|168779681, gi... - gi\|189002256\|gb\|EDU71242.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4076], g... gi\|208729201, gi... - gi\|208809400\|ref\|ZP_03251737.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4206... gi\|195935065 - gi\|195935065\|ref\|ZP_03080447.1\| hypothetical protein EscherichcoliO157_01185 [Escherichia coli O157:... gi\|208820643, gi... - gi\|208820643\|ref\|ZP_03260963.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4042... gi\|208813017, gi... - gi\|208813017\|ref\|ZP_03254346.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4045... gi\|193061733, gi... - gi\|75260177\|ref\|ZP_00731445.1\| hypothetical protein EcolE2_01000064 [Escherichia coli E22], gi\|19306... gi\|209914257, gi... - gi\|209920998\|ref\|YP_002295082.1\| hypothetical protein ECSE_3807 [Escherichia coli SE11], gi\|20991425... gi\|191165226, gi... - gi\|75231616\|ref\|ZP_00717974.1\| hypothetical protein EcolB7_01000300 [Escherichia coli B7A], gi\|19116... gi\|209159932, gi... - gi\|209398532\|ref\|YP_002273018.1\| hypothetical protein ECH74115_4904 [Escherichia coli O157:H7 str. E...	0.0	[1..559]	[1..559]
gi\|194428705, gi... - gi\|75210084\|ref\|ZP_00710263.1\| hypothetical protein EcolB_01002765 [Escherichia coli B171], gi\|19442...	0.0	[1..559]	[1..559]
gi\|110616916, gi... - gi\|110807368\|ref\|YP_690888.1\| hypothetical protein SFV_3549 [Shigella flexneri 5 str. 8401], gi\|1106...	0.0	[1..559]	[1..559]
gi\|74314209, gi\|... - gi\|74314209\|ref\|YP_312628.1\| hypothetical protein SSON_3852 [Shigella sonnei Ss046], gi\|73857686\|gb\|...	0.0	[1..559]	[1..559]
YHJU_ECOLI - Hypothetical protein yhjU - Escherichia coli gi\|238902626, gi... - gi\|238902626\|ref\|YP_002928422.1\| putative inner membrane protein [Escherichia coli BW2952], gi\|23886... gi\|251786783, gi... - gi\|251786783\|ref\|YP_003001087.1\| hypothetical protein B21_03339 [Escherichia coli BL21], gi\|24237905... gi\|253771631, gi... - gi\|254290209\|ref\|YP_003055957.1\| predicted inner membrane protein [Escherichia coli BL21(DE3)], gi\|2... gi\|254163459, gi... - gi\|254163459\|ref\|YP_003046567.1\| predicted inner membrane protein [Escherichia coli B str. REL606], ... gi\|83588607, gi\|... - gi\|83588607\|ref\|ZP_00927231.1\| hypothetical protein Ecol1_01000239 [Escherichia coli 101-1], gi\|1944... gi\|169890881, gi... - gi\|170083046\|ref\|YP_001732366.1\| inner membrane protein [Escherichia coli str. K-12 substr. DH10B], ... gi\|188493431, gi... - gi\|75516001\|ref\|ZP_00738119.1\| hypothetical protein Ecol5_01000060 [Escherichia coli 53638], gi\|1884... EG12265 - DUF3260 family cellulose production inner membrane protein / DUF3260 family inner membrane protein; ... gi\|85676507, gi\|... - gi\|89110476\|ref\|AP_004256.1\| predicted inner membrane protein [Escherichia coli str. K-12 substr. W3... EG12265 - DUF3260 family cellulose production inner membrane protein / DUF3260 family inner membrane protein; ...	0.0	[1..559]	[1..559]
gi\|24114804, gi\|... - gi\|24114804\|ref\|NP_709314.1\| hypothetical protein SF3570 [Shigella flexneri 2a str. 301], gi\|2405403... gi\|30043444, gi\|... - gi\|30065182\|ref\|NP_839353.1\| hypothetical protein S4197 [Shigella flexneri 2a str. 2457T], gi\|300434...	0.0	[1..559]	[1..559]
gi\|15804080, gi\|... - gi\|15804080\|ref\|NP_290118.1\| hypothetical protein Z4954 [Escherichia coli O157:H7 EDL933], gi\|125182... gi\|25339914 - pir\|\|E86027 hypothetical protein yhjU [imported] - Escherichia coli (strain O157:H7, substrain EDL9...	0.0	[1..559]	[1..559]
gi\|26250172, gi\|... - gi\|26250172\|ref\|NP_756212.1\| hypothetical protein c4350 [Escherichia coli CFT073], gi\|26110601\|gb\|AA... gi\|117625819, gi... - gi\|117625819\|ref\|YP_859142.1\| hypothetical protein APECO1_2913 [Escherichia coli APEC O1], gi\|115514... gi\|227839279, gi... - gi\|227883699\|ref\|ZP_04001504.1\| endoglucanase [Escherichia coli 83972], gi\|227839279\|gb\|EEJ49745.1\| ... gi\|91213044, gi\|... - gi\|91213044\|ref\|YP_543030.1\| hypothetical protein UTI89_C4070 [Escherichia coli UTI89], gi\|91074618\|... gi\|218429386, gi... - gi\|218691822\|ref\|YP_002400034.1\| putative endoglucanase involved in cellulose biosynthesis [Escheric...	0.0	[1..559]	[1..559]

Back

Predicted Domain #1

Region A:
Residues: [1-120]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTQHTQTPSM PSPLWQYWRG LSGWNFYFLV KFGLLWAGYL NFHPLLNLVF MAFLLMPIPK  60
   61 YRLHRLRHWI AIPVGFALFW HDTWLPGPQS IMSQGTQVAE FSSGYLLDLI ARFINWQMIG 120
  121

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [121-198]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AIFVLLVAWL FLSQWIRVTV FVVAIMVWLN VLTLTGPVFT LWPAGQPTDT VTTTGGNAAA  60
   61 TVATAGDKPV IGDMPAQT

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [199-559]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APPTTANLNA WLNTFYAAEE KRKTTFPAQL PPDAQPFDLL VINICSLSWS DVEAAGLMSH  60
   61 PLWSHFDILF KHFNSGTSYS GPAAIRLLRA SCGQPSHTRL YQPANNECYL FDNLAKLGFT 120
  121 QHLMMDHNGE FGGFLKEVRE NGGMQSELMN QSGLPTALLS FDGSPVYDDL AVLNRWLTGE 180
  181 EREANSRSAT FFNLLPLHDG NHFPGVSKTA DYKIRAQKLF DELDAFFTEL EKSGRKVMVV 240
  241 VVPEHGGALK GDRMQISGLR DIPSPSITNV PAGVKFFGMK APHEGAPIDI NQPSSYLAIS 300
  301 ELVVRAVDGK LFTEDSVNWN KLTSNLPQTA PVSENANAVV IQYQGKPYVR LNGGDWVPYP 360
  361 Q

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	0.963
Match:	1n2lA
Description:	Crystal structure of a covalent intermediate of endogenous human arylsulfatase A
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.59360536063495	bayes_pls_golite062009
hydrolase activity	1.03691241092574	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.731651910372124	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: