YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|16504718, gi\|...
Organism:	Salmonella enterica subsp. enterica serovar Typhi
Length:	678 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|16504718, gi|....

Description	E-value	Query Range	Subject Range
gi\|62130113, gi\|... - gi\|62182480\|ref\|YP_218897.1\| alpha-glucosidase [Salmonella enterica subsp. enterica serovar Cholerae... gi\|224585829, gi... - gi\|224585829\|ref\|YP_002639628.1\| putative glycosyl hydrolase [Salmonella enterica subsp. enterica se...	0.0	[1..678]	[1..678]
gi\|6752894 - gi\|6752894\|gb\|AAF27925.1\|AF220438_5 putative glycosidase [Salmonella typhimurium] gi\|6752894\|gb\|AA... - putative glycosidase [Salmonella typhimurium]	0.0	[1..678]	[1..678]
gi\|205329991, gi... - gi\|205329991\|gb\|EDZ16755.1\| alpha-glucosidase YihQ [Salmonella enterica subsp. enterica serovar 4,[5... gi\|16767284, gi\|... - gi\|16767284\|ref\|NP_462899.1\| alpha-glucosidase [Salmonella typhimurium LT2], gi\|16422581\|gb\|AAL22858... lcl\|NC_016856.1_... - [gene=yihQ] [protein=alpha-glucosidase] [protein_id=YP_005240285.1] [location=complement(4242249..42...	0.0	[1..678]	[1..678]
gi\|56130122, gi\|... - gi\|56415865\|ref\|YP_152940.1\| alpha-glucosidase [Salmonella enterica subsp. enterica serovar Paratyph... gi\|197364794, gi... - gi\|197364794\|ref\|YP_002144431.1\| alpha-glucosidase [Salmonella enterica subsp. enterica serovar Para...	0.0	[1..678]	[1..678]
LYAG_MOUSE - Lysosomal alpha-glucosidase OS=Mus musculus GN=Gaa PE=1 SV=2	0.0	[52..677]	[178..834]
LYAG_BOVIN - Lysosomal alpha-glucosidase OS=Bos taurus GN=GAA PE=2 SV=1	0.0	[52..677]	[165..818]
gi\|170083350, gi... - gi\|170083350\|ref\|YP_001732670.1\| alpha-glucosidase [Escherichia coli str. K-12 substr. DH10B], gi\|16... gi\|89110150, gi\|... - gi\|89110150\|ref\|AP_003930.1\| alpha-glucosidase [Escherichia coli str. K-12 substr. W3110], gi\|856761... gi\|188496466, gi... - gi\|188496466\|ref\|ZP_03003736.1\| glycosyl hydrolase, family 31 [Escherichia coli 53638], gi\|188491665... gi\|238859969, gi... - gi\|238902945\|ref\|YP_002928741.1\| alpha-glucosidase [Escherichia coli BW2952], gi\|238859969\|gb\|ACR619... EG11843 - putative sulpholipid alpha-glucosidase; alpha-glucosyl fluoride glucosidase / Putative sulpholipid a... EG11843 - putative sulpholipid alpha-glucosidase; alpha-glucosyl fluoride glucosidase / Putative sulpholipid a... YIHQ_ECOLI - Putative family 31 glucosidase yihQ - Escherichia coli	0.0	[1..678]	[1..678]
gi\|109118860, gi... - gi\|109118860\|ref\|XP_001110024.1\| PREDICTED: acid alpha-glucosidase isoform 3 [Macaca mulatta], gi\|10...	0.0	[51..677]	[177..833]
gi\|217326539, gi... - gi\|217326539\|ref\|ZP_03442623.1\| glycosyl hydrolase, family 31 [Escherichia coli O157:H7 str. TW14588... gi\|254595271, gi... - gi\|254795871\|ref\|YP_003080708.1\| alpha-glucosidase [Escherichia coli O157:H7 str. TW14359], gi\|25459... gi\|25500377, gi\|... - pir\|\|G86075 probable glycosidase yihQ [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|195937516 - gi\|195937516\|ref\|ZP_03082898.1\| alpha-glucosidase [Escherichia coli O157:H7 str. EC4024] gi\|189378072, gi... - gi\|189378072\|gb\|EDU96488.1\| glycosyl hydrolase, family 31 [Escherichia coli O157:H7 str. EC508], gi\|... gi\|12518760, gi\|... - gi\|15804463\|ref\|NP_290503.1\| alpha-glucosidase [Escherichia coli O157:H7 EDL933], gi\|12518760\|gb\|AAG... gi\|189001531, gi... - gi\|189001531\|gb\|EDU70517.1\| glycosyl hydrolase, family 31 [Escherichia coli O157:H7 str. EC4076], gi... gi\|13364276, gi\|... - gi\|15834054\|ref\|NP_312827.1\| putative glycosidase [Escherichia coli O157:H7], gi\|13364276\|dbj\|BAB382... gi\|168775301, gi... - gi\|187769160\|gb\|EDU33004.1\| glycosyl hydrolase, family 31 [Escherichia coli O157:H7 str. EC4196], gi... gi\|13364276, gi\|... - gi\|15834054\|ref\|NP_312827.1\| alpha-glucosidase [Escherichia coli O157:H7 str. Sakai], gi\|13364276\|db... gi\|209159941, gi... - gi\|209398541\|ref\|YP_002273394.1\| glycosyl hydrolase, family 31 [Escherichia coli O157:H7 str. EC4115... gi\|208821291, gi... - gi\|208821291\|ref\|ZP_03261611.1\| glycosyl hydrolase, family 31 [Escherichia coli O157:H7 str. EC4042]... gi\|208734788, gi... - gi\|208813511\|ref\|ZP_03254840.1\| glycosyl hydrolase, family 31 [Escherichia coli O157:H7 str. EC4045]... gi\|208725792, gi... - gi\|208805991\|ref\|ZP_03248328.1\| glycosyl hydrolase, family 31 [Escherichia coli O157:H7 str. EC4206]... gi\|189362584, gi... - gi\|189362584\|gb\|EDU81003.1\| glycosyl hydrolase, family 31 [Escherichia coli O157:H7 str. EC4486], gi... gi\|189367927, gi... - gi\|189367927\|gb\|EDU86343.1\| glycosyl hydrolase, family 31 [Escherichia coli O157:H7 str. EC4501], gi... gi\|189357105, gi... - gi\|189357105\|gb\|EDU75524.1\| glycosyl hydrolase, family 31 [Escherichia coli O157:H7 str. EC4401], gi... gi\|188016797, gi... - gi\|188016797\|gb\|EDU54919.1\| glycosyl hydrolase, family 31 [Escherichia coli O157:H7 str. EC4113], gi...	0.0	[1..678]	[1..678]

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Predicted Domain #1

Region A:
Residues: [1-109]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSLPQRSTD FELTTSQDGF ALSWQQRLIL RHSAENPCLW IGAGVADIDM FRGNFSIKDK  60
   61 LNEKIALTEA TVSELPDGWL VQFSRGATIS ATLRISADEA GRLTLDLQN

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.275	c.95.1	Thiolase-like
View	Download	0.403	d.81.1	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain

Predicted Domain #2

Region A:
Residues: [110-678]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDLHHNRIWL RLAANPDDHI YGCGEQFSYF DLRGKPFPLW TSEQGVGRNK TSYVTWQADC  60
   61 KENAGGDYYW TFFPQPTFVS TQKYYCHVDN SCYMNFDFSA PEYHELALWE DKTTLRFECA 120
  121 DTYIALLEKL TALLGRQPEL PDWVYDGVTL GIQGGTEVCQ QKLDTMRNAG VKVNGIWAQD 180
  181 WSGIRMTSFG KRVMWNWKWN SDNYPQLDSR IKQWKEEGVQ FLSYINPYVA SDKDLCAEAA 240
  241 RHGYLAKDAT GGDYLVEFGE FYGGVVDLTN PEAYDWFKDV IKKNMIALGC SGWMADFGEY 300
  301 LPTDTYLHNG VSAEIMHNAW PALWAKCNYE ALQETGKLGE ILFFMRAGYT GSQKYSTMMW 360
  361 AGDQNVDWSL DDGLASVVPA ALSLAMTGHG LHHSDIGGYT TLFDMKRSKE LLLRWCDFSA 420
  421 FTPMMRTHEG NRPGNNWQFD GDAETIAHFA RMTTVFTTLK PYLKQAVAQN AATGLPVMRP 480
  481 LFLHYENDAA TYTLKYQYLL GQDLLVAPVH EQGRCDWTLY LPEDHWVNIW TGEAHHGGEI 540
  541 TVDAPIGKPP VFYRAKSEWA LLFASLRNI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	122.0
Match:	1we5A
Description:	Crystal Structure of Alpha-Xylosidase from Escherichia coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrolase activity, acting on glycosyl bonds	3.1190602686215	bayes_pls_golite062009
hydrolase activity, hydrolyzing O-glycosyl compounds	2.98773241907716	bayes_pls_golite062009
catalytic activity	2.22613067995402	bayes_pls_golite062009
hydrolase activity	1.107656067558	bayes_pls_golite062009
trehalase activity	0.8585169360333	bayes_pls_golite062009
glucosidase activity	0.58717079348538	bayes_pls_golite062009
alpha,alpha-phosphotrehalase activity	0.478490799601761	bayes_pls_golite062009
hexosaminidase activity	0.16438321606077	bayes_pls_golite062009
amylase activity	0.0914002140078796	bayes_pls_golite062009
alpha-amylase activity	0.0521244165288097	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: