YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|16761885
Organism:	Salmonella enterica subsp. enterica serovar Typhi str. CT18
Length:	239 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|16761885.

Description	E-value	Query Range	Subject Range
gi\|112702911 - gi\|112702911\|emb\|CAL34130.1\| hypothetical protein [Enterobacter sakazakii]	3.0E-46	[1..239]	[33..271]
gi\|77961509, gi\|... - gi\|77961509\|ref\|ZP_00825345.1\| COG0220: Predicted S-adenosylmethionine-dependent methyltransferase [...	9.0E-46	[1..239]	[1..239]
gi\|186699683, gi... - gi\|186896657\|ref\|YP_001873769.1\| tRNA (guanine-N(7)-)-methyltransferase [Yersinia pseudotuberculosis... TRMB_YERP3 - tRNA (guanine-N(7)-)-methyltransferase OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 31758...	1.0E-45	[1..239]	[1..239]
gi\|170023070, gi... - gi\|170023070\|ref\|YP_001719575.1\| tRNA (guanine-N(7)-)-methyltransferase [Yersinia pseudotuberculosis... TRMB_YERPS - tRNA (guanine-N(7)-)-methyltransferase OS=Yersinia pseudotuberculosis GN=trmB PE=3 SV=1 TRMB_YERPS - tRNA (guanine-N(7)-)-methyltransferase OS=Yersinia pseudotuberculosis serotype I (strain IP32953) GN...	1.0E-45	[1..239]	[1..239]
gi\|162354476, gi... - gi\|77633208\|ref\|ZP_00795352.1\| COG0220: Predicted S-adenosylmethionine-dependent methyltransferase [... gi\|165923261, gi... - gi\|165925061\|ref\|ZP_02220893.1\| tRNA (guanine-N(7)-)-methyltransferase [Yersinia pestis biovar Orien... gi\|165914683, gi... - gi\|165937209\|ref\|ZP_02225773.1\| tRNA (guanine-N(7)-)-methyltransferase [Yersinia pestis biovar Orien... gi\|166010280, gi... - gi\|166010280\|ref\|ZP_02231178.1\| tRNA (guanine-N(7)-)-methyltransferase [Yersinia pestis biovar Antiq... gi\|166212782, gi... - gi\|166212782\|ref\|ZP_02238817.1\| tRNA (guanine-N(7)-)-methyltransferase [Yersinia pestis biovar Antiq... gi\|167050525, gi... - gi\|167399817\|ref\|ZP_02305335.1\| tRNA (guanine-N(7)-)-methyltransferase [Yersinia pestis biovar Antiq... gi\|45443229, gi\|... - gi\|45443229\|ref\|NP_994768.1\| tRNA (guanine-N(7))-methyltransferase [Yersinia pestis biovar Microtus ... gi\|167421899, gi... - gi\|167421899\|ref\|ZP_02313652.1\| tRNA (guanine-N(7)-)-methyltransferase [Yersinia pestis biovar Orien... gi\|22127214, gi\|... - gi\|22127214\|ref\|NP_670637.1\| tRNA (guanine-N(7))-methyltransferase [Yersinia pestis KIM], gi\|2196028... gi\|167426711, gi... - gi\|167426711\|ref\|ZP_02318464.1\| tRNA (guanine-N(7)-)-methyltransferase [Yersinia pestis biovar Media... TRMB_YERPA - tRNA (guanine-N(7)-)-methyltransferase OS=Yersinia pestis bv. Antiqua (strain Antiqua) GN=trmB PE=3 ... gi\|15979020, gi\|... - gi\|218928122\|ref\|YP_002345997.1\| tRNA (guanine-N(7)-)-methyltransferase [Yersinia pestis CO92], gi\|1... gi\|229842568, gi... - gi\|229842568\|ref\|ZP_04462723.1\| tRNA (m7G46) methyltransferase, SAM-dependent [Yersinia pestis biova... TRMB_YERPN - tRNA (guanine-N(7)-)-methyltransferase OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=trmB PE=3... gi\|229840871, gi... - gi\|229840871\|ref\|ZP_04461030.1\| tRNA (m7G46) methyltransferase, SAM-dependent [Yersinia pestis biova... gi\|229837647, gi... - gi\|229837647\|ref\|ZP_04457809.1\| tRNA (m7G46) methyltransferase, SAM-dependent [Yersinia pestis Pesto... TRMB_YERPE - tRNA (guanine-N(7)-)-methyltransferase OS=Yersinia pestis GN=trmB PE=3 SV=1 TRMB_YERPP - tRNA (guanine-N(7)-)-methyltransferase OS=Yersinia pestis (strain Pestoides F) GN=trmB PE=3 SV=1 gi\|149290655, gi... - gi\|149367041\|ref\|ZP_01889074.1\| Putative methyltransferase [Yersinia pestis CA88-4125], gi\|149290655...	1.0E-45	[1..239]	[1..239]
gi\|77974451 - gi\|77974451\|ref\|ZP_00829991.1\| COG0220: Predicted S-adenosylmethionine-dependent methyltransferase [...	1.0E-45	[1..239]	[14..252]
gi\|77956386 - gi\|77956386\|ref\|ZP_00820489.1\| COG0220: Predicted S-adenosylmethionine-dependent methyltransferase [...	4.0E-45	[1..239]	[1..239]
gi\|77976486 - gi\|77976486\|ref\|ZP_00831972.1\| COG0220: Predicted S-adenosylmethionine-dependent methyltransferase [...	5.0E-45	[1..239]	[14..252]
lcl\|NC_016856.1_... - [gene=trmB] [protein=tRNA (guanine-N(7))-methyltransferase] [protein_id=YP_005239256.1] [location=co... TRMB_SALTY - tRNA (guanine-N(7)-)-methyltransferase OS=Salmonella typhimurium GN=trmB PE=3 SV=1 TRMB_SALTY - tRNA (guanine-N(7)-)-methyltransferase OS=Salmonella typhimurium GN=trmB PE=3 SV=1 TRMB_SALTY - tRNA (guanine-N(7)-)-methyltransferase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 70072...	2.0E-44	[1..239]	[1..239]
TRMB_PHOLL - tRNA (guanine-N(7)-)-methyltransferase OS=Photorhabdus luminescens subsp. laumondii GN=trmB PE=3 SV=... TRMB_PHOLL - tRNA (guanine-N(7)-)-methyltransferase OS=Photorhabdus luminescens subsp. laumondii (strain DSM 1513...	4.0E-44	[1..239]	[1..239]

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Predicted Domain #1

Region A:
Residues: [1-239]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKNDVISPEF DENGRPLRRI RSFVRRQGRL TKGQEHALEN YWPVMGVEFS EAPVDFATLF  60
   61 GREAPVTLEI GFGMGASLVA MAKARPEQNF LGIEVHSPGV GACLASAHEE GVENLHVMCH 120
  121 DAVEVLHKMI PDNSLSMVQL FFPDPWHKAR HNKRRIVQVP FAELVLSKLK LGGVFHMATD 180
  181 WEAYAEHMLE VMSSIDGYKN LSESNDYVPR PESRPVTKFE QRGHRLGHGV WDLMFERVK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	33.045757
Match:	1yzhA
Description:	Crystal Structure of the Conserved Hypothetical Protein, Methyltransferase from Streptococcus pneumoniae TIGR4
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
methyltransferase activity	3.57681394097837	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	3.49392219433935	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	3.39429041855776	bayes_pls_golite062009
RNA methyltransferase activity	3.07428840534971	bayes_pls_golite062009
rRNA methyltransferase activity	2.29640050660273	bayes_pls_golite062009
transferase activity	2.22303238506686	bayes_pls_golite062009
tRNA methyltransferase activity	1.95598912777096	bayes_pls_golite062009
catalytic activity	1.25333584501255	bayes_pls_golite062009
N-methyltransferase activity	0.548554528454085	bayes_pls_golite062009
rRNA (adenine) methyltransferase activity	0.533090627724779	bayes_pls_golite062009
rRNA (adenine-N6,N6-)-dimethyltransferase activity	0.455449410561251	bayes_pls_golite062009
tRNA (guanine) methyltransferase activity	0.203168546434167	bayes_pls_golite062009
protein methyltransferase activity	0.0313727777808413	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: