YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|16421115, gi\|...
Organism:	Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Length:	183 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|16421115, gi|....

Description	E-value	Query Range	Subject Range
gi\|197361490, gi... - gi\|197361490\|ref\|YP_002141126.1\| tRNA-specific adenosine deaminase [Salmonella enterica subsp. enter... gi\|56126812, gi\|... - gi\|56412555\|ref\|YP_149630.1\| tRNA-specific adenosine deaminase [Salmonella enterica subsp. enterica ...	1.0E-57	[1..183]	[1..183]
TADA_SHIFL - tRNA-specific adenosine deaminase (EC 3.5.4.-) - Shigella flexneri gi\|218352918, gi... - gi\|218696186\|ref\|YP_002403853.1\| tRNA-specific adenosine deaminase [Escherichia coli 55989], gi\|2183... gi\|24113886, gi\|... - gi\|24113886\|ref\|NP_708396.1\| tRNA-specific adenosine deaminase [Shigella flexneri 2a str. 301], gi\|2... gi\|218361852, gi... - gi\|218555084\|ref\|YP_002387997.1\| tRNA-specific adenosine deaminase [Escherichia coli IAI1], gi\|21836... gi\|254289295, gi... - gi\|254289295\|ref\|YP_003055043.1\| tRNA-specific adenosine deaminase [Escherichia coli BL21(DE3)], gi\|... gi\|218547914, gi... - gi\|218547914\|ref\|YP_002381705.1\| tRNA-specific adenosine deaminase [Escherichia fergusonii ATCC 3546... YFHC_ECOLI, TADA... - (P30134) Hypothetical protein yfhC, tRNA-specific adenosine deaminase (EC 3.5.4.-) - Escherichia col... gi\|209920038, gi... - gi\|209920038\|ref\|YP_002294122.1\| tRNA-specific adenosine deaminase [Escherichia coli SE11], gi\|20991... gi\|30042202, gi\|... - gi\|30063946\|ref\|NP_838117.1\| tRNA-specific adenosine deaminase [Shigella flexneri 2a str. 2457T], gi... gi\|82545011, gi\|... - gi\|82545011\|ref\|YP_408958.1\| tRNA-specific adenosine deaminase [Shigella boydii Sb227], gi\|81246422\|... gi\|1788911, gi\|1... - gi\|1788911\|gb\|AAC75612.1\| tRNA-specific adenosine deaminase [Escherichia coli K12], gi\|16130484\|ref\|... gi\|85675450, gi\|... - gi\|89109365\|ref\|AP_003145.1\| tRNA-specific adenosine deaminase [Escherichia coli str. K-12 substr. W... gi\|157067716, gi... - gi\|157162036\|ref\|YP_001459354.1\| tRNA-specific adenosine deaminase [Escherichia coli HS], gi\|1570677... gi\|1033148\|gb\|AA... - alternate name yfhC; orf178 of GenBank Accession Number X72336 gi\|188491218, gi... - gi\|188496019\|ref\|ZP_03003289.1\| tRNA-specific adenosine deaminase [Escherichia coli 53638], gi\|18849... gi\|187427445, gi... - gi\|187730453\|ref\|YP_001881338.1\| tRNA-specific adenosine deaminase [Shigella boydii CDC 3083-94], gi... gi\|253974435, gi... - gi\|254162534\|ref\|YP_003045642.1\| tRNA-specific adenosine deaminase [Escherichia coli B str. REL606],... gi\|251785887, gi... - gi\|251785887\|ref\|YP_003000191.1\| hypothetical protein B21_02417 [Escherichia coli BL21], gi\|24237816...	6.0E-54	[1..175]	[1..175]
gi\|115513905, gi... - gi\|117624781\|ref\|YP_853694.1\| tRNA-specific adenosine deaminase [Escherichia coli APEC O1], gi\|11551... gi\|218690674, gi... - gi\|218690674\|ref\|YP_002398886.1\| tRNA-specific adenosine deaminase [Escherichia coli ED1a], gi\|21842... gi\|218366248, gi... - gi\|218559479\|ref\|YP_002392392.1\| tRNA-specific adenosine deaminase [Escherichia coli S88], gi\|218366... TADA_ECO57 - tRNA-specific adenosine deaminase (EC 3.5.4.-) - Escherichia coli O157:H7 gi\|25303867, gi\|... - pir\|\|E85901 probable deaminase yfhC [imported] - Escherichia coli (strain O157:H7, substrain EDL933... gi\|189009982, gi... - gi\|189009982\|ref\|ZP_02803540.2\| tRNA-specific adenosine deaminase [Escherichia coli O157:H7 str. EC4... gi\|12516972, gi\|... - gi\|15803084\|ref\|NP_289115.1\| tRNA-specific adenosine deaminase [Escherichia coli O157:H7 EDL933], gi... gi\|91073458, gi\|... - gi\|91211884\|ref\|YP_541870.1\| tRNA-specific adenosine deaminase [Escherichia coli UTI89], gi\|91073458... gi\|187770595, gi... - gi\|187775816\|ref\|ZP_02798525.2\| tRNA-specific adenosine deaminase [Escherichia coli O157:H7 str. EC4... gi\|13362896, gi\|... - gi\|15832679\|ref\|NP_311452.1\| tRNA-specific adenosine deaminase [Escherichia coli O157:H7 str. Sakai]... gi\|82777934, gi\|... - gi\|82777934\|ref\|YP_404283.1\| tRNA-specific adenosine deaminase [Shigella dysenteriae Sd197], gi\|8124... gi\|110642721, gi... - gi\|110642721\|ref\|YP_670451.1\| tRNA-specific adenosine deaminase [Escherichia coli 536], gi\|110344313... gi\|194432153, gi... - gi\|194432153\|ref\|ZP_03064442.1\| tRNA-specific adenosine deaminase [Shigella dysenteriae 1012], gi\|19... gi\|237705067, gi... - gi\|237705067\|ref\|ZP_04535548.1\| tRNA-specific adenosine deaminase [Escherichia sp. 3_2_53FAA], gi\|22... gi\|190907120, gi... - gi\|191172647\|ref\|ZP_03034186.1\| tRNA-specific adenosine deaminase [Escherichia coli F11], gi\|1909071... gi\|189378592, gi... - gi\|189405736\|ref\|ZP_02823945.2\| tRNA-specific adenosine deaminase [Escherichia coli O157:H7 str. EC5... gi\|189405037, gi... - gi\|189405037\|ref\|ZP_02812923.2\| tRNA-specific adenosine deaminase [Escherichia coli O157:H7 str. EC8...	2.0E-53	[1..175]	[1..175]
gi\|74313082, gi\|... - gi\|74313082\|ref\|YP_311501.1\| tRNA-specific adenosine deaminase [Shigella sonnei Ss046], gi\|73856559\|...	2.0E-53	[1..174]	[1..174]
TADA_ECOL6 - tRNA-specific adenosine deaminase (EC 3.5.4.-) - Escherichia coli O6 gi\|26109329, gi\|... - gi\|26248923\|ref\|NP_754963.1\| tRNA-specific adenosine deaminase [Escherichia coli CFT073], gi\|2610932... gi\|227887593, gi... - gi\|227887593\|ref\|ZP_04005398.1\| tRNA-specific adenosine deaminase [Escherichia coli 83972], gi\|22783...	6.0E-53	[1..175]	[1..175]
gi\|116184449 - gi\|116184449\|ref\|ZP_01474386.1\| hypothetical protein VEx2w_02003038 [Vibrio sp. Ex25]	2.0E-52	[6..174]	[18..186]
gi\|77809323, gi\|... - gi\|77815675\|ref\|ZP_00814899.1\| Cytidine/deoxycytidylate deaminase, zinc-binding region [Shewanella p...	3.0E-52	[13..177]	[3..167]
gi\|77974711 - gi\|77974711\|ref\|ZP_00830250.1\| COG0590: Cytosine/adenosine deaminases [Yersinia frederiksenii ATCC 3...	5.0E-52	[13..175]	[28..190]
gi\|110616037, gi... - gi\|110806489\|ref\|YP_690009.1\| tRNA-specific adenosine deaminase [Shigella flexneri 5 str. 8401], gi\|...	7.0E-52	[12..175]	[1..164]
gi\|126175184, gi... - gi\|68543670\|ref\|ZP_00583366.1\| Cytidine/deoxycytidylate deaminase, zinc-binding region [Shewanella b...	7.0E-52	[14..177]	[8..171]

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Predicted Domain #1

Region A:
Residues: [1-183]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPPAFITGVT SLSDVELDHE YWMRHALTLA KRAWDEREVP VGAVLVHNHR VIGEGWNRPI  60
   61 GRHDPTAHAE IMALRQGGLV LQNYRLLDTT LYVTLEPCVM CAGAMVHSRI GRVVFGARDA 120
  121 KTGAAGSLID VLHHPGMNHR VEIIEGVLRD ECATLLSDFF RMRRQEIKAL KKADRAEGAG 180
  181 PAV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	53.221849
Match:	1z3aA
Description:	Crystal structure of tRNA adenosine deaminase TadA from Escherichia coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
cytidine deaminase activity	4.42667374679603	bayes_pls_golite062009
deaminase activity	2.76997916054448	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	2.27736397496642	bayes_pls_golite062009
catalytic activity	1.70756445127105	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	1.51294035758003	bayes_pls_golite062009
methyltransferase activity	1.24697538679504	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	1.16679252289538	bayes_pls_golite062009
IMP cyclohydrolase activity	1.11605611485835	bayes_pls_golite062009
binding	1.05190374148481	bayes_pls_golite062009
phosphoribosylaminoimidazolecarboxamide formyltransferase activity	0.827438033765078	bayes_pls_golite062009
transferase activity	0.771056210634777	bayes_pls_golite062009
hydrolase activity	0.452099352697972	bayes_pls_golite062009
cyclohydrolase activity	0.308525511259279	bayes_pls_golite062009
hydroxymethyl-, formyl- and related transferase activity	0.1546696349714	bayes_pls_golite062009
protein binding	0.095488575269861	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: