YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|16761203
Organism:	Salmonella enterica subsp. enterica serovar Typhi str. CT18
Length:	761 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|16761203.

Description	E-value	Query Range	Subject Range
gi\|56412826, gi\|... - gi\|56412826\|ref\|YP_149901.1\| ribonucleotide-diphosphate reductase subunit alpha [Salmonella enterica... gi\|62128483, gi\|... - gi\|62180850\|ref\|YP_217267.1\| ribonucleotide-diphosphate reductase subunit alpha [Salmonella enterica... gi\|197361759, gi... - gi\|197361759\|ref\|YP_002141395.1\| ribonucleotide-diphosphate reductase subunit alpha [Salmonella ente... gi\|205344941, gi... - gi\|205344941\|gb\|EDZ31705.1\| ribonucleoside-diphosphate reductase, alpha subunit [Salmonella enterica... gi\|168466026, gi... - gi\|195631245\|gb\|EDX49805.1\| ribonucleoside-diphosphate reductase, alpha subunit [Salmonella enterica... gi\|205349577, gi... - gi\|205349577\|gb\|EDZ36208.1\| ribonucleoside-diphosphate reductase, alpha subunit [Salmonella enterica...	0.0	[1..761]	[1..761]
lcl\|NC_016856.1_... - [gene=nrdA] [protein=ribonucleotide-diphosphate reductase subunit alpha] [protein_id=YP_005238348.1]... gi\|205329161, gi... - gi\|205329161\|gb\|EDZ15925.1\| ribonucleoside-diphosphate reductase, alpha subunit [Salmonella enterica... RIR1_SALTY - Ribonucleoside-diphosphate reductase 1 subunit alpha OS=Salmonella typhimurium GN=nrdA PE=3 SV=1 RIR1_SALTY - Ribonucleoside-diphosphate reductase 1 subunit alpha OS=Salmonella typhimurium GN=nrdA PE=3 SV=1 RIR1_SALTY - Ribonucleoside-diphosphate reductase 1 subunit alpha OS=Salmonella typhimurium (strain LT2 / SGSC141...	0.0	[1..761]	[1..761]
gi\|218361565, gi... - gi\|218554797\|ref\|YP_002387710.1\| ribonucleotide-diphosphate reductase subunit alpha [Escherichia col... gi\|75259700, gi\|... - gi\|75259700\|ref\|ZP_00731002.1\| COG0209: Ribonucleotide reductase, alpha subunit [Escherichia coli E2... gi\|193068151, gi... - gi\|75238025\|ref\|ZP_00722030.1\| COG0209: Ribonucleotide reductase, alpha subunit [Escherichia coli E1... gi\|75230376, gi\|... - gi\|75230376\|ref\|ZP_00716866.1\| COG0209: Ribonucleotide reductase, alpha subunit [Escherichia coli B7... gi\|194427206, gi... - gi\|75211645\|ref\|ZP_00711724.1\| COG0209: Ribonucleotide reductase, alpha subunit [Escherichia coli B1... gi\|209919686, gi... - gi\|209919686\|ref\|YP_002293770.1\| ribonucleotide-diphosphate reductase subunit alpha [Escherichia col...	0.0	[1..761]	[1..761]
gi\|24113614, gi\|... - gi\|24113614\|ref\|NP_708124.1\| ribonucleotide-diphosphate reductase subunit alpha [Shigella flexneri 2... gi\|30041923, gi\|... - gi\|30063668\|ref\|NP_837839.1\| ribonucleotide-diphosphate reductase subunit alpha [Shigella flexneri 2...	0.0	[1..761]	[1..761]
gi\|188492275, gi... - gi\|75512710\|ref\|ZP_00735212.1\| COG0209: Ribonucleotide reductase, alpha subunit [Escherichia coli 53...	0.0	[1..761]	[1..761]
gi\|15802781, gi\|... - gi\|15802781\|ref\|NP_288808.1\| ribonucleotide-diphosphate reductase subunit alpha [Escherichia coli O1... gi\|218690397, gi... - gi\|218690397\|ref\|YP_002398609.1\| ribonucleotide-diphosphate reductase subunit alpha [Escherichia col... gi\|15832371, gi\|... - gi\|15832371\|ref\|NP_311144.1\| ribonucleotide-diphosphate reductase alpha subunit [Escherichia coli O1... gi\|218352572, gi... - gi\|218695840\|ref\|YP_002403507.1\| ribonucleotide-diphosphate reductase subunit alpha [Escherichia col... gi\|218370691, gi... - gi\|218700705\|ref\|YP_002408334.1\| ribonucleotide-diphosphate reductase subunit alpha [Escherichia col... gi\|218705764, gi... - gi\|218705764\|ref\|YP_002413283.1\| ribonucleotide-diphosphate reductase subunit alpha [Escherichia col... gi\|226901076, gi... - gi\|237704710\|ref\|ZP_04535191.1\| ribonucleotide-diphosphate reductase subunit alpha [Escherichia sp. ... gi\|227887292, gi... - gi\|227887292\|ref\|ZP_04005097.1\| ribonucleotide-diphosphate reductase subunit alpha [Escherichia coli... gi\|168761334, gi... - gi\|189368234\|gb\|EDU86650.1\| ribonucleoside-diphosphate reductase, alpha subunit [Escherichia coli O1... gi\|168787140, gi... - gi\|189372942\|gb\|EDU91358.1\| ribonucleoside-diphosphate reductase, alpha subunit [Escherichia coli O1... gi\|170519980, gi... - gi\|170682262\|ref\|YP_001744430.1\| ribonucleoside-diphosphate reductase, alpha subunit [Escherichia co... gi\|217320335, gi... - gi\|217327968\|ref\|ZP_03444051.1\| ribonucleoside-diphosphate reductase, alpha subunit [Escherichia col... gi\|218365920, gi... - gi\|218559151\|ref\|YP_002392064.1\| ribonucleotide-diphosphate reductase subunit alpha [Escherichia col... gi\|157078736, gi... - gi\|75187023\|ref\|ZP_00700290.1\| COG0209: Ribonucleotide reductase, alpha subunit [Escherichia coli E2... gi\|115513552, gi... - gi\|117624428\|ref\|YP_853341.1\| ribonucleotide-diphosphate reductase subunit alpha [Escherichia coli A... gi\|91211527, gi\|... - gi\|91211527\|ref\|YP_541513.1\| ribonucleotide-diphosphate reductase subunit alpha [Escherichia coli UT... gi\|26248622, gi\|... - gi\|26248622\|ref\|NP_754662.1\| ribonucleotide-diphosphate reductase subunit alpha [Escherichia coli CF... gi\|15832371, gi\|... - gi\|15832371\|ref\|NP_311144.1\| ribonucleotide-diphosphate reductase subunit alpha [Escherichia coli O1... gi\|209765530, gi... - pir\|\|G85862 hypothetical protein nrdA [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|190909741, gi... - gi\|75243049\|ref\|ZP_00726755.1\| COG0209: Ribonucleotide reductase, alpha subunit [Escherichia coli F1... gi\|110642442, gi... - gi\|110642442\|ref\|YP_670172.1\| ribonucleotide-diphosphate reductase subunit alpha [Escherichia coli 5...	0.0	[1..761]	[1..761]
gi\|187731504, gi... - gi\|75177970\|ref\|ZP_00698032.1\| COG0209: Ribonucleotide reductase, alpha subunit [Shigella boydii BS5...	0.0	[1..761]	[1..761]
gi\|110615752, gi... - gi\|110806204\|ref\|YP_689724.1\| ribonucleotide-diphosphate reductase subunit alpha [Shigella flexneri ...	0.0	[1..761]	[1..761]
gi\|238901408, gi... - gi\|238901408\|ref\|YP_002927204.1\| ribonucleoside diphosphate reductase 1, alpha subunit [Escherichia ... gi\|242377868, gi... - gi\|251785595\|ref\|YP_002999899.1\| hypothetical protein B21_02119 [Escherichia coli BL21], gi\|24237786... gi\|254289006, gi... - gi\|254289006\|ref\|YP_003054754.1\| ribonucleotide-diphosphate reductase alpha subunit [Escherichia col... gi\|253974146, gi... - gi\|254162245\|ref\|YP_003045353.1\| ribonucleotide-diphosphate reductase alpha subunit [Escherichia col... gi\|89109051, gi\|... - gi\|89109051\|ref\|AP_002831.1\| ribonucleoside diphosphate reductase 1, alpha subunit [Escherichia coli... EG10660 - ribonucleoside-diphosphate reductase 1, alpha subunit / Ribonucleoside-diphosphate reductase 1, alph... RIR1_ECOLI - Ribonucleoside-diphosphate reductase 1 subunit alpha (EC 1.17.4.1) (Ribonucleoside-diphosphate reduc... gi\|169889687, gi... - gi\|170081852\|ref\|YP_001731172.1\| ribonucleoside diphosphate reductase 1, alpha subunit [Escherichia ... gi\|75196276, gi\|... - gi\|75196276\|ref\|ZP_00706346.1\| COG0209: Ribonucleotide reductase, alpha subunit [Escherichia coli HS... gi\|73856231, gi\|... - gi\|74312754\|ref\|YP_311173.1\| ribonucleotide-diphosphate reductase subunit alpha [Shigella sonnei Ss0... gi\|169754381, gi... - gi\|170019453\|ref\|YP_001724407.1\| ribonucleotide-diphosphate reductase subunit alpha [Escherichia col... EG10660 - ribonucleoside-diphosphate reductase 1, alpha subunit / Ribonucleoside-diphosphate reductase 1, alph... gi\|194418393, gi... - gi\|194433299\|ref\|ZP_03065579.1\| ribonucleoside-diphosphate reductase, alpha subunit [Shigella dysent... gi\|194436240, gi... - gi\|83588220\|ref\|ZP_00926845.1\| COG0209: Ribonucleotide reductase, alpha subunit [Escherichia coli 10...	0.0	[1..761]	[1..761]
gi\|81241791, gi\|... - gi\|82777643\|ref\|YP_403992.1\| ribonucleotide-diphosphate reductase subunit alpha [Shigella dysenteria...	0.0	[1..761]	[1..761]

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Predicted Domain #1

Region A:
Residues: [1-761]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNQSLLVTKR DGRTERINLD KIHRVLDWAA EGLNNVSVSQ VELRSHIQFY DGIKTSDIHE  60
   61 TIIKAAADLI SRDAPDYQYL AARLAIFHLR KKAFGQFEPP ALYHHVVKMV ELGKYDNHLL 120
  121 EDYTEEEFKQ MDSFIVHDRD MTFSYAAVKQ LEGKYLVQNR VTGEIYESAQ FLYILVVACL 180
  181 FSNYPRETRL DYVKRFYDAV STFKISLPTP IMSGVRTPTR QFSSCVLIEC GDSLDSINAT 240
  241 SSAIVKYVSQ RAGIGINAGR IRALGSPIRG GEAFHTGCIP FYKHFQTAVK SCSQGGVRGG 300
  301 AATLFYPMWH LEVESLLVLK NNRGVEGNRV RHMDYGIQIN KLMYTRLLKG GDITLFSPSD 360
  361 VPGLYDAFFA DQDEFERLYV KYENDDSIRK QRVKAVELFS LMMQERASTG RIYIQNVDHC 420
  421 NTHSPFDPVV APVRQSNLCL EIALPTKPLN DVNDENGEIA LCTLSAFNLG AIKTLDELEE 480
  481 LAILAVRALD ALLDYQDYPI PAAKRGAMGR RTLGIGVINF AYWLAKNGKR YSDGSANNLT 540
  541 HKTFEAIQYY LLKASNELAK EQGACPWFNE TTYAKGILPI DTYKKDLDAI VNEPLHYDWE 600
  601 QLRESIKTHG LRNSTLSALM PSETSSQISN ATNGIEPPRG YVSIKASKDG ILRQVVPDYE 660
  661 HLKDAYELLW EMPNNDGYLQ LVGIMQKFID QSISANTNYD PSRFPSGKVP MQQLLKDLLT 720
  721 AYKFGVKTLY YQNTRDGAED AQDDLAPSIQ DDGCESGACK I

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	2r1rA
Description:	R1 subunit of ribonucleotide reductase, N-terminal domain; R1 subunit of ribonucleotide reductase, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor	14.6351774763867	bayes_pls_golite062009
ribonucleoside-diphosphate reductase activity	14.1611243981741	bayes_pls_golite062009
oxidoreductase activity, acting on CH or CH2 groups	13.9924528137471	bayes_pls_golite062009
class I ribonucleotide reductase activity	8.57315924653024	bayes_pls_golite062009
catalytic activity	1.95058695475279	bayes_pls_golite062009
binding	1.06379703329768	bayes_pls_golite062009
protein binding	0.34900723085369	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: