YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|38234346
Organism:	Corynebacterium diphtheriae NCTC 13129
Length:	228 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|38234346.

Description	E-value	Query Range	Subject Range
gi\|21325123, gi\|... - gi\|62391195\|ref\|YP_226597.1\| nicotinic acid mononucleotide adenylyltransferase [Corynebacterium glut...	238.0	[0..1]	[215..9]
NADD_COREF - Probable nicotinate-nucleotide adenylyltransferase OS=Corynebacterium efficiens (strain DSM 44549 / ... NADD_COREF - Probable nicotinate-nucleotide adenylyltransferase OS=Corynebacterium efficiens GN=nadD PE=3 SV=2	223.0	[0..1]	[203..1]
gi\|25028813, gi\|... - gi\|25028813\|ref\|NP_738867.1\| nicotinic acid mononucleotide adenylyltransferase [Corynebacterium effi...	223.0	[0..1]	[203..16]
gi\|110817837, gi... - gi\|111018307\|ref\|YP_701279.1\| nicotinic acid mononucleotide adenylyltransferase [Rhodococcus jostii ...	217.0	[0..6]	[212..9]
gi\|6714685, gi\|2... - gi\|6714685\|emb\|CAB66257.1\| putative nicotinate-nucleotide adenylyltransferase [Streptomyces coelicol...	216.0	[0..3]	[201..41]
gi\|54014851, gi\|... - gi\|54023343\|ref\|YP_117585.1\| nicotinic acid mononucleotide adenylyltransferase [Nocardia farcinica I...	216.0	[0..5]	[203..15]
gi\|89318320, gi\|... - gi\|89341599\|ref\|ZP_01193842.1\| Cytidyltransferase-related:Probable nicotinate-nucleotide adenylyltra...	214.0	[0..5]	[204..47]
gi\|29609139, gi\|... - gi\|29832021\|ref\|NP_826655.1\| nicotinic acid mononucleotide adenylyltransferase [Streptomyces avermit...	214.0	[0..2]	[201..26]
gi\|71916302, gi\|... - gi\|72162570\|ref\|YP_290227.1\| nicotinic acid mononucleotide adenylyltransferase [Thermobifida fusca Y...	213.0	[0..5]	[203..14]

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Predicted Domain #1

Region A:
Residues: [1-228]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLPRQPSRI GIMGGTFDPI HHGHLVAASE VAARFDLELV VFVPTGQPWQ KVDREVSPAE  60
   61 DRYLMTVIAT ASNPRFTVSR VDIDRPGATY TIDTLRDLRC AYPDSELFFI TGADALGRIL 120
  121 TWRDWEKALE IATFVGVTRP GYVLEEDMLP AQYHDRVELI EIPAMAISST GCRRRAKEGL 180
  181 PVWYLVPDGV VQYIAKRQLY HPSGVDEKRN PAGAAASRLA FDRDNVEQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	50.39794
Match:	1kamA
Description:	Nicotinamide mononucleotide (NMN) adenylyltransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nicotinate-nucleotide adenylyltransferase activity	2.83520682135534	bayes_pls_golite062009
nicotinamide-nucleotide adenylyltransferase activity	2.57110502211876	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	2.54008423253828	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	2.54008423253828	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	2.52910114154477	bayes_pls_golite062009
catalytic activity	2.37674226834122	bayes_pls_golite062009
ligase activity	1.92894388839884	bayes_pls_golite062009
adenylyltransferase activity	1.08055019963499	bayes_pls_golite062009
pantetheine-phosphate adenylyltransferase activity	0.454904507512502	bayes_pls_golite062009
pantoate-beta-alanine ligase activity	0.282286652169846	bayes_pls_golite062009
nucleotidyltransferase activity	0.2293846471193	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: