YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|7449649
Organism:	Escherichia coli
Length:	665 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7449649.

Description	E-value	Query Range	Subject Range
gi\|75188807 - gi\|75188807\|ref\|ZP_00702074.1\| COG2015: Alkyl sulfatase and related hydrolases [Escherichia coli E24...	606.0	[0..1]	[665..1]
gi\|75212011 - gi\|75212011\|ref\|ZP_00712066.1\| COG2015: Alkyl sulfatase and related hydrolases [Escherichia coli B17...	605.0	[0..1]	[665..1]
gi\|75238619 - gi\|75238619\|ref\|ZP_00722608.1\| COG2015: Alkyl sulfatase and related hydrolases [Escherichia coli E11...	604.0	[0..1]	[665..1]
gi\|75259002 - gi\|75259002\|ref\|ZP_00730370.1\| COG2015: Alkyl sulfatase and related hydrolases [Escherichia coli E22...	604.0	[0..1]	[665..1]
gi\|75241133 - gi\|75241133\|ref\|ZP_00725007.1\| COG2015: Alkyl sulfatase and related hydrolases [Escherichia coli F11...	603.0	[0..1]	[665..1]
gi\|227836220, gi... - gi\|227886878\|ref\|ZP_04004683.1\| metallo-beta-lactamase superfamily protein [Escherichia coli 83972],... gi\|26250900, gi\|... - gi\|26250900\|ref\|NP_756940.1\| hypothetical protein c5089 [Escherichia coli CFT073], gi\|26111332\|gb\|AA...	603.0	[0..1]	[665..1]
gi\|91213632, gi\|... - gi\|91213632\|ref\|YP_543618.1\| hypothetical protein UTI89_C4679 [Escherichia coli UTI89], gi\|91075206\|... gi\|115515495, gi... - gi\|117626371\|ref\|YP_859694.1\| hypothetical protein APECO1_2367 [Escherichia coli APEC O1], gi\|115515...	598.0	[0..1]	[665..1]
gi\|396418 - gi\|396418\|gb\|AAC43177.1\| ORF_f665 [Escherichia coli str. K-12 substr. MG1655] gi\|396418\|gb\|AAC... - ORF_f665 [Escherichia coli]	596.0	[0..1]	[665..1]
gi\|75197942 - gi\|75197942\|ref\|ZP_00708012.1\| COG2015: Alkyl sulfatase and related hydrolases [Escherichia coli HS]	595.0	[0..1]	[665..1]
gi\|81247836, gi\|... - gi\|82546425\|ref\|YP_410372.1\| hypothetical protein SBO_4115 [Shigella boydii Sb227], gi\|81247836\|gb\|A...	595.0	[0..1]	[665..1]

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Predicted Domain #1

Region A:
Residues: [1-665]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEIYMNNSRL FRLSRIVIAL TAASGMMVNT ANAKEEAKAA TQYTQQVNQN YAKSLPFSDR  60
   61 QDFDDAQRGF IAPLLDEGIL RDANGKVYYR ADDYKFDINA AAPETVNPSL WRQSQINGIS 120
  121 GLFKVTDKMY QVRGQDISNI TFVEGEKGII VIDPLVTPPA AKAALDLYFQ HRPQKPIVAV 180
  181 IYTHSHTDHY GGVKGIISEA DVKSGKVQVI APAGFMDEAI SENVLAGNIM SRRALYSYGL 240
  241 LLPHNAQGNV GNGLGVTLAT GDPSIIAPTK TIVRTGEKMI IDGLEFDFLM TPGSEAPAEM 300
  301 HFYIPALKAL CTAENATHTL HNFYTLRGAK TRDTSKWTEY LNETLDMWGN DAEVLFMPHT 360
  361 WPVWGNKHIN DYIGKYRDTI KYIHDQTLHL ANQGYTMNEI GDMIKLPPAL ANNWASRGYY 420
  421 GSVSHNARAV YNFYLGYYDG NPANLHPYGQ VEMGKRYVQA LGGSARVINL AQEANKQGDY 480
  481 RWSAELLKQV IAANPGDQVA KNLQANNFEQ LGYQAESATW RGFYLTGAKE LREGVHKFSH 540
  541 GTTGSPDTIR GMSVEMLFDF MAVRLDSAKA AGKNISLNFN MSNGDNLNLT LNDSVLNYRK 600
  601 TLQPQADASF YISREDLHAV LTGQAKMADL VKAKKAKIIG NGAKLEEIIA CLDNFDLWVN 660
  661 IVTPN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	153.0
Match:	2cfuA
Description:	No description for 2cfuA was found.

Predicted functions:

Term	Confidence	Notes
alkyl sulfatase activity	1.69609271133145	bayes_pls_golite062009
hydroxyacylglutathione hydrolase activity	1.565406918731	bayes_pls_golite062009
catalytic activity	0.941400907161877	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: