YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|7466944, gi\|8...
Organism:	Escherichia coli
Length:	294 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7466944, gi|8....

Description	E-value	Query Range	Subject Range
gi\|12517478, gi\|... - gi\|15803474\|ref\|NP_289507.1\| hypothetical protein Z4280 [Escherichia coli O157:H7 EDL933], gi\|125174... gi\|13363283 - gi\|13363283\|dbj\|BAB37234.1\| hypothetical protein [Escherichia coli O157:H7 str. Sakai] gi\|13363283 - gi\|13363283\|dbj\|BAB37234.1\| hypothetical protein [Escherichia coli O157:H7] gi\|209760206, gi... - pir\|\|F85950 hypothetical protein yggG [imported] - Escherichia coli (strain O157:H7, substrain EDL9...	235.0	[0..1]	[294..1]
gi\|73856970, gi\|... - gi\|74313493\|ref\|YP_311912.1\| hypothetical protein SSON_3090 [Shigella sonnei Ss046], gi\|73856970\|gb\|... gi\|82545440, gi\|... - gi\|82545440\|ref\|YP_409387.1\| hypothetical protein SBO_3053 [Shigella boydii Sb227], gi\|81246851\|gb\|A...	235.0	[0..1]	[294..1]
gi\|56480213, gi\|... - gi\|56480213\|ref\|NP_708700.2\| hypothetical protein SF2926 [Shigella flexneri 2a str. 301], gi\|5638376... gi\|30042506, gi\|... - gi\|30064249\|ref\|NP_838420.1\| hypothetical protein S3128 [Shigella flexneri 2a str. 2457T], gi\|300425...	235.0	[0..1]	[294..1]
gi\|115514289, gi... - gi\|117625165\|ref\|YP_854153.1\| putative metalloprotease YggG [Escherichia coli APEC O1], gi\|115514289...	234.0	[0..1]	[294..1]
gi\|110344677, gi... - gi\|110643085\|ref\|YP_670815.1\| putative metalloprotease YggG [Escherichia coli 536], gi\|110344677\|gb\|...	233.0	[0..1]	[294..1]
gi\|110806842, gi... - gi\|110806842\|ref\|YP_690362.1\| hypothetical protein SFV_2988 [Shigella flexneri 5 str. 8401], gi\|1106...	232.0	[0..1]	[294..32]
gi\|91212317, gi\|... - gi\|91212317\|ref\|YP_542303.1\| putative metalloprotease YggG [Escherichia coli UTI89], gi\|91073891\|gb\|... gi\|237706413, gi... - gi\|237706413\|ref\|ZP_04536894.1\| conserved hypothetical protein [Escherichia sp. 3_2_53FAA], gi\|22689... gi\|26249356, gi\|... - gi\|26249356\|ref\|NP_755396.1\| putative metalloprotease yggG [Escherichia coli CFT073], gi\|26109764\|gb...	232.0	[0..1]	[294..32]
gi\|16766378, gi\|... - gi\|16766378\|ref\|NP_461993.1\| putative Zn-dependent protease [Salmonella typhimurium LT2], gi\|1642162... gi\|29138981, gi\|... - gi\|29143347\|ref\|NP_806689.1\| hypothetical protein t2997 [Salmonella enterica subsp. enterica serovar... gi\|16504162, gi\|... - gi\|25512536\|pir\|\|AE0876 conserved hypothetical protein STY3237 [imported] - Salmonella enterica subs... gi\|16761860 - gi\|16761860\|ref\|NP_457477.1\| hypothetical protein STY3237 [Salmonella enterica subsp. enterica serov... gi\|238909877 - gi\|238909877\|ref\|ZP_04653714.1\| peptidase M48, Ste24p [Salmonella enterica subsp. enterica serovar T... lcl\|NC_016856.1_... - [gene=yggG] [protein=putative Zn-dependent protease] [protein_id=YP_005239222.1] [location=3257799..... gi\|214002390 - gi\|214002390\|ref\|ZP_03413125.1\| peptidase M48, Ste24p [Salmonella enterica subsp. enterica serovar T... gi\|205347073, gi... - gi\|205347073\|gb\|EDZ33704.1\| peptidase M48, Ste24p [Salmonella enterica subsp. enterica serovar Hadar... gi\|167553223, gi... - gi\|205322288\|gb\|EDZ10127.1\| peptidase M48, Ste24p [Salmonella enterica subsp. enterica serovar Saint... gi\|213850123 - gi\|213850123\|ref\|ZP_03381021.1\| peptidase M48, Ste24p [Salmonella enterica subsp. enterica serovar T... gi\|213648605 - gi\|213648605\|ref\|ZP_03378658.1\| peptidase M48, Ste24p [Salmonella enterica subsp. enterica serovar T... gi\|213581203 - gi\|213581203\|ref\|ZP_03363029.1\| peptidase M48, Ste24p [Salmonella enterica subsp. enterica serovar T... gi\|194406812, gi... - gi\|194448508\|ref\|YP_002047065.1\| peptidase M48, Ste24p [Salmonella enterica subsp. enterica serovar ...	205.0	[0..43]	[294..1]
gi\|62129222, gi\|... - gi\|62181589\|ref\|YP_218006.1\| putative Zn-dependent protease with chaperone function [Salmonella ente...	205.0	[0..43]	[294..1]
gi\|170082490, gi... - gi\|170082490\|ref\|YP_001731810.1\| peptidase [Escherichia coli str. K-12 substr. DH10B], gi\|169890325\|... EG11291 - Phe-Phe periplasmic metalloprotease, OM lipoprotein; low salt-inducible; Era-binding heat shock prot... gi\|238902058, gi... - gi\|238902058\|ref\|YP_002927854.1\| putative peptidase [Escherichia coli BW2952], gi\|238862796\|gb\|ACR64... YGGG_ECOLI - Putative metalloprotease yggG (EC 3.4.24.-) - Escherichia coli gi\|89109713, gi\|... - gi\|89109713\|ref\|AP_003493.1\| predicted peptidase [Escherichia coli str. K-12 substr. W3110], gi\|8567... gi\|253772224, gi... - gi\|253772224\|ref\|YP_003035055.1\| peptidase M48 Ste24p [Escherichia coli BL21(DE3)], gi\|253323268\|gb\|... EG11291 - Phe-Phe periplasmic metalloprotease, OM lipoprotein; low salt-inducible; Era-binding heat shock prot...	204.0	[0..43]	[294..1]

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Predicted Domain #1

Region A:
Residues: [1-105]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLACCAIYSP VRCAFPYTET ERRFTCKRRI FRIILTLCGR ENMKIRALLV AMSVATVLTG  60
   61 CQNMDSNGLL SSGAEAFQAY SLSDAQVKTL SDQACQEMDS KATIA

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.935	a.165.1	Myosin phosphatase inhibitor 17kDa protein, CPI-17
View	Download	0.853	d.14.1	Ribosomal protein S5 domain 2-like
View	Download	0.841	a.74.1	Cyclin-like
View	Download	0.836	a.74.1	Cyclin-like
View	Download	0.820	a.56.1	CO dehydrogenase ISP C-domain like

Predicted Domain #2

Region A:
Residues: [106-294]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PANSEYAKRL TTIANALGNN INGQPVNYKV YMAKDVNAFA MANGCIRVYS GLMDMMTDNE  60
   61 VEAVIGHEMG HVALGHVKKG MQVALGTNAV RVAAASAGGI VGSLSQSQLG NLGEKLVNSQ 120
  121 FSQRQEAEAD DYSYDLLRQR GISPAGLATS FEKLAKLEEG RQSSMFDDHP ASAERAQHIR 180
  181 DRMSADGIK

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.07
Match:	1dmtA
Description:	Neutral endopeptidase (neprilysin)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.313713481761242	bayes_pls_golite062009
hydrolase activity	0.0940978605930549	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: