YRC Public Data Repository - Protein Structure Prediction

Protein:	ISPD_ECOLI
Organism:	Escherichia coli
Length:	236 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ISPD_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|49529346, gi\|... - gi\|50083370\|ref\|YP_044880.1\| dTDP-glucose pyrophosphorylase (glucose-1-phosphate thymidylyltransfera...	210.0	[0..2]	[234..1]
gi\|71906877, gi\|... - gi\|71906877\|ref\|YP_284464.1\| glucose-1-phosphate thymidylyltransferase [Dechloromonas aromatica RCB]...	209.0	[0..1]	[234..1]
gi\|45250012 - gi\|45250012\|gb\|AAS55725.1\| glucose-1-phosphate thymidyltransferase [Aneurinibacillus thermoaerophilu...	207.0	[0..9]	[234..2]
gi\|120605049, gi... - gi\|121592969\|ref\|YP_984865.1\| glucose-1-phosphate thymidylyltransferase [Acidovorax sp. JS42], gi\|12...	207.0	[0..5]	[234..1]
gi\|34811708, gi\|... - gi\|34811708\|pdb\|1H5S\|B Chain B, Thymidylyltransferase Complexed With Tmp, gi\|21466153\|pdb\|1H5T\|B Cha...	206.0	[0..5]	[234..1]
gi\|71065771, gi\|... - gi\|71065771\|ref\|YP_264498.1\| glucose-1-phosphate thymidylyltransferase [Psychrobacter arcticus 273-4...	205.0	[0..1]	[234..1]
gi\|46985 - gi\|46985\|emb\|CAA43074.1\| glucose-1-phosphate thymidylyltransferase [Salmonella enterica] gi\|96668 - pir\|\|S23342 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) [validated] - Salmonella cholera... RMLA_SALAN - Glucose-1-phosphate thymidylyltransferase OS=Salmonella anatum GN=rmlA PE=3 SV=1	205.0	[0..5]	[234..1]
gi\|197361929, gi... - gi\|197361929\|ref\|YP_002141566.1\| TDP-glucose pyrophosphorylase [Salmonella enterica subsp. enterica ... gi\|56127258, gi\|... - gi\|56413001\|ref\|YP_150076.1\| TDP-glucose pyrophosphorylase [Salmonella enterica subsp. enterica sero...	205.0	[0..5]	[234..1]
gi\|9957852 - gi\|9957852\|gb\|AAG09528.1\|AF279622_3 glucose-1-phosphate thymidylyltransferase [Salmonella enterica]	205.0	[0..5]	[234..1]

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Predicted Domain #1

Region A:
Residues: [1-236]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATTHLDVCA VVPAAGFGRR MQTECPKQYL SIGNQTILEH SVHALLAHPR VKRVVIAISP  60
   61 GDSRFAQLPL ANHPQITVVD GGDERADSVL AGLKAAGDAQ WVLVHDAARP CLHQDDLARL 120
  121 LALSETSRTG GILAAPVRDT MKRAEPGKNA IAHTVDRNGL WHALTPQFFP RELLHDCLTR 180
  181 ALNEGATITD EASALEYCGF HPQLVEGRAD NIKVTRPEDL ALAEFYLTRT IHQENT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	48.522879
Match:	1i52A
Description:	4-diphosphocytidyl-2-c-methylerythritol (CDP-me) synthase (YgbP)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity	2.01680144494637	bayes_pls_golite062009
catalytic activity	1.88676710996045	bayes_pls_golite062009
transferase activity	1.47184463413038	bayes_pls_golite062009
nucleotidyltransferase activity	1.03393419806381	bayes_pls_golite062009
cytidylyltransferase activity	0.983416157001861	bayes_pls_golite062009
transferase activity, transferring hexosyl groups	0.651454753851031	bayes_pls_golite062009
UDP-glycosyltransferase activity	0.423789091098118	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.361674579616957	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: