YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|49176236, gi\|...
Organism:	Escherichia coli K-12
Length:	293 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|49176236, gi|....

Description	E-value	Query Range	Subject Range
gi\|115513886, gi... - gi\|117624762\|ref\|YP_853675.1\| putative peptidase [Escherichia coli APEC O1], gi\|115513886\|gb\|ABJ0196... gi\|218559460, gi... - gi\|218559460\|ref\|YP_002392373.1\| putative peptidase [Escherichia coli S88], gi\|218366229\|emb\|CAR0397... gi\|237705045, gi... - gi\|237705045\|ref\|ZP_04535526.1\| conserved hypothetical protein [Escherichia sp. 3_2_53FAA], gi\|22690... gi\|91073435, gi\|... - gi\|91211861\|ref\|YP_541847.1\| hypothetical protein UTI89_C2856 [Escherichia coli UTI89], gi\|91073435\|...	210.0	[0..1]	[293..1]
gi\|74313060, gi\|... - gi\|74313060\|ref\|YP_311479.1\| putative enzyme [Shigella sonnei Ss046], gi\|73856537\|gb\|AAZ89244.1\| put... gi\|81246394, gi\|... - gi\|82544983\|ref\|YP_408930.1\| putative enzyme [Shigella boydii Sb227], gi\|81246394\|gb\|ABB67102.1\| put...	210.0	[0..1]	[293..1]
gi\|209763200, gi... - gi\|25356173\|pir\|\|C85898 probable proteinase (EC 3.4.-.-) Z3802 [imported] - Escherichia coli (strain... gi\|15803060, gi\|... - gi\|15803060\|ref\|NP_289090.1\| putative hydrolase [Escherichia coli O157:H7 EDL933], gi\|12516937\|gb\|AA... YHFR_ECO57 - Uncharacterized protein yfhR OS=Escherichia coli O157:H7 GN=yhfR PE=3 SV=3 gi\|13362871 - gi\|13362871\|dbj\|BAB36823.1\| putative enzyme [Escherichia coli O157:H7 str. Sakai]	210.0	[0..1]	[293..1]
gi\|81242065, gi\|... - gi\|82777917\|ref\|YP_404266.1\| putative enzyme [Shigella dysenteriae Sd197], gi\|81242065\|gb\|ABB62775.1...	209.0	[0..1]	[293..1]
gi\|227887570, gi... - gi\|227887570\|ref\|ZP_04005375.1\| lipoprotein [Escherichia coli 83972], gi\|227835920\|gb\|EEJ46386.1\| li... gi\|26248902, gi\|... - gi\|26248902\|ref\|NP_754942.1\| hypothetical protein c3060 [Escherichia coli CFT073], gi\|26109308\|gb\|AA...	208.0	[0..1]	[293..1]
gi\|192958343, gi... - gi\|75237720\|ref\|ZP_00721736.1\| COG1073: Hydrolases of the alpha/beta superfamily [Escherichia coli E... gi\|194427348, gi... - gi\|75211500\|ref\|ZP_00711590.1\| COG1073: Hydrolases of the alpha/beta superfamily [Escherichia coli B... gi\|75196551, gi\|... - gi\|75196551\|ref\|ZP_00706621.1\| COG1073: Hydrolases of the alpha/beta superfamily [Escherichia coli H... gi\|157155268, gi... - gi\|75187286\|ref\|ZP_00700553.1\| COG1073: Hydrolases of the alpha/beta superfamily [Escherichia coli E... gi\|83586816, gi\|... - gi\|83586816\|ref\|ZP_00925447.1\| COG1073: Hydrolases of the alpha/beta superfamily [Escherichia coli 1... gi\|253323614, gi... - gi\|253772570\|ref\|YP_003035401.1\| putative enzyme [Escherichia coli BL21(DE3)], gi\|253323614\|gb\|ACT28... gi\|75515873, gi\|... - gi\|75515873\|ref\|ZP_00738008.1\| COG1073: Hydrolases of the alpha/beta superfamily [Escherichia coli 5...	198.0	[0..10]	[293..1]
gi\|38704101 - gi\|38704101\|ref\|NP_311427.2\| hypothetical protein ECs3400 [Escherichia coli O157:H7 str. Sakai] gi\|217327871, gi... - gi\|217327871\|ref\|ZP_03443954.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. TW1458... gi\|209160301, gi... - gi\|209398901\|ref\|YP_002272009.1\| hypothetical protein ECH74115_3766 [Escherichia coli O157:H7 str. E... gi\|168798912, gi... - gi\|189378678\|gb\|EDU97094.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC508], gi... gi\|168787887, gi... - gi\|189372356\|gb\|EDU90772.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC869], gi... gi\|189003245, gi... - gi\|189003245\|gb\|EDU72231.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4076], g... gi\|168773544, gi... - gi\|187770583\|gb\|EDU34427.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4196], g... gi\|208738596, gi... - gi\|208818473\|ref\|ZP_03258793.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4042... gi\|208813875, gi... - gi\|208813875\|ref\|ZP_03255204.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4045... gi\|208727597, gi... - gi\|208807796\|ref\|ZP_03250133.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4206... gi\|254593884, gi... - gi\|254794484\|ref\|YP_003079321.1\| predicted peptidase [Escherichia coli O157:H7 str. TW14359], gi\|254... gi\|195936681 - gi\|195936681\|ref\|ZP_03082063.1\| hypothetical protein EscherichcoliO157_09495 [Escherichia coli O157:... YHFR_ECO57 - Uncharacterized protein YfhR OS=Escherichia coli O157:H7 GN=yhfR PE=3 SV=4 gi\|189362267, gi... - gi\|189362267\|gb\|EDU80686.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4486], g... gi\|189368380, gi... - gi\|189368380\|gb\|EDU86796.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501], g... gi\|189355307, gi... - gi\|189355307\|gb\|EDU73726.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4401], g... gi\|168748400, gi... - gi\|188017106\|gb\|EDU55228.1\| conserved hypothetical protein [Escherichia coli O157:H7 str. EC4113], g...	198.0	[0..10]	[293..1]
gi\|194419697, gi... - gi\|83570754\|ref\|ZP_00922197.1\| COG1073: Hydrolases of the alpha/beta superfamily [Shigella dysenteri...	197.0	[0..10]	[293..1]
gi\|75178140, gi\|... - gi\|75178140\|ref\|ZP_00698199.1\| COG1073: Hydrolases of the alpha/beta superfamily [Shigella boydii BS...	197.0	[0..10]	[293..1]
gi\|75240441, gi\|... - gi\|75240441\|ref\|ZP_00724375.1\| COG1073: Hydrolases of the alpha/beta superfamily [Escherichia coli F... gi\|110642699, gi... - gi\|110642699\|ref\|YP_670429.1\| hypothetical protein ECP_2539 [Escherichia coli 536], gi\|110344291\|gb\|...	197.0	[0..10]	[293..1]

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Predicted Domain #1

Region A:
Residues: [1-293]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIKKSQGKVM ALPVNKRVPK ILFILFVVAF CVYLVPRVAI NFFYYPDDKI YGPDPWSAES  60
   61 VEFTAKDGTR LQGWFIPSST GPADNAIATI IHAHGNAGNM SAHWPLVSWL PERNFNVFMF 120
  121 DYRGFGKSKG TPSQAGLLDD TQSAINVVRH RSDVNPQRLV LFGQSIGGAN ILDVIGRGDR 180
  181 EGIRAVILDS TFASYATIAN QMIPGSGYLL DESYSGENYI ASVSPIPLLL IHGKADHVIP 240
  241 WQHSEKLYSL AKEPKRLILI PDGEHIDAFS DRHGDVYREQ MVDFILSALN PQN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	33.522879
Match:	1e5tA
Description:	Prolyl oligopeptidase, N-terminal domain; Prolyl oligopeptidase, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.629869101256762	bayes_pls_golite062009
hydrolase activity	0.512422589119661	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: