YRC Public Data Repository - Protein Structure Prediction

Protein:	EG10148
Organism:	Escherichia coli K-12
Length:	286 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EG10148.

Description	E-value	Query Range	Subject Range
gi\|110343593, gi... - gi\|110642001\|ref\|YP_669731.1\| chemotaxis methyltransferase CheR [Escherichia coli 536], gi\|110343593... gi\|191173021, gi... - gi\|191173021\|ref\|ZP_03034555.1\| chemotaxis protein methyltransferase CheR [Escherichia coli F11], gi... gi\|215487096, gi... - gi\|215487096\|ref\|YP_002329527.1\| chemotaxis methyltransferase CheR [Escherichia coli O127:H6 str. E2...	308.0	[0..1]	[286..1]
gi\|117624035, gi... - gi\|117624035\|ref\|YP_852948.1\| chemotaxis methyltransferase CheR [Escherichia coli APEC O1], gi\|11551... gi\|218558748, gi... - gi\|218558748\|ref\|YP_002391661.1\| chemotaxis methyltransferase CheR [Escherichia coli S88], gi\|218365... gi\|218689881, gi... - gi\|218689881\|ref\|YP_002398093.1\| chemotaxis methyltransferase CheR [Escherichia coli ED1a], gi\|21842... gi\|218369531, gi... - gi\|218699545\|ref\|YP_002407174.1\| chemotaxis methyltransferase CheR [Escherichia coli IAI39], gi\|2183... gi\|237705840, gi... - gi\|237705840\|ref\|ZP_04536321.1\| chemotaxis regulator [Escherichia sp. 3_2_53FAA], gi\|226900597\|gb\|EE... gi\|91211109, gi\|... - gi\|91211109\|ref\|YP_541095.1\| chemotaxis methyltransferase CheR [Escherichia coli UTI89], gi\|91072683...	308.0	[0..1]	[286..1]
gi\|145523 - gi\|145523\|gb\|AAA23568.1\| cheR protein [Escherichia coli]	307.0	[0..1]	[286..1]
gi\|26248151, gi\|... - gi\|26248151\|ref\|NP_754191.1\| chemotaxis methyltransferase CheR [Escherichia coli CFT073], gi\|2610855...	307.0	[0..1]	[286..1]
gi\|13362062, gi\|... - gi\|15831848\|ref\|NP_310621.1\| chemotaxis methyltransferase CheR [Escherichia coli O157:H7 str. Sakai]... gi\|217317950, gi... - gi\|217328603\|ref\|ZP_03444684.1\| chemotaxis protein methyltransferase CheR [Escherichia coli O157:H7 ... gi\|209400250, gi... - gi\|209400250\|ref\|YP_002270968.1\| chemotaxis protein methyltransferase CheR [Escherichia coli O157:H7... gi\|254793508, gi... - gi\|254793508\|ref\|YP_003078345.1\| chemotaxis regulator, protein-glutamate methyltransferase [Escheric... gi\|189376034, gi... - gi\|189376034\|gb\|EDU94450.1\| chemotaxis protein methyltransferase CheR [Escherichia coli O157:H7 str.... gi\|189370693, gi... - gi\|189370693\|gb\|EDU89109.1\| chemotaxis protein methyltransferase CheR [Escherichia coli O157:H7 str.... gi\|188999442, gi... - gi\|188999442\|gb\|EDU68428.1\| chemotaxis protein methyltransferase CheR [Escherichia coli O157:H7 str.... gi\|168776565, gi... - gi\|187768093\|gb\|EDU31937.1\| chemotaxis protein methyltransferase CheR [Escherichia coli O157:H7 str.... gi\|209767260, gi... - pir\|\|F85801 response regulator for chemotaxis [imported] - Escherichia coli (strain O157:H7, substra... gi\|208740236, gi... - gi\|208820113\|ref\|ZP_03260433.1\| chemotaxis protein methyltransferase CheR [Escherichia coli O157:H7 ... gi\|208731245, gi... - gi\|208816902\|ref\|ZP_03258022.1\| chemotaxis protein methyltransferase CheR [Escherichia coli O157:H7 ... gi\|15802296, gi\|... - gi\|15802296\|ref\|NP_288321.1\| chemotaxis methyltransferase CheR [Escherichia coli O157:H7 EDL933], gi... gi\|208810789, gi... - gi\|208810789\|ref\|ZP_03252665.1\| chemotaxis protein methyltransferase CheR [Escherichia coli O157:H7 ... gi\|13362062, gi\|... - gi\|15831848\|ref\|NP_310621.1\| response regulator for chemotaxis [Escherichia coli O157:H7], gi\|133620... gi\|195939588 - gi\|195939588\|ref\|ZP_03084970.1\| chemotaxis methyltransferase CheR [Escherichia coli O157:H7 str. EC4... gi\|189360321, gi... - gi\|189360321\|gb\|EDU78740.1\| chemotaxis protein methyltransferase CheR [Escherichia coli O157:H7 str.... gi\|189367346, gi... - gi\|189367346\|gb\|EDU85762.1\| chemotaxis protein methyltransferase CheR [Escherichia coli O157:H7 str.... gi\|189355173, gi... - gi\|189355173\|gb\|EDU73592.1\| chemotaxis protein methyltransferase CheR [Escherichia coli O157:H7 str.... gi\|188017379, gi... - gi\|188017379\|gb\|EDU55501.1\| chemotaxis protein methyltransferase CheR [Escherichia coli O157:H7 str....	306.0	[0..1]	[286..1]
gi\|30041588, gi\|... - gi\|30063336\|ref\|NP_837507.1\| chemotaxis methyltransferase CheR [Shigella flexneri 2a str. 2457T], gi... gi\|24113269, gi\|... - gi\|24113269\|ref\|NP_707779.1\| chemotaxis methyltransferase CheR [Shigella flexneri 2a str. 301], gi\|2...	305.0	[0..1]	[286..1]
CHER_SALTY - Chemotaxis protein methyltransferase OS=Salmonella typhimurium GN=cheR PE=1 SV=1 CHER_SALTY - Chemotaxis protein methyltransferase OS=Salmonella typhimurium GN=cheR PE=1 SV=1 gi\|62180495, gi\|... - gi\|62180495\|ref\|YP_216912.1\| chemotaxis methyltransferase CheR [Salmonella enterica subsp. enterica ... gi\|56413162, gi\|... - gi\|56413162\|ref\|YP_150237.1\| chemotaxis methyltransferase CheR [Salmonella enterica subsp. enterica ... gi\|206708364, gi... - gi\|207856561\|ref\|YP_002243212.1\| chemotaxis methyltransferase CheR [Salmonella enterica subsp. enter... lcl\|NC_016856.1_... - [gene=cheR] [protein=chemotaxis methyltransferase CheR] [protein_id=YP_005237886.1] [location=comple... gi\|197243583, gi... - gi\|197265328\|ref\|ZP_03165402.1\| chemotaxis protein methyltransferase CheR [Salmonella enterica subsp... gi\|194446749, gi... - gi\|194446749\|ref\|YP_002041184.1\| chemotaxis protein methyltransferase CheR [Salmonella enterica subs... gi\|168462547, gi... - gi\|195634579\|gb\|EDX52931.1\| chemotaxis protein methyltransferase CheR [Salmonella enterica subsp. en... gi\|161362886, gi... - gi\|161613522\|ref\|YP_001587487.1\| chemotaxis methyltransferase CheR [Salmonella enterica subsp. enter... gi\|205360297, gi... - gi\|205360297\|ref\|ZP_02681776.2\| chemotaxis protein methyltransferase CheR [Salmonella enterica subsp... CHER_SALTY - Chemotaxis protein methyltransferase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)... gi\|205327862, gi... - gi\|205358057\|ref\|ZP_02575316.2\| chemotaxis protein methyltransferase CheR [Salmonella enterica subsp... gi\|200390528, gi... - gi\|200390528\|ref\|ZP_03217139.1\| chemotaxis protein methyltransferase CheR [Salmonella enterica subsp... gi\|197362088, gi... - gi\|197362088\|ref\|YP_002141725.1\| chemotaxis methyltransferase CheR [Salmonella enterica subsp. enter...	304.0	[0..1]	[286..1]
gi\|10566571 - gi\|10566571\|dbj\|BAB15839.1\| CheR [Enterobacter cloacae]	304.0	[0..1]	[286..1]
gi\|110615412, gi... - gi\|110805864\|ref\|YP_689384.1\| chemotaxis methyltransferase CheR [Shigella flexneri 5 str. 8401], gi\|...	304.0	[0..1]	[286..1]
gi\|91776284, gi\|... - gi\|91776284\|ref\|YP_546040.1\| MCP methyltransferase, CheR-type [Methylobacillus flagellatus KT], gi\|9...	302.0	[0..19]	[285..14]

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Predicted Domain #1

Region A:
Residues: [1-286]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSSLPCGQT SLLLQMTERL ALSDAHFRRI SQLIYQRAGI VLADHKRDMV YNRLVRRLRS  60
   61 LGLTDFGHYL NLLESNQHSG EWQAFINSLT TNLTAFFREA HHFPLLADHA RRRSGEYRVW 120
  121 SAAASTGEEP YSIAMTLADT LGTAPGRWKV FASDIDTEVL EKARSGIYRH EELKNLTPQQ 180
  181 LQRYFMRGTG PHEGLVRVRQ ELANYVDFAP LNLLAKQYTV PGPFDAIFCR NVMIYFDQTT 240
  241 QQEILRRFVP LLKPDGLLFA GHSENFSHLE RRFTLRGQTV YALSKD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	79.09691
Match:	1af7A
Description:	CHER FROM SALMONELLA TYPHIMURIUM
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transferase activity	1.05424873310521	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	0.854425465362466	bayes_pls_golite062009
O-methyltransferase activity	0.85422125054835	bayes_pls_golite062009
methyltransferase activity	0.84003681899004	bayes_pls_golite062009
protein-glutamate O-methyltransferase activity	0.5118916412645	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	0.266076794310504	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: