YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|209746094, gi...
Organism:	Escherichia coli
Length:	454 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|209746094, gi....

Description	E-value	Query Range	Subject Range
gi\|30039945, gi\|... - gi\|30061703\|ref\|NP_835874.1\| poly(A) polymerase I [Shigella flexneri 2a str. 2457T], gi\|30039945\|gb\|... gi\|56383162, gi\|... - gi\|56479611\|ref\|NP_706091.2\| poly(A) polymerase I [Shigella flexneri 2a str. 301], gi\|56383162\|gb\|AA...	411.0	[0..1]	[433..1]
gi\|193067681, gi... - gi\|75238848\|ref\|ZP_00722830.1\| COG0617: tRNA nucleotidyltransferase/poly(A) polymerase [Escherichia ...	410.0	[0..1]	[433..1]
gi\|75194355, gi\|... - gi\|75194355\|ref\|ZP_00704425.1\| COG0617: tRNA nucleotidyltransferase/poly(A) polymerase [Escherichia ... gi\|75189240, gi\|... - gi\|75189240\|ref\|ZP_00702507.1\| COG0617: tRNA nucleotidyltransferase/poly(A) polymerase [Escherichia ...	410.0	[0..1]	[433..1]
gi\|253976373, gi... - gi\|254287066\|ref\|YP_003052814.1\| poly(A) polymerase I [Escherichia coli BL21(DE3)], gi\|253976373\|gb\|... gi\|253972164, gi... - gi\|254160263\|ref\|YP_003043371.1\| poly(A) polymerase I [Escherichia coli B str. REL606], gi\|253972164... gi\|194421918, gi... - gi\|83585460\|ref\|ZP_00924105.1\| COG0617: tRNA nucleotidyltransferase/poly(A) polymerase [Escherichia ...	410.0	[0..1]	[433..1]
PCNB_ECOL6 - (P0ABF2) Poly(A) polymerase (EC 2.7.7.19) (PAP) (Plasmid copy number protein) gi\|82542743, gi\|... - gi\|82542743\|ref\|YP_406690.1\| poly(A) polymerase I [Shigella boydii Sb227], gi\|81244154\|gb\|ABB64862.1... gi\|209917334, gi... - gi\|209917334\|ref\|YP_002291418.1\| poly(A) polymerase I [Escherichia coli SE11], gi\|209910593\|dbj\|BAG7... gi\|162139816 - gi\|162139816\|ref\|NP_308174.2\| poly(A) polymerase I [Escherichia coli O157:H7 str. Sakai] gi\|161986592 - gi\|161986592\|ref\|YP_309183.2\| poly(A) polymerase I [Shigella sonnei Ss046] tr\|A0A0G3HX71\|A0... - Poly(A) polymerase I OS=Escherichia coli (strain K12) GN=pcnB PE=3 SV=2 gi\|26246087, gi\|... - gi\|26246087\|ref\|NP_752126.1\| poly(A) polymerase I [Escherichia coli CFT073], gi\|26106484\|gb\|AAN78670... PCNB_ECO57 - (P0ABF3) Poly(A) polymerase (EC 2.7.7.19) (PAP) (Plasmid copy number protein) gi\|218368550, gi... - gi\|218698564\|ref\|YP_002406193.1\| poly(A) polymerase I [Escherichia coli IAI39], gi\|218368550\|emb\|CAR... gi\|218688020, gi... - gi\|218688020\|ref\|YP_002396232.1\| poly(A) polymerase I [Escherichia coli ED1a], gi\|218425584\|emb\|CAR0... gi\|218363855, gi... - gi\|218557086\|ref\|YP_002389999.1\| poly(A) polymerase I [Escherichia coli S88], gi\|218363855\|emb\|CAR01... gi\|254037561, gi... - gi\|254037561\|ref\|ZP_04871638.1\| poly(A) polymerase I [Escherichia sp. 1_1_43], gi\|226840667\|gb\|EEH72... PCNB_ECOLI - (P0ABF1) Poly(A) polymerase (EC 2.7.7.19) (PAP) (Plasmid copy number protein) gi\|226902214, gi... - gi\|237704302\|ref\|ZP_04534783.1\| poly(A) polymerase I [Escherichia sp. 3_2_53FAA], gi\|226902214\|gb\|EE... gi\|110341956, gi... - gi\|110640364\|ref\|YP_668092.1\| poly(A) polymerase I [Escherichia coli 536], gi\|110341956\|gb\|ABG68193....	410.0	[0..1]	[433..19]
gi\|82775535, gi\|... - gi\|82775535\|ref\|YP_401882.1\| poly(A) polymerase I [Shigella dysenteriae Sd197], gi\|81239683\|gb\|ABB60...	410.0	[0..1]	[433..1]
gi\|110613746, gi... - gi\|110804198\|ref\|YP_687718.1\| poly(A) polymerase I [Shigella flexneri 5 str. 8401], gi\|110613746\|gb\|...	410.0	[0..1]	[433..1]
gi\|25497051 - gi\|25497051\|pir\|\|C85498 poly(A) polymerase I [imported] - Escherichia coli (strain O157:H7, substrai... gi\|15799827, gi\|... - gi\|15799827\|ref\|NP_285839.1\| poly(A) polymerase I [Escherichia coli O157:H7 EDL933], gi\|12512861\|gb\|...	409.0	[0..1]	[433..1]
gi\|254791278, gi... - gi\|254791278\|ref\|YP_003076115.1\| poly(A) polymerase I [Escherichia coli O157:H7 str. TW14359], gi\|25... gi\|238862072, gi... - gi\|238899542\|ref\|YP_002925338.1\| poly(A) polymerase I [Escherichia coli BW2952], gi\|238862072\|gb\|ACR... gi\|85674351, gi\|... - gi\|89107024\|ref\|AP_000804.1\| poly(A) polymerase I [Escherichia coli str. K-12 substr. W3110], gi\|856... EG10690 - poly(A) polymerase / Poly(A) polymerase; controls plasmid copy number; rare AUU start codon, growth-... PCNB_ECO57 - Poly(A) polymerase I OS=Escherichia coli O157:H7 GN=pcnB PE=3 SV=2 PCNB_ECOL6 - Poly(A) polymerase OS=Escherichia coli O6 GN=pcnB PE=3 SV=2 EG10690 - poly(A) polymerase / Poly(A) polymerase; controls plasmid copy number; rare AUU start codon, growth-... gi\|170079780, gi... - gi\|170079780\|ref\|YP_001729100.1\| poly(A) polymerase I [Escherichia coli str. K-12 substr. DH10B], gi... PCNB_ECOLI - Poly(A) polymerase (EC 2.7.7.19) (PAP) (Plasmid copy number protein) - Escherichia coli PCNB_ECOL6 - Poly(A) polymerase I OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=pcnB PE=3 SV=...	409.0	[0..1]	[433..12]
gi\|91209212, gi\|... - gi\|91209212\|ref\|YP_539198.1\| poly(A) polymerase I [Escherichia coli UTI89], gi\|91070786\|gb\|ABE05667....	408.0	[0..1]	[433..19]

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Predicted Domain #1

Region A:
Residues: [1-382]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSREESEAE QAVARPQVTV IPREQHAISR KDISENALKV MYRLNKAGYE AWLVGGGVRD  60
   61 LLLGKKPKDF DVTTNATPEQ VRKLFRNCRL VGRRFRLAHV MFGPEIIEVA TFRGHHEGNV 120
  121 SDRTTSQRGQ NGMLLRDNIF GSIEEDAQRR DFTINSLYYS VADFTVRDYV GGMKDLKDGV 180
  181 IRLIGNPETR YREDPVRMLR AVRFAAKLGM RISPETAEPI PRLATLLNDI PPARLFEESL 240
  241 KLLQAGYGYE TYKLLCEYHL FQPLFPTITR YFTENGDSPM ERIIEQVLKN TDTRIHNDMR 300
  301 VNPAFLFAAM FWYPLLETAQ KIAQESGLTY HDAFALAMND VLDEACRSLA IPKRLTTLTR 360
  361 DIWQLQLRMS RRQGKRAWKL LE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	60.0
Match:	1ou5A
Description:	tRNA CCA-adding enzyme, C-terminal domains; tRNA CCA-adding enzyme, head domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transferase activity, transferring phosphorus-containing groups	2.13977436268217	bayes_pls_golite062009
RNA binding	1.95446539797934	bayes_pls_golite062009
transferase activity	1.58185056077551	bayes_pls_golite062009
nucleotidyltransferase activity	1.28424599869932	bayes_pls_golite062009
catalytic activity	0.75232920999699	bayes_pls_golite062009
polynucleotide adenylyltransferase activity	0.747086661208511	bayes_pls_golite062009
tRNA binding	0.671378805940772	bayes_pls_golite062009
nucleic acid binding	0.56250895409788	bayes_pls_golite062009
binding	0.248197954076327	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [383-454]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HPKFRAAYDL LALRAEVERN AELQRLVKWW GEFQVSAPPD QKGMLNELDE EPSPRRRTRR  60
   61 PRKRAPRREG TA

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: