YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|25331550
Organism:	Clostridium acetobutylicum
Length:	219 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|25331550.

Description	E-value	Query Range	Subject Range
gi\|146273747, gi... - gi\|98662370\|dbj\|GAA00697.1\| unnamed protein product [Pelotomaculum thermopropionicum SI], gi\|1476776...	197.0	[0..1]	[202..1]
gi\|134299758, gi... - gi\|88944800\|ref\|ZP_01148024.1\| Phosphoglycerate mutase/fructose-2,6-bisphosphatase [Desulfotomaculum...	197.0	[0..2]	[202..3]
gi\|149903058, gi... - gi\|82748754\|ref\|ZP_00911232.1\| possible phosphoglycerate mutase [Clostridium beijerincki NCIMB 8052]...	191.0	[0..1]	[203..1]
gi\|51950293, gi\|... - gi\|51950293\|gb\|AAH82455.1\| MGC84250 protein [Xenopus laevis], gi\|148225296\|ref\|NP_001087906.1\| MGC84...	188.0	[0..1]	[217..1]
gi\|46229585 - gi\|46229585\|gb\|EAK90403.1\| glycolytic phosphoglycerate mutase [Cryptosporidium parvum Iowa II] gi\|66363230 - gi\|66363230\|ref\|XP_628581.1\| glycolytic phosphoglycerate mutase [Cryptosporidium parvum Iowa II]	187.0	[0..1]	[217..1]
gi\|67624535 - gi\|67624535\|ref\|XP_668550.1\| phosphoglycerate mutase [Cryptosporidium hominis TU502] gi\|54659749 - gi\|54659749\|gb\|EAL38313.1\| phosphoglycerate mutase [Cryptosporidium hominis]	187.0	[0..1]	[217..1]
gi\|54020839, gi\|... - gi\|54020839\|ref\|NP_001005665.1\| bisphosphoglycerate mutase 1 [Xenopus (Silurana) tropicalis], gi\|492...	185.0	[0..1]	[217..1]
gi\|83572867, gi\|... - gi\|83589953\|ref\|YP_429962.1\| phosphoglycerate mutase [Moorella thermoacetica ATCC 39073], gi\|8357286...	185.0	[0..2]	[205..3]
gi\|47212179 - gi\|47212179\|emb\|CAF95127.1\| unnamed protein product [Tetraodon nigroviridis]	185.0	[0..1]	[217..1]

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Predicted Domain #1

Region A:
Residues: [1-219]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTTVLLVRH GETEWNVQGR FQGCHDINLT DNGIEQAKRV AKRLEGSFDC VYASPLKRAF  60
   61 NTAKLIASTK GISPIIEDDL REINFGLWEG LTIKEMKSKF PKEFDIWRND TEDGPLCGGD 120
  121 LSIKRASIRV EHAVLKIVND NKGKNIVVVA HGGIIKAALI ALFNWNMAMY HRILLGNTSI 180
  181 CKIEFNENNI PKIVTINDVS HLPEEYAEKD PMHDKKEIV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	46.154902
Match:	1xq9A
Description:	Structure of Phosphoglycerate Mutase from Plasmodium falciparum at 2.6 Resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phosphoglycerate mutase activity	3.38777226675734	bayes_pls_golite062009
phosphofructokinase activity	3.23286891159765	bayes_pls_golite062009
fructose-2,6-bisphosphate 2-phosphatase activity	2.79017097989614	bayes_pls_golite062009
6-phosphofructo-2-kinase activity	2.66778782568695	bayes_pls_golite062009
carbohydrate kinase activity	1.86382423322759	bayes_pls_golite062009
carbohydrate phosphatase activity	1.56016941506609	bayes_pls_golite062009
catalytic activity	1.37714494241232	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	1.05740895199147	bayes_pls_golite062009
hydrolase activity	0.959714350381009	bayes_pls_golite062009
intramolecular transferase activity, phosphotransferases	0.916759493094631	bayes_pls_golite062009
binding	0.911287540615709	bayes_pls_golite062009
isomerase activity	0.275500708652009	bayes_pls_golite062009
phosphatase activity	0.265410208825198	bayes_pls_golite062009
phosphoric ester hydrolase activity	0.211236676964713	bayes_pls_golite062009
intramolecular transferase activity	0.17180601190736	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: