YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|15896218, gi\|...
Organism:	Clostridium acetobutylicum ATCC 824
Length:	104 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|15896218, gi|....

Description	E-value	Query Range	Subject Range
gi\|147922098, gi... - gi\|148985794\|ref\|ZP_01818922.1\| PTS system, lactose-specific IIA component [Streptococcus pneumoniae... gi\|183576574, gi... - gi\|183576574\|gb\|EDT97102.1\| lactose-specific phosphotransferase enzyme iia component (pts system lac... gi\|183577168, gi... - gi\|183577168\|gb\|EDT97696.1\| lactose-specific phosphotransferase enzyme iia component (pts system lac... gi\|183572551, gi... - gi\|183572551\|gb\|EDT93079.1\| lactose-specific phosphotransferase enzyme iia component (pts system lac... gi\|168491109, gi... - gi\|183574521\|gb\|EDT95049.1\| lactose-specific phosphotransferase enzyme iia component (pts system lac... gi\|116077175, gi... - gi\|116516599\|ref\|YP_816522.1\| PTS system, lactose-specific IIA component [Streptococcus pneumoniae D... gi\|172043544, gi... - gi\|172043544\|gb\|EDT51590.1\| lactose-specific phosphotransferase enzyme iia component (pts system lac... gi\|168486510, gi... - gi\|183570441\|gb\|EDT90969.1\| lactose-specific phosphotransferase enzyme iia component (pts system lac... gi\|25287982 - pir\|\|F98005 PTS system, lactose-specific IIA component (EC 2.7.-.-) [imported] - Streptococcus pneum... gi\|15458693, gi\|... - gi\|15903114\|ref\|NP_358664.1\| PTS system, lactose-specific IIA component [Streptococcus pneumoniae R6... gi\|149026434, gi... - gi\|149026434\|ref\|ZP_01836571.1\| PTS system, lactose-specific IIA component [Streptococcus pneumoniae... gi\|147760391, gi... - gi\|149008152\|ref\|ZP_01831671.1\| PTS system, lactose-specific IIA component [Streptococcus pneumoniae... gi\|149004138, gi... - gi\|149004138\|ref\|ZP_01828941.1\| PTS system, lactose-specific IIA component [Streptococcus pneumoniae... gi\|148999049, gi... - gi\|148999049\|ref\|ZP_01826481.1\| PTS system, lactose-specific IIA component [Streptococcus pneumoniae... gi\|147926867, gi... - gi\|148995099\|ref\|ZP_01824006.1\| PTS system, lactose-specific IIA component [Streptococcus pneumoniae... gi\|148990442, gi... - gi\|148990442\|ref\|ZP_01821600.1\| PTS system, lactose-specific IIA component [Streptococcus pneumoniae... gi\|225724966, gi... - gi\|225856861\|ref\|YP_002738372.1\| lactose-specific phosphotransferase enzyme iia component (pts syste... gi\|225854658, gi... - gi\|225854658\|ref\|YP_002736170.1\| lactose-specific phosphotransferase enzyme iia component (pts syste... gi\|242245443, gi... - gi\|242245443\|ref\|ZP_04799880.1\| PTS system, lactose-specific IIA component [Streptococcus pneumoniae... gi\|237822459 - gi\|237822459\|ref\|ZP_04598304.1\| lactose-specific phosphotransferase enzyme iia component (pts system... gi\|237649550 - gi\|237649550\|ref\|ZP_04523802.1\| lactose-specific phosphotransferase enzyme iia component (pts system... gi\|225726993, gi... - gi\|225860972\|ref\|YP_002742481.1\| lactose-specific phosphotransferase enzyme iia component (pts syste... gi\|194398361, gi... - gi\|194398361\|ref\|YP_002037793.1\| PTS system, IIA component [Streptococcus pneumoniae G54], gi\|194358... gi\|221231894, gi... - gi\|221231894\|ref\|YP_002511046.1\| PTS system, lactose-specific IIA component [Streptococcus pneumonia... gi\|168995239, gi... - gi\|169832737\|ref\|YP_001694627.1\| lactose-specific phosphotransferase enzyme IIA component [Streptoco... gi\|182629414, gi... - gi\|182684080\|ref\|YP_001835827.1\| PTS system, lactose-specific IIA component [Streptococcus pneumonia...	134.0	[0..1]	[102..1]
PTLA_LACLL - Lactose-specific phosphotransferase enzyme IIA component OS=Lactococcus lactis subsp. lactis GN=lacF... gi\|97953, gi\|321... - pir\|\|A23696 phosphotransferase system enzyme III (EC 2.7.-.-) - Lactococcus lactis, gi\|3212515\|pdb\|...	134.0	[0..1]	[102..1]
gi\|25287975 - pir\|\|F95137 PTS system, lactose-specific IIA component [imported] - Streptococcus pneumoniae (strain... gi\|66877899, gi\|... - gi\|66877899\|ref\|ZP_00403415.1\| COG1447: Phosphotransferase system cellobiose-specific component IIA ...	134.0	[0..1]	[102..1]
gi\|76574895 - gi\|76574895\|gb\|ABA47365.1\| PTS system, lactose-specific IIA component [Lactococcus lactis] gi\|116326611, gi... - gi\|116326611\|ref\|YP_796531.1\| cellobiose-specific PTS system IIA component [Lactococcus lactis subsp...	134.0	[0..1]	[102..1]
gi\|209560067, gi... - gi\|209560067\|ref\|YP_002286539.1\| PTS system, lactose-specific IIA component (EIIA-Lac) (Lactose- per... gi\|94542775, gi\|... - gi\|94989267\|ref\|YP_597368.1\| PTS system, lactose-specific IIA component [Streptococcus pyogenes MGAS... gi\|94995127, gi\|... - gi\|94995127\|ref\|YP_603225.1\| PTS system, lactose-specific IIA component [Streptococcus pyogenes MGAS... gi\|139474414, gi... - gi\|139474414\|ref\|YP_001129130.1\| PTS system, lactose-specific IIA component [Streptococcus pyogenes ... gi\|71911447, gi\|... - gi\|71911447\|ref\|YP_282997.1\| PTS system, lactose-specific IIA component [Streptococcus pyogenes MGAS... gi\|56808782 - gi\|56808782\|ref\|ZP_00366498.1\| COG1447: Phosphotransferase system cellobiose-specific component IIA ... gi\|71803381, gi\|... - gi\|71904286\|ref\|YP_281089.1\| PTS system, lactose-specific IIA component [Streptococcus pyogenes MGAS... gi\|21905403, gi\|... - gi\|21911191\|ref\|NP_665459.1\| PTS system, lactose-specific IIA component [Streptococcus pyogenes MGAS... gi\|28811819, gi\|... - gi\|28896565\|ref\|NP_802915.1\| PTS system, lactose-specific IIA component [Streptococcus pyogenes SSI-... gi\|94544720, gi\|... - gi\|94991212\|ref\|YP_599312.1\| PTS system, lactose-specific IIA component [Streptococcus pyogenes MGAS... gi\|19749076, gi\|... - gi\|19749076\|gb\|AAL98472.1\| putative PTS system, lactose-specific component IIA [Streptococcus pyogen... gi\|94546664, gi\|... - gi\|94993156\|ref\|YP_601255.1\| PTS system, lactose-specific IIA component [Streptococcus pyogenes MGAS... gi\|50914989, gi\|... - gi\|50914989\|ref\|YP_060961.1\| PTS system, lactose-specific IIA component [Streptococcus pyogenes MGAS... gi\|15675727, gi\|... - gi\|15675727\|ref\|NP_269901.1\| PTS system, lactose-specific IIA component [Streptococcus pyogenes M1 G...	133.0	[0..1]	[102..1]
gi\|81429146, gi\|... - gi\|81429146\|ref\|YP_396147.1\| putative cellobiose-specific phosphotransferasesystem, enzyme IIA [Lact...	133.0	[0..1]	[103..1]
gi\|25011373, gi\|... - gi\|25011373\|ref\|NP_735768.1\| hypothetical protein gbs1331 [Streptococcus agalactiae NEM316], gi\|2441...	132.0	[0..1]	[102..1]
gi\|68446571, gi\|... - gi\|70725847\|ref\|YP_252761.1\| PTS system, lactose-specific IIA component [Staphylococcus haemolyticus... gi\|228271385, gi... - gi\|228474722\|ref\|ZP_04059453.1\| lactose-specific phosphotransferase enzyme iia component [Staphyloco...	131.0	[0..1]	[102..1]
PTLA_STRMU - Lactose-specific phosphotransferase enzyme IIA component OS=Streptococcus mutans GN=lacF PE=3 SV=1 PTLA_STRMU - Lactose-specific phosphotransferase enzyme IIA component OS=Streptococcus mutans serotype c (strain ...	131.0	[0..1]	[102..1]
PTLA_STAAM - Lactose-specific phosphotransferase enzyme IIA component OS=Staphylococcus aureus (strain Mu50 / ATC... PTLA_STAAN - Lactose-specific phosphotransferase enzyme IIA component OS=Staphylococcus aureus (strain N315) GN=l... gi\|151222307, gi... - gi\|151222307\|ref\|YP_001333129.1\| PTS system, lactose-specific IIA component [Staphylococcus aureus s... gi\|156722641, gi... - gi\|156980506\|ref\|YP_001442765.1\| PTS system, lactose-specific IIA component [Staphylococcus aureus s... gi\|255006974 - gi\|255006974\|ref\|ZP_05145575.2\| PTS system, lactose-specific IIA component [Staphylococcus aureus su... gi\|253727622, gi... - gi\|253734392\|ref\|ZP_04868557.1\| PTS system, lactose-specific IIA component [Staphylococcus aureus su... gi\|253726309, gi... - gi\|253729862\|ref\|ZP_04864027.1\| PTS system, lactose-specific IIA component [Staphylococcus aureus su... gi\|253316957 - gi\|253316957\|ref\|ZP_04840170.1\| PTS system, lactose-specific IIA component [Staphylococcus aureus su... gi\|251813374, gi... - gi\|251813374\|ref\|ZP_04827847.1\| PTS system, lactose-specific IIA component [Staphylococcus aureus su... gi\|227899032, gi... - gi\|227899032\|ref\|ZP_04016837.1\| PTS system, lactose-specific IIA component [Staphylococcus aureus su... gi\|227246648, gi... - gi\|227556972\|ref\|ZP_03987019.1\| PTS system, lactose-specific IIA component [Staphylococcus aureus su... gi\|149947153, gi... - gi\|90583775\|ref\|ZP_01239526.1\| Phosphotransferase system PTS, lactose/cellobiose-specific IIA subuni... gi\|148268636, gi... - gi\|90586487\|ref\|ZP_01242183.1\| Phosphotransferase system PTS, lactose/cellobiose-specific IIA subuni... gi\|160369207, gi... - gi\|161510398\|ref\|YP_001576057.1\| PTS system, lactose-specific IIA component [Staphylococcus aureus s... gi\|87160194\|ref\|... - PTS system, lactose-specific IIA component [Staphylococcus aureus subsp. aureus USA300], PTS system,... gi\|221139651 - gi\|221139651\|ref\|ZP_03564450.1\| PTS system, lactose-specific IIA component [Staphylococcus aureus su... gi\|221140521 - gi\|221140521\|ref\|ZP_03565014.1\| PTS system, lactose-specific IIA component [Staphylococcus aureus su... gi\|88196103, gi\|... - gi\|88196103\|ref\|YP_500918.1\| PTS system, lactose-specific IIA component [Staphylococcus aureus subsp... PTLA_STAAU - Lactose-specific phosphotransferase enzyme IIA component OS=Staphylococcus aureus GN=lacF PE=1 SV=1 PTLA_STAAC - Lactose-specific phosphotransferase enzyme IIA component OS=Staphylococcus aureus (strain COL) GN=la... PTLA_STAAW - Lactose-specific phosphotransferase enzyme IIA component OS=Staphylococcus aureus (strain MW2) GN=la... PTLA_STAAR - Lactose-specific phosphotransferase enzyme IIA component OS=Staphylococcus aureus (strain MRSA252) G... PTLA_STAAS - Lactose-specific phosphotransferase enzyme IIA component OS=Staphylococcus aureus (strain MSSA476) G... gi\|82657320, gi\|... - gi\|82751789\|ref\|YP_417530.1\| PTS system, lactose-specific IIA component [Staphylococcus aureus RF122... gi\|87160194, gi\|... - gi\|87160194\|ref\|YP_494787.1\| PTS system, lactose-specific IIA component [Staphylococcus aureus subsp... gi\|269203824\|ref... - PTS system, lactose-specific IIA component [Staphylococcus aureus subsp. aureus ED98]	131.0	[0..1]	[102..1]

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Predicted Domain #1

Region A:
Residues: [1-104]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNKEELELTT MEIVAYAGDA RSKYLEALNA ANGGDYDKAQ QLVLEGNDLI TEAHNVQTKM  60
   61 IQMEAQGKKI EVGFLVVHAQ DHLMTVMLLR DLVKNLINLY KKVN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	32.221849
Match:	1e2aA
Description:	Enzyme IIa from lactose specific PTS, IIa-lac
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein-N(PI)-phosphohistidine-sugar phosphotransferase activity	5.00429001244066	bayes_pls_golite062009
carbohydrate transmembrane transporter activity	4.03872487639957	bayes_pls_golite062009
transporter activity	1.32957030120524	bayes_pls_golite062009
transmembrane transporter activity	1.20211801626802	bayes_pls_golite062009
active transmembrane transporter activity	1.08511657750399	bayes_pls_golite062009
substrate-specific transporter activity	0.93495816074069	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.81702015470704	bayes_pls_golite062009
binding	0.569728786489819	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.34582307123923	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.0202700968382801	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: