YRC Public Data Repository - Protein Structure Prediction

Protein:	LUXS_VIBCH
Organism:	Vibrio cholerae
Length:	172 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LUXS_VIBCH.

Description	E-value	Query Range	Subject Range
LUXS_VIBPA - S-ribosylhomocysteine lyase OS=Vibrio parahaemolyticus GN=luxS PE=3 SV=1 LUXS_VIBPA - S-ribosylhomocysteine lyase OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) GN=luxS ... gi\|153838707, gi... - gi\|153838707\|ref\|ZP_01991374.1\| S-Ribosylhomocysteinase (LuxS) [Vibrio parahaemolyticus AQ3810], gi\|...	315.0	[0..1]	[171..1]
LUXS_VIBAL - S-ribosylhomocysteine lyase OS=Vibrio alginolyticus GN=luxS PE=3 SV=1	313.0	[0..1]	[171..1]
gi\|116183744, gi... - gi\|75854253\|ref\|ZP_00761958.1\| COG1854: LuxS protein involved in autoinducer AI2 synthesis [Vibrio s...	310.0	[0..1]	[171..1]
tr\|A0A085Q5F4\|A0... - S-ribosylhomocysteine lyase OS=Vibrio cholerae GN=luxS PE=3 SV=1, S-ribosylhomocysteine lyase OS=Vib... gi\|229350074, gi... - gi\|229512825\|ref\|ZP_04402292.1\| S-ribosylhomocysteine lyase/autoinducer-2 production protein LuxS [V... gi\|254292071, gi... - gi\|254292071\|ref\|ZP_04962847.1\| autoinducer-2 production protein [Vibrio cholerae AM-19226], gi\|1977... gi\|148873765, gi... - gi\|153830756\|ref\|ZP_01983423.1\| autoinducer-2 production protein [Vibrio cholerae 623-39], gi\|148873... gi\|75822528, gi\|... - gi\|75822528\|ref\|ZP_00752137.1\| COG1854: LuxS protein involved in autoinducer AI2 synthesis [Vibrio c...	310.0	[0..1]	[172..1]
gi\|91228769, gi\|... - gi\|91228769\|ref\|ZP_01262679.1\| S-ribosylhomocysteinase [Vibrio alginolyticus 12G01], gi\|91187676\|gb\|...	309.0	[0..1]	[171..1]
LUXS_VIBCB - S-ribosylhomocysteine lyase OS=Vibrio campbellii (strain ATCC BAA-1116 / BB120) GN=luxS PE=3 SV=3 LUXS_VIBHA - S-ribosylhomocysteine lyase - Vibrio harveyi	307.0	[0..1]	[171..1]
tr\|A0A085TI38\|A0... - S-ribosylhomocysteine lyase OS=Vibrio cholerae GN=luxS PE=3 SV=1 gi\|73611166 - gi\|73611166\|dbj\|BAE19929.1\| AI-2 synthase [Vibrio mimicus]	307.0	[0..1]	[172..1]
LUXS_ECOL5 - S-ribosylhomocysteine lyase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=luxS PE=3 SV=1 gi\|227834865, gi... - gi\|227888225\|ref\|ZP_04006030.1\| S-ribosylhomocysteine lyase [Escherichia coli 83972], gi\|227834865\|g... LUXS_ECOL6 - S-ribosylhomocysteine lyase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=luxS P... LUXS_ECOL6 - S-ribosylhomocysteine lyase OS=Escherichia coli O6 GN=luxS PE=3 SV=3 LUXS_ECOSM - S-ribosylhomocysteine lyase OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=luxS PE=3 SV=1 gi\|190908361, gi... - gi\|75241635\|ref\|ZP_00725472.1\| COG1854: LuxS protein involved in autoinducer AI2 synthesis [Escheric... LUXS_ECO81 - S-ribosylhomocysteine lyase OS=Escherichia coli O81 (strain ED1a) GN=luxS PE=3 SV=1	307.0	[0..1]	[171..1]
LUXS_VIBVU - S-ribosylhomocysteine lyase OS=Vibrio vulnificus (strain CMCP6) GN=luxS PE=3 SV=1 LUXS_VIBVU - S-ribosylhomocysteine lyase OS=Vibrio vulnificus GN=luxS PE=3 SV=1 LUXS_VIBVY - S-ribosylhomocysteine lyase OS=Vibrio vulnificus (strain YJ016) GN=luxS PE=3 SV=1	307.0	[0..1]	[171..1]
gi\|90323999, gi\|... - gi\|90414885\|ref\|ZP_01222850.1\| S-ribosylhomocysteinase [Photobacterium profundum 3TCK], gi\|90323999\|...	306.0	[0..1]	[171..1]

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Predicted Domain #1

Region A:
Residues: [1-172]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLLDSFTVD HTRMNAPAVR VAKTMQTPKG DTITVFDLRF TMPNKDILSE RGIHTLEHLY  60
   61 AGFMRNHLNG SQVEIIDISP MGCRTGFYMS LIGAPTEQQV AQAWLAAMQD VLKVESQEQI 120
  121 PELNEYQCGT AAMHSLEEAK AIAKNVIAAG ISVNRNDELA LPESMLNELK VH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	79.30103
Match:	1j6wA
Description:	Autoinducer-2 production protein LuxS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
S-ribosylhomocysteine lyase activity	1.74759627448878	bayes_pls_golite062009
quorum sensing signal generator activity	1.39649645139585	bayes_pls_golite062009
quorum sensing response regulator activity	1.39649645139585	bayes_pls_golite062009
catalytic activity	0.00996887145100289	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: