YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|7431780
Organism:	Synechocystis sp.
Length:	1556 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7431780.

Description	E-value	Query Range	Subject Range
gi\|1122381 - gi\|1122381\|emb\|CAA63218.1\| ferredoxin-glutamate synthase [Synechocystis sp. PCC 6803]	1824.0	[0..1]	[1556..1]
gi\|33357689, gi\|... - gi\|33357689\|pdb\|1OFE\|A Chain A, Glutamate Synthase From Synechocystis Sp In Complex With 2- Oxogluta... gi\|33357689, gi\|... - gi\|33357690\|pdb\|1OFE\|B Chain B, Glutamate Synthase From Synechocystis Sp In Complex With 2- Oxogluta...	1810.0	[0..37]	[1556..1]
gi\|23125133, gi\|... - gi\|23125133\|ref\|ZP_00107080.1\| COG0069: Glutamate synthase domain 2 [Nostoc punctiforme PCC 73102], ...	1797.0	[0..9]	[1545..4]
gi\|1369908 - gi\|1369908\|dbj\|BAA12858.1\| ferredoxin-dependent glutamate synthase [Leptolyngbya boryana] gi\|1369908\|dbj\|B... - ferredoxin-dependent glutamate synthase [Leptolyngbya boryana]	1795.0	[0..10]	[1551..7]
gi\|67857089, gi\|... - gi\|67920972\|ref\|ZP_00514491.1\| Glutamate synthase (NADPH) [Crocosphaera watsonii WH 8501], gi\|678570...	1794.0	[0..4]	[1554..2]
gi\|17133480, gi\|... - gi\|17231836\|ref\|NP_488384.1\| ferredoxin-glutamate synthase [Nostoc sp. PCC 7120], gi\|17133480\|dbj\|BA... gi\|25284769 - pir\|\|AI2348 ferredoxin-glutamate synthase [imported] - Nostoc sp. (strain PCC 7120)	1780.0	[0..10]	[1546..8]
gi\|75907517, gi\|... - gi\|75907517\|ref\|YP_321813.1\| glutamate synthase (ferredoxin) [Anabaena variabilis ATCC 29413], gi\|75...	1779.0	[0..10]	[1546..8]
gi\|81168580, gi\|... - gi\|81299699\|ref\|YP_399907.1\| glutamate synthase (ferredoxin) [Synechococcus elongatus PCC 7942], gi\|...	1777.0	[0..11]	[1556..1]
gi\|56750659, gi\|... - gi\|56750659\|ref\|YP_171360.1\| ferredoxin-dependent glutamate synthase [Synechococcus elongatus PCC 63...	1774.0	[0..11]	[1556..1]

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Predicted Domain #1

Region A:
Residues: [1-1556]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFQYPLLAP MTNSSVATNS NQPFLGQPWL VEERDACGVG FIANLRGKPD HTLVEQALKA  60
   61 LGCMEHRGGC SADNDSGDGA GVMTAIPREL LAQWFNTRNL PMPDGDRLGV GMVFLPQEPS 120
  121 AREVARAYVE EVVRLEKLTV LGWREVPVNS DVLGIQAKNN QPHIEQILVT CPEGCAGDEL 180
  181 DRRLYIARSI IGKKLAEDFY VCSFSCRTIV YKGMVRSIIL GEFYLDLKNP GYTSNFAVYH 240
  241 RRFSTNTMPK WPLAQPMRLL GHNGEINTLL GNINWMAARE KELEVSGWTK AELEALTPIV 300
  301 NQANSDSYNL DSALELLVRT GRSPLEAAMI LVPEAYKNQP ALKDYPEISD FHDYYSGLQE 360
  361 PWDGPALLVF SDGKIVGAGL DRNGLRPARY CITKDDYIVL GSEAGVVDLP EVDIVEKGRL 420
  421 APGQMIAVDL AEQKILKNYQ IKQQAAQKYP YGEWIKIQRQ TVASDSFAEK TLFNDAQTVL 480
  481 QQQAAFGYTA EDVEMVVVPM ASQGKEPTFC MGDDTPLAVL SHKPRLLYDY FKQRFAQVTN 540
  541 PPIDPLRENL VMSLAMFLGK RGNLLEPKAE SARTIKLRSP LVNEVELQAI KTGQLQVAEV 600
  601 STLYDLDGVN SLETALDNLV KTAIATVQAG AEILVLTDRP NGAILTENQS FIPPLLAVGA 660
  661 VHHHLIRAGL RLKASLIVDT AQCWSTHHFA CLVGYGASAI CPYLALESVR QWWLDEKTQK 720
  721 LMENGRLDRI DLPTALKNYR QSVEAGLFKI LSKMGISLLA SYHGAQIFEA IGLGAELVEY 780
  781 AFAGTTSRVG GLTIADVAGE VMVFHGMAFP EMAKKLENFG FVNYRPGGEY HMNSPEMSKS 840
  841 LHKAVAAYKV GGNGNNGEAY DHYELYRQYL KDRPVTALRD LLDFNADQPA ISLEEVESVE 900
  901 SIVKRFCTGG MSLGALSREA HETLAIAMNR LGAKSNSGEG GEDVVRYLTL DDVDSEGNSP 960
  961 TLPHLHGLQN GDTANSAIKQ IASGRFGVTP EYLMSGKQLE IKMAQGAKPG EGGQLPGKKV1020
 1021 SEYIAMLRRS KPGVTLISPP PHHDIYSIED LAQLIYDLHQ INPEAQVSVK LVAEIGIGTI1080
 1081 AAGVAKANAD IIQISGHDGG TGASPLSSIK HAGSPWELGV TEVHRVLMEN QLRDRVLLRA1140
 1141 DGGLKTGWDV VMAALMGAEE YGFGSIAMIA EGCIMARVCH TNNCPVGVAT QQERLRQRFK1200
 1201 GVPGQVVNFF YFIAEEVRSL LAHLGYRSLD DIIGRTDLLK VRSDVQLSKT QNLTLDCLLN1260
 1261 LPDTKQNRQW LNHEPVHSNG PVLDDDILAD PDIQEAINHQ TTATKTYRLV NTDRTVGTRL1320
 1321 SGAIAKKYGN NGFEGNITLN FQGAAGQSFG AFNLDGMTLH LQGEANDYVG KGMNGGEIVI1380
 1381 VPHPQASFAP EDNVIIGNTC LYGATGGNLY ANGRAGERFA VRNSVGKAVI EGAGDHCCEY1440
 1441 MTGGVIVVLG PVGRNVGAGM TGGLAYFLDE VGDLPEKINP EIITLQRITA SKGEEQLKSL1500
 1501 ITAHVEHTGS PKGKAILANW SDYLGKFWQA VPPSEKDSPE ANGDVSLTGE KTLTSV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	1llwA
Description:	Alpha subunit of glutamate synthase, C-terminal domain; Alpha subunit of glutamate synthase, central and FMN domains; Alpha subunit of glutamate synthase, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
glutamate synthase activity	10.2123323896554	bayes_pls_golite062009
glutamate synthase activity, NADH or NADPH as acceptor	9.64220719720108	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor	8.40816887743017	bayes_pls_golite062009
glutamate synthase (NADPH) activity	7.71666213946687	bayes_pls_golite062009
oxidoreductase activity	2.15666801512485	bayes_pls_golite062009
catalytic activity	1.94749091175302	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors	0.330721070169443	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: