YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|7429908
Organism:	Synechocystis sp.
Length:	1252 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7429908.

Description	E-value	Query Range	Subject Range
gi\|21229014, gi\|... - gi\|21229014\|ref\|NP_634936.1\| 5-oxoprolinase [Methanosarcina mazei Go1], gi\|20907558\|gb\|AAM32608.1\| 5...	1553.0	[0..2]	[1252..7]
gi\|19916241, gi\|... - gi\|20091138\|ref\|NP_617213.1\| 5-oxoprolinase (ATP-hydrolyzing) [Methanosarcina acetivorans C2A], gi\|1...	1551.0	[0..2]	[1250..7]
gi\|73670788, gi\|... - gi\|73670788\|ref\|YP_306803.1\| 5-oxoprolinase (ATP-hydrolyzing) [Methanosarcina barkeri str. Fusaro], ...	1535.0	[0..2]	[1252..7]
gi\|68186565, gi\|... - gi\|91774100\|ref\|YP_566792.1\| 5-oxoprolinase (ATP-hydrolyzing) [Methanococcoides burtonii DSM 6242], ...	1484.0	[0..2]	[1230..7]
gi\|84358800, gi\|... - gi\|84358800\|ref\|ZP_00983568.1\| COG0145: N-methylhydantoinase A/acetone carboxylase, beta subunit [Bu...	1481.0	[0..2]	[1252..16]
OPLA_ARATH - 5-oxoprolinase OS=Arabidopsis thaliana GN=OXP1 PE=2 SV=1	1460.0	[0..2]	[1250..9]
gi\|33592938, gi\|... - gi\|33592938\|ref\|NP_880582.1\| 5-oxoprolinase [Bordetella pertussis Tohama I], gi\|33572586\|emb\|CAE4217...	1460.0	[0..2]	[1249..3]
gi\|215767648, gi... - gi\|34905886\|ref\|NP_914290.1\| similar to 5-oxoprolinase [Oryza sativa (japonica cultivar-group)], gi\|...	1452.0	[0..3]	[1251..8]
gi\|91692735, gi\|... - gi\|91780075\|ref\|YP_555282.1\| 5-oxoprolinase (ATP-hydrolyzing) [Burkholderia xenovorans LB400], gi\|91...	1451.0	[0..2]	[1252..19]
gi\|25305516 - pir\|\|AI3584 N-methylhydantoinase (ATP-hydrolysing) (EC 3.5.2.14) [imported] - Brucella melitensis (s... gi\|17984780, gi\|... - gi\|17988947\|ref\|NP_541580.1\| N-methylhydantoinase (ATP-hydrolyzing) / 5-oxoprolinase [Brucella melit...	1450.0	[0..2]	[1252..10]

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Predicted Domain #1

Region A:
Residues: [1-76]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKFFVDRGG TFTDIVAITK DTKLAQHSAK DRRFSVFILP TKETVILFKL LSENPELYDD  60
   61 AVIHGIRIIL GLSSNE

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	0.997
Match:	2dpnA
Description:	No description for 2dpnA was found.

Predicted Domain #2

Region A:
Residues: [77-670]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PIAPEKVSMV KMGTTVATNA LLEQKGDPLV LVMTQGFRDG LAIAYQNRPD IFALEIKKPS  60
   61 LLYGPVIEAM ERINAQGEIL QPLDKHRIHQ DLQQAYDQGI RSVAIALMHS YLYPDHELII 120
  121 TEIAQNIGFT QISRSSEVSP LIKYIYRGDT TVVDAYLSPL LRRYVDQVQG QLPGITVQFM 180
  181 QSHGGLVDGS HFQGRDSILS GPAGGIVGAV KTSQRAGFRN IITFDMGGTS TDVAHFNGTY 240
  241 ERLWETEIAG VRLRVPSLAI HTVAAGGGSI LHFDGQRYQV GPDSAGANPG PACYRRGGPL 300
  301 TVTDANVMVG RVQKSYFPPV FGPEGNQPLD IDIVQEKFID LANQIAQFTA IKPIPEEVAD 360
  361 GFLAIAVENM ANAIKKISLQ RGYDLESYTL CCFGGAGGQL VCRLADRLGI SKIFLHPYSG 420
  421 VLSAYGMGLA EQRALRAMTI EQPLTADNLE SLLSNYQTLE TQLAETFVNS SNSNGKAENF 480
  481 SKSPEIRRQI DLKYRGTDTS LSLDFCPDLT SLITQFTEQH QQRYGFNQTG TPLTIAAISL 540
  541 EYIQPLDLPP EPCLASVVKP AQALEMVDFY GDRQWHAMPV YQRQQLAPHQ VITG

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.29
Match:	1yuwA
Description:	crystal structure of bovine hsc70(aa1-554)E213A/D214A mutant
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
carbohydrate kinase activity	1.59015355865021	bayes_pls_golite062009
kinase activity	0.936112985314189	bayes_pls_golite062009
binding	0.874703945174078	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.839311348589465	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.644753323874683	bayes_pls_golite062009
hexokinase activity	0.570508441475985	bayes_pls_golite062009
hydrolase activity	0.440062766964367	bayes_pls_golite062009
catalytic activity	0.308539563780047	bayes_pls_golite062009
transferase activity	0.0223144423385645	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [671-743]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PAMIAEETGT IVVDLGWQAQ LGQASPWEPQ PCHLVLEKIV NQTKAAPDSI NNKEELEVKV  60
   61 NTDSYETISG NQV

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [744-840]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPVRLEIFKN LYQFIAEEMG IVLQNTASSV NIKERLDFSC AIFDANGDLV ANAPHIPVHL  60
   61 GSMGESVKAL LHDRHQQLQP GDVYLSNNPY NGGTHLP

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5

Region A:
Residues: [841-949]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DVTVITPLFD SAGKEILFYV ASRGHQADLG GITPGSMPPH SQNINQEGIL FDNELLVKAG  60
   61 ELQTQAIRNH LLNNIYPARN PEQNLADFSA QIAANQRGIM GLESMVAQY

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6

Region A:
Residues: [950-1092]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLNTVQQYMA HVQNNAEQAV TKAIAKLKSG QFVTEMDNGI RIAVTITVNA SQGTAIIDFS  60
   61 GTSPQGDHNF NTPKAVVQAV VLYVFRTLVQ DPIPLNAGCL KPLKIIIPPG CLLDPQYPAA 120
  121 VVAGNVETSQ AIADTLYGAL GCL

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7

Region A:
Residues: [1093-1149]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AASQGTMNNL TFGDGQYQYY ETIAGGSGAG PSFAGCDAVQ THMTNSRLTD PEILESR

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8

Region A:
Residues: [1150-1252]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FPVLLEQFAI RPHSGGAGKF PGGNGIVRQF KFLQPLSVAI LANRRRVAPF GLAGGEAGAV  60
   61 GENWLLRRSG DKVRLDSCAQ VDVAPGDRLI IKTPGGGGYG HRD

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: