YRC Public Data Repository - Protein Structure Prediction

Protein:	KTHY_CAUCR
Organism:	Caulobacter crescentus CB15
Length:	208 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KTHY_CAUCR.

Description	E-value	Query Range	Subject Range
gi\|84326490 - gi\|84326490\|ref\|ZP_00974517.1\| COG0125: Thymidylate kinase [Pseudomonas aeruginosa 2192]	198.0	[0..2]	[207..1]
gi\|71916914, gi\|... - gi\|72163182\|ref\|YP_290839.1\| thymidylate kinase [Thermobifida fusca YX], gi\|71916914\|gb\|AAZ56816.1\| ...	193.0	[0..4]	[206..465]
gi\|113733700, gi... - gi\|113933479\|ref\|ZP_01419381.1\| Thymidylate kinase [Caulobacter sp. K31], gi\|113733700\|gb\|EAU14768.1...	192.0	[0..2]	[208..5]
gi\|88778555, gi\|... - gi\|88798792\|ref\|ZP_01114375.1\| Thymidylate kinase [Reinekea sp. MED297], gi\|88778555\|gb\|EAR09747.1\| ...	192.0	[0..2]	[205..1]
KTHY_BRAJA - Thymidylate kinase OS=Bradyrhizobium japonicum GN=tmk PE=3 SV=1 KTHY_BRADU - Thymidylate kinase OS=Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USD...	191.0	[0..3]	[206..12]
gi\|62424658 - gi\|62424658\|ref\|ZP_00379801.1\| COG0477: Permeases of the major facilitator superfamily [Brevibacteri...	191.0	[0..4]	[206..426]
gi\|89352271, gi\|... - gi\|89358094\|ref\|ZP_01195916.1\| Thymidylate kinase [Xanthobacter autotrophicus Py2], gi\|89352271\|gb\|E...	190.0	[0..1]	[208..1]
gi\|113904572, gi... - gi\|145596534\|ref\|YP_001160831.1\| thymidylate kinase [Salinispora tropica CNB-440], gi\|145305871\|gb\|A...	190.0	[0..4]	[207..448]
gi\|66782947, gi\|... - gi\|94986082\|ref\|YP_605446.1\| thymidylate kinase [Deinococcus geothermalis DSM 11300], gi\|94556363\|gb...	190.0	[0..1]	[206..1]
gi\|81298904, gi\|... - gi\|81298904\|ref\|YP_399112.1\| thymidylate kinase [Synechococcus elongatus PCC 7942], gi\|81167785\|gb\|A...	189.0	[0..1]	[205..1]

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Predicted Domain #1

Region A:
Residues: [1-208]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTQGFFISFE GGEGAGKSTQ IRRLADRLKA AGHDVIVTRE PGGSPGAEAI RELLVNGAAD  60
   61 RWSPVTESLL MYAARRDHIE RVIRPGLARG AVVLCDRFAD STRAYQGAGG DAPASLIAAL 120
  121 EEHVLGGTVP VLTLILDLPA EVGLQRAEAR GGAARFESKG LAFHERLRAG YLEIARREPD 180
  181 RCVVIDADAE LDAVTAAISD VVVQRLGL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	42.69897
Match:	4tmkA
Description:	Thymidylate kinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nucleobase, nucleoside, nucleotide kinase activity	3.31021342806183	bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism	3.01286198424677	bayes_pls_golite062009
nucleotide kinase activity	2.24094813695083	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	2.06460241490722	bayes_pls_golite062009
substrate-specific transporter activity	2.0114051513686	bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor	1.96697952975573	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.92626167278464	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	1.9136419736217	bayes_pls_golite062009
ion transmembrane transporter activity	1.6854386921174	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	1.64467072658718	bayes_pls_golite062009
kinase activity	1.60827037072506	bayes_pls_golite062009
cation transmembrane transporter activity	1.5008821138859	bayes_pls_golite062009
binding	1.25659194713805	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
nucleotide binding	0.828524126097217	bayes_pls_golite062009
purine ribonucleotide binding	0.810407092593521	bayes_pls_golite062009
ribonucleotide binding	0.810379637652019	bayes_pls_golite062009
purine nucleotide binding	0.805605269661092	bayes_pls_golite062009
hydrolase activity	0.420858111948277	bayes_pls_golite062009
adenylate kinase activity	0.373057703057608	bayes_pls_golite062009
nucleic acid binding	0.216266069700019	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: