YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|25293702
Organism:	Streptococcus pneumoniae
Length:	329 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|25293702.

Description	E-value	Query Range	Subject Range
gi\|221313187 - gi\|221313187\|ref\|ZP_03594992.1\| hypothetical protein BsubsN3_05622 [Bacillus subtilis subsp. subtili... LPLJ_BACSU - Lipoate-protein ligase LplJ OS=Bacillus subtilis (strain 168) GN=lplJ PE=1 SV=1 gi\|221322385 - gi\|221322385\|ref\|ZP_03603679.1\| hypothetical protein BsubsS_05677 [Bacillus subtilis subsp. subtilis... gi\|221318110 - gi\|221318110\|ref\|ZP_03599404.1\| hypothetical protein BsubsJ_05571 [Bacillus subtilis subsp. subtilis... LPLJ_BACSU, LPLA... - Lipoate-protein ligase LplJ OS=Bacillus subtilis GN=lplJ PE=1 SV=1, Putative lipoate-protein ligase ...	387.0	[0..1]	[328..1]
gi\|168483222, gi... - gi\|172043498\|gb\|EDT51544.1\| lipoate protein ligase A [Streptococcus pneumoniae CDC1873-00], gi\|16848... gi\|25293705 - pir\|\|G98002 lipoate protein ligase A (EC 6.-.-.-) [imported] - Streptococcus pneumoniae (strain R6) gi\|15458668, gi\|... - gi\|15903091\|ref\|NP_358641.1\| lipoate-protein ligase, putative [Streptococcus pneumoniae R6], gi\|1545... gi\|116077327, gi... - gi\|116516751\|ref\|YP_816498.1\| lipoate-protein ligase, putative [Streptococcus pneumoniae D39], gi\|11... gi\|148985768, gi... - gi\|148985768\|ref\|ZP_01818896.1\| lipoate-protein ligase, putative [Streptococcus pneumoniae SP3-BS71]... gi\|225725441, gi... - gi\|225856837\|ref\|YP_002738348.1\| lipoate protein ligase A [Streptococcus pneumoniae P1031], gi\|22572...	386.0	[0..1]	[329..1]
gi\|56963378, gi\|... - gi\|56963378\|ref\|YP_175109.1\| lipoate-protein ligase [Bacillus clausii KSM-K16], gi\|56909621\|dbj\|BAD6...	382.0	[0..1]	[328..1]
gi\|228656885, gi... - gi\|229126496\|ref\|ZP_04255510.1\| Lipoyltransferase and lipoate-protein ligase [Bacillus cereus BDRD-C... gi\|229108652, gi... - gi\|229108652\|ref\|ZP_04238263.1\| Lipoyltransferase and lipoate-protein ligase [Bacillus cereus Rock1-... gi\|228957464, gi... - gi\|228957464\|ref\|ZP_04119218.1\| Lipoyltransferase and lipoate-protein ligase [Bacillus thuringiensis... gi\|29894784, gi\|... - gi\|30019241\|ref\|NP_830872.1\| lipoate-protein ligase A [Bacillus cereus ATCC 14579], gi\|29894784\|gb\|A...	381.0	[0..1]	[328..1]
gi\|25293701 - pir\|\|C83735 lipoate-protein ligase lplA [imported] - Bacillus halodurans (strain C-125) gi\|10173297, gi\|... - gi\|15613246\|ref\|NP_241549.1\| lipoate-protein ligase [Bacillus halodurans C-125], gi\|10173297\|dbj\|BAB...	380.0	[0..1]	[328..1]
gi\|228693220, gi... - gi\|229090143\|ref\|ZP_04221393.1\| Lipoyltransferase and lipoate-protein ligase [Bacillus cereus Rock3-... gi\|51977692, gi\|... - gi\|52144223\|ref\|YP_082605.1\| lipoate-protein ligase A [Bacillus cereus E33L], gi\|51977692\|gb\|AAU1924... gi\|217958670, gi... - gi\|217958670\|ref\|YP_002337218.1\| putative lipoate-protein ligase A [Bacillus cereus AH187], gi\|21706... gi\|206745219, gi... - gi\|206976536\|ref\|ZP_03237442.1\| putative lipoate-protein ligase A [Bacillus cereus H3081.97], gi\|206... gi\|228588099, gi... - gi\|229195400\|ref\|ZP_04322169.1\| Lipoyltransferase and lipoate-protein ligase [Bacillus cereus m1293]... gi\|196037699, gi... - gi\|196037699\|ref\|ZP_03105010.1\| putative lipoate-protein ligase A [Bacillus cereus NVH0597-99], gi\|1... gi\|228645535, gi... - gi\|229137878\|ref\|ZP_04266477.1\| Lipoyltransferase and lipoate-protein ligase [Bacillus cereus BDRD-S...	380.0	[0..1]	[328..1]
gi\|218539929, gi... - gi\|218902285\|ref\|YP_002450119.1\| putative lipoate-protein ligase A [Bacillus cereus AH820], gi\|21853... gi\|227816061, gi... - gi\|227816061\|ref\|YP_002816070.1\| putative lipoate-protein ligase A [Bacillus anthracis str. CDC 684]... gi\|167529210, gi... - gi\|167635382\|ref\|ZP_02393696.1\| putative lipoate-protein ligase A [Bacillus anthracis str. A0442], g... gi\|228926239, gi... - gi\|228926239\|ref\|ZP_04089314.1\| Lipoyltransferase and lipoate-protein ligase [Bacillus thuringiensis... gi\|165871825, gi... - gi\|165871825\|ref\|ZP_02216468.1\| putative lipoate-protein ligase A [Bacillus anthracis str. A0488], g... gi\|229120713, gi... - gi\|229120713\|ref\|ZP_04249956.1\| Lipoyltransferase and lipoate-protein ligase [Bacillus cereus 95/820... gi\|170688096, gi... - gi\|170688096\|ref\|ZP_02879308.1\| putative lipoate-protein ligase A [Bacillus anthracis str. A0465], g... gi\|229267042, gi... - gi\|229602634\|ref\|YP_002865632.1\| putative lipoate-protein ligase A [Bacillus anthracis str. A0248], ... gi\|49477084, gi\|... - gi\|49477084\|ref\|YP_035340.1\| lipoate-protein ligase A [Bacillus thuringiensis serovar konkukian str.... gi\|167640201, gi... - gi\|167640201\|ref\|ZP_02398467.1\| putative lipoate-protein ligase A [Bacillus anthracis str. A0193], g... gi\|254682735 - gi\|254682735\|ref\|ZP_05146596.1\| putative lipoate-protein ligase A [Bacillus anthracis str. CNEVA-906... gi\|172080919, gi... - gi\|177654212\|ref\|ZP_02936185.1\| putative lipoate-protein ligase A [Bacillus anthracis str. A0174], g... gi\|254725526 - gi\|254725526\|ref\|ZP_05187308.1\| putative lipoate-protein ligase A [Bacillus anthracis str. A1055] gi\|170707620, gi... - gi\|170707620\|ref\|ZP_02898072.1\| putative lipoate-protein ligase A [Bacillus anthracis str. A0389], g... gi\|254734152 - gi\|254734152\|ref\|ZP_05191865.1\| putative lipoate-protein ligase A [Bacillus anthracis str. Western N... gi\|195990934, gi... - gi\|196036460\|ref\|ZP_03103856.1\| putative lipoate-protein ligase A [Bacillus cereus W], gi\|195990934\|... gi\|254740204 - gi\|254740204\|ref\|ZP_05197896.1\| putative lipoate-protein ligase A [Bacillus anthracis str. Kruger B] gi\|190562105, gi... - gi\|190566553\|ref\|ZP_03019470.1\| putative lipoate-protein ligase A [Bacillus anthracis Tsiankovskii-I... gi\|254753543 - gi\|254753543\|ref\|ZP_05205579.1\| putative lipoate-protein ligase A [Bacillus anthracis str. Vollum] gi\|254758641 - gi\|254758641\|ref\|ZP_05210668.1\| putative lipoate-protein ligase A [Bacillus anthracis str. Australia... gi\|49177965, gi\|... - gi\|49184038\|ref\|YP_027290.1\| lipoate-protein ligase A, putative [Bacillus anthracis str. Sterne], gi... gi\|47526363, gi\|... - gi\|47526363\|ref\|YP_017712.1\| lipoate-protein ligase A, putative [Bacillus anthracis str. 'Ames Ances... gi\|30261205, gi\|... - gi\|30261205\|ref\|NP_843582.1\| lipoate-protein ligase A, putative [Bacillus anthracis str. Ames], gi\|3... gi\|21399015, gi\|... - gi\|65318471\|ref\|ZP_00391430.1\| COG0095: Lipoate-protein ligase A [Bacillus anthracis str. A2012], re...	380.0	[0..1]	[328..1]
gi\|42736183, gi\|... - gi\|42780264\|ref\|NP_977511.1\| lipoate-protein ligase A, putative [Bacillus cereus ATCC 10987], gi\|427...	380.0	[0..1]	[328..1]
gi\|152023404, gi... - gi\|89201729\|ref\|ZP_01180465.1\| Lipoyltransferase and lipoate-protein ligase [Bacillus cereus subsp. ...	380.0	[0..1]	[328..1]
gi\|218545470, gi... - gi\|218896140\|ref\|YP_002444551.1\| putative lipoate-protein ligase A [Bacillus cereus G9842], gi\|21854... gi\|228904013, gi... - gi\|228904013\|ref\|ZP_04068119.1\| Lipoyltransferase and lipoate-protein ligase [Bacillus thuringiensis... gi\|74493138, gi\|... - gi\|75759371\|ref\|ZP_00739467.1\| Lipoate-protein ligase A [Bacillus thuringiensis serovar israelensis ... gi\|228795496, gi... - gi\|228964146\|ref\|ZP_04125269.1\| Lipoyltransferase and lipoate-protein ligase [Bacillus thuringiensis...	380.0	[0..1]	[328..1]

Back

Predicted Domain #1

Region A:
Residues: [1-329]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKYIINHSND TAFNIALEEY AFKHLLDEDQ IFLLWINKPS IIVGRHQNTI EEINRDYVRE  60
   61 NGIEVVRRIS GGGAVYHDLN NLNYTIISKE DENKAFDFKS FSTPVINTLA QLGVKAEFTG 120
  121 RNDLEIDGKK FCGNAQAYIN GRIMHHGCLL FDVDLSVLAN ALKVSKDKFE SKGVKSVRAR 180
  181 VTNIINELPK KITVEKFRDL LLEYMKKEYP EMTEYVFSEE ELAEINRIKD TKFGTWDWNY 240
  241 GKSPEFNVRR GIKFTSGKVE VFANVTESKI QDIKIYGDFF GIEDVAAVED VLRGVKYERE 300
  301 DVLKALKTID ITRYFAGISR EEIAEAVVG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	108.0
Match:	1vqzA
Description:	Crystal structure of putative Lipoate-protein ligase (np_345629.1) from Streptococcus pneumoniae tigr4 at 1.99 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ligase activity, forming carbon-oxygen bonds	3.33073922220594	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	3.33073922220594	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	3.33034630936933	bayes_pls_golite062009
ligase activity	3.05852492533937	bayes_pls_golite062009
catalytic activity	2.36416267096403	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: