YRC Public Data Repository - Protein Structure Prediction

Protein:	AHPD_STRAW
Organism:	Streptomyces avermitilis MA-4680
Length:	177 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AHPD_STRAW.

Description	E-value	Query Range	Subject Range
AHPD_STRCO - Alkyl hydroperoxide reductase AhpD OS=Streptomyces coelicolor GN=ahpD PE=3 SV=1 AHPD_STRCO - Alkyl hydroperoxide reductase AhpD OS=Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) G...	188.0	[0..1]	[176..1]
AHPD_CORDI - Alkyl hydroperoxide reductase AhpD OS=Corynebacterium diphtheriae GN=ahpD PE=3 SV=1 AHPD_CORDI - Alkyl hydroperoxide reductase AhpD OS=Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 /...	174.0	[0..1]	[173..1]
AHPD_BRUSI - Alkyl hydroperoxide reductase AhpD OS=Brucella suis (strain ATCC 23445 / NCTC 10510) GN=ahpD PE=3 SV... gi\|254699929 - gi\|254699929\|ref\|ZP_05161757.1\| alkylhydroperoxidase [Brucella suis bv. 5 str. 513] gi\|254705808 - gi\|254705808\|ref\|ZP_05167636.1\| alkylhydroperoxidase [Brucella pinnipedialis M163/99/10] AHPD_BRUME - Alkyl hydroperoxide reductase ahpD OS=Brucella melitensis GN=ahpD PE=3 SV=1 AHPD_BRUME - Alkyl hydroperoxide reductase AhpD OS=Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC ... gi\|254715573 - gi\|254715573\|ref\|ZP_05177384.1\| alkylhydroperoxidase [Brucella ceti M13/05/1] gi\|254711037 - gi\|254711037\|ref\|ZP_05172848.1\| alkylhydroperoxidase [Brucella pinnipedialis B2/94] gi\|254712500 - gi\|254712500\|ref\|ZP_05174311.1\| alkylhydroperoxidase [Brucella ceti M644/93/1]	170.0	[0..1]	[172..1]
AHPD_BRUAB - Alkyl hydroperoxide reductase AhpD OS=Brucella abortus biovar 1 (strain 9-941) GN=ahpD PE=3 SV=1 AHPD_BRUA2 - Alkyl hydroperoxide reductase AhpD OS=Brucella abortus (strain 2308) GN=ahpD PE=3 SV=1 AHPD_BRUAB - Alkyl hydroperoxide reductase ahpD OS=Brucella abortus GN=ahpD PE=3 SV=1 AHPD_BRUA1 - Alkyl hydroperoxide reductase AhpD OS=Brucella abortus (strain S19) GN=ahpD PE=3 SV=1 gi\|254698730 - gi\|254698730\|ref\|ZP_05160558.1\| Alkylhydroperoxidase AhpD [Brucella abortus bv. 2 str. 86/8/59] gi\|254732175 - gi\|254732175\|ref\|ZP_05190753.1\| Alkylhydroperoxidase AhpD [Brucella abortus bv. 4 str. 292] gi\|254690947 - gi\|254690947\|ref\|ZP_05154201.1\| Alkylhydroperoxidase AhpD [Brucella abortus bv. 6 str. 870] gi\|254695744 - gi\|254695744\|ref\|ZP_05157572.1\| Alkylhydroperoxidase AhpD [Brucella abortus bv. 3 str. Tulya]	169.0	[0..1]	[172..1]
AHPD_BRUSU - Alkyl hydroperoxide reductase ahpD OS=Brucella suis GN=ahpD PE=3 SV=1 AHPD_BRUC2 - Alkyl hydroperoxide reductase AhpD OS=Brucella canis (strain ATCC 23365 / NCTC 10854) GN=ahpD PE=3 S... gi\|254703051 - gi\|254703051\|ref\|ZP_05164879.1\| alkylhydroperoxidase [Brucella suis bv. 3 str. 686] AHPD_BRUSU - Alkyl hydroperoxide reductase AhpD OS=Brucella suis biovar 1 (strain 1330) GN=ahpD PE=3 SV=1	169.0	[0..1]	[172..1]
AHPD_MYCPA - Alkyl hydroperoxide reductase AhpD OS=Mycobacterium paratuberculosis GN=ahpD PE=3 SV=1 gi\|254775316 - gi\|254775316\|ref\|ZP_05216832.1\| AhpD [Mycobacterium avium subsp. avium ATCC 25291] AHPD_MYCPA - Alkyl hydroperoxide reductase AhpD OS=Mycobacterium paratuberculosis (strain ATCC BAA-968 / K-10) GN...	168.0	[0..1]	[176..1]
gi\|84702543, gi\|... - gi\|84702543\|ref\|ZP_01017118.1\| AhpD, alkyl hydroperoxide reductase D [Parvularcula bermudensis HTCC2...	167.0	[0..1]	[175..1]
AHPD_COXBN - Alkyl hydroperoxide reductase AhpD OS=Coxiella burnetii (strain Dugway 5J108-111) GN=ahpD PE=3 SV=3 gi\|94490865, gi\|... - gi\|94490865\|ref\|ZP_01298091.1\| hypothetical protein CburD_01002043 [Coxiella burnetii Dugway 7E9-12]... AHPD_COXBR - Alkyl hydroperoxide reductase AhpD OS=Coxiella burnetii (strain RSA 331 / Henzerling II) GN=ahpD PE=... AHPD_COXB2 - Alkyl hydroperoxide reductase AhpD OS=Coxiella burnetii (strain CbuG_Q212) GN=ahpD PE=3 SV=1 AHPD_COXBU - Alkyl hydroperoxide reductase AhpD OS=Coxiella burnetii (strain RSA 493 / Nine Mile phase I) GN=ahpD... AHPD_COXBU - Alkyl hydroperoxide reductase AhpD OS=Coxiella burnetii GN=ahpD PE=3 SV=3	164.0	[0..3]	[169..2]
AHPD_HYPNA - Alkyl hydroperoxide reductase AhpD OS=Hyphomonas neptunium (strain ATCC 15444) GN=ahpD PE=3 SV=1	162.0	[0..1]	[163..1]
AHPD_MYCBO - Alkyl hydroperoxide reductase AhpD OS=Mycobacterium bovis GN=ahpD PE=3 SV=1 AHPD_MYCBO - Alkyl hydroperoxide reductase AhpD OS=Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) GN=ahpD ... AHPD_MYCTU - Alkyl hydroperoxide reductase AhpD OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) GN=ahpD... AHPD_MYCTO - Alkyl hydroperoxide reductase AhpD OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) GN=ahpD... gi\|215404367 - gi\|215404367\|ref\|ZP_03416548.1\| alkyl hydroperoxide reductase D protein ahpD [Mycobacterium tubercul... AHPD_MYCTU - Alkyl hydroperoxide reductase AhpD OS=Mycobacterium tuberculosis GN=ahpD PE=1 SV=1 gi\|215412185 - gi\|215412185\|ref\|ZP_03420949.1\| alkyl hydroperoxide reductase D protein ahpD [Mycobacterium tubercul... gi\|215446677 - gi\|215446677\|ref\|ZP_03433429.1\| alkyl hydroperoxide reductase D protein ahpD [Mycobacterium tubercul... gi\|218754161 - gi\|218754161\|ref\|ZP_03532957.1\| alkyl hydroperoxide reductase D protein ahpD [Mycobacterium tubercul... AHPD_MYCBT - Alkyl hydroperoxide reductase AhpD OS=Mycobacterium bovis (strain BCG / Tokyo 172 / ATCC 35737 / TMC... gi\|253798491, gi... - gi\|253798491\|ref\|YP_003031492.1\| alkyl hydroperoxide reductase D protein ahpD [Mycobacterium tubercu... gi\|254551480 - gi\|254551480\|ref\|ZP_05141927.1\| alkyl hydroperoxide reductase D protein ahpD [Mycobacterium tubercul... gi\|254816262 - gi\|254816262\|ref\|ZP_05221263.1\| alkyl hydroperoxide reductase D protein [Mycobacterium tuberculosis ... gi\|255097248 - gi\|255097248\|ref\|ZP_05326726.1\| alkyl hydroperoxide reductase D protein [Mycobacterium tuberculosis ... AHPD_MYCBP - Alkyl hydroperoxide reductase AhpD OS=Mycobacterium bovis (strain BCG / Pasteur 1173P2) GN=ahpD PE=3... gi\|119702254, gi... - gi\|76783733\|ref\|ZP_00770923.1\| COG2128: Uncharacterized conserved protein [Mycobacterium tuberculosi... gi\|194544618, gi... - gi\|81253606\|ref\|ZP_00878146.1\| COG2128: Uncharacterized conserved protein [Mycobacterium tuberculosi... gi\|134150720, gi... - gi\|254365206\|ref\|ZP_04981252.1\| alkyl hydroperoxide reductase D protein ahpD [Mycobacterium tubercul... AHPD_MYCTA - Alkyl hydroperoxide reductase AhpD OS=Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) GN=ahpD...	160.0	[0..1]	[175..1]

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Predicted Domain #1

Region A:
Residues: [1-177]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALDELKAAV PDYAKDLRLN LGSVIGNSDL PQQQLWGTVL ACAIASRSPR VLRELEPQAK  60
   61 ANLSPEAYTA AKSAAAIMAM NNVFYRTRHL LSDPEYGTLR AGLRMNVIGN PGVEKVDFEL 120
  121 WSLAVSAVNG CGQCLDSHEQ VLRKAGVDRD TIQEAFKIAA VIQAVGTTLD AEAVLAE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	39.69897
Match:	1gu9A
Description:	Antioxidant defence protein AhpD
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.832094458002337	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: