YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30260265, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	171 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30260265, gi|....

Description	E-value	Query Range	Subject Range
gi\|47570198, gi\|... - gi\|47570198\|ref\|ZP_00240852.1\| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin e pyrophosphokinase ...	8.0E-63	[1..171]	[1..171]
gi\|30018345, gi\|... - gi\|30018345\|ref\|NP_829976.1\| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase [Ba...	7.0E-62	[1..171]	[1..171]
gi\|218235679, gi... - gi\|218235679\|ref\|YP_002364924.1\| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase... gi\|75762251, gi\|... - gi\|75762251\|ref\|ZP_00742139.1\| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase [...	1.0E-61	[1..171]	[1..171]
gi\|89207173, gi\|... - gi\|89207173\|ref\|ZP_01185719.1\| 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK [Bacillus w...	8.0E-61	[1..171]	[1..171]
gi\|10172707, gi\|... - gi\|15612658\|ref\|NP_240961.1\| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin e pyrophosphokinase [B... gi\|25288328 - pir\|\|G83661 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin e pyrophosphokinase folK [imported] - B...	7.0E-60	[1..171]	[1..174]
gi\|89202206, gi\|... - gi\|89202206\|ref\|ZP_01180934.1\| 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK [Bacillus c...	8.0E-60	[1..171]	[1..171]
gi\|221312211 - gi\|221312211\|ref\|ZP_03594016.1\| 7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase [Bacillus subtil... gi\|221317144 - gi\|221317144\|ref\|ZP_03598438.1\| 7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase [Bacillus subtil... gi\|221321407 - gi\|221321407\|ref\|ZP_03602701.1\| 7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase [Bacillus subtil... HPPK_BACSU - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase OS=Bacillus subtilis GN=folK PE=... HPPK_BACSU - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase OS=Bacillus subtilis (strain 168...	2.0E-57	[1..171]	[1..167]
gi\|52078574, gi\|... - gi\|52783936\|ref\|YP_089765.1\| hypothetical protein BLi00095 [Bacillus licheniformis ATCC 14580], gi\|5...	2.0E-57	[1..171]	[1..166]
gi\|56961897, gi\|... - gi\|56961897\|ref\|YP_173619.1\| 7,8-dihydro-6-hydroxymethylpterin- pyrophosphokinase [Bacillus clausii ...	2.0E-56	[3..171]	[2..172]
gi\|56418606, gi\|... - gi\|56418606\|ref\|YP_145924.1\| 7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase (2-amino-4-hydroxy-...	5.0E-56	[1..171]	[1..175]

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Predicted Domain #1

Region A:
Residues: [1-171]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNNIAYIALG SNIGERYTYL TEAIQFLNKN PYIKVEDVSS VYETEPVGYT DQSCFLNLVI  60
   61 KISTNLSPQE LLKVTQKVEN DLGRKREIRW GPRTIDLDIL LYNQENIEAE NLIVPHPRMF 120
  121 ERAFVIVPLL EINQDIKQNI SRSQVEEMKR REGVTVWKQK NGEDAFVLFE N

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	53.154902
Match:	1dy3A
Description:	6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity	5.95418117400583	bayes_pls_golite062009
diphosphotransferase activity	4.79017391246148	bayes_pls_golite062009
catalytic activity	2.44295736158702	bayes_pls_golite062009
transferase activity	1.5312510694044	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.34283740138285	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: