YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30253738, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	372 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30253738, gi|....

Description	E-value	Query Range	Subject Range
gi\|47555878, gi\|... - gi\|47567476\|ref\|ZP_00238188.1\| 4-hydroxyphenylpyruvate dioxygenase [Bacillus cereus G9241], gi\|47555...	6.0E-85	[1..372]	[1..372]
gi\|89205757, gi\|... - gi\|89205757\|ref\|ZP_01184324.1\| 4-hydroxyphenylpyruvate dioxygenase [Bacillus weihenstephanensis KBAB...	6.0E-85	[1..372]	[1..372]
gi\|30018489, gi\|... - gi\|30018489\|ref\|NP_830120.1\| 4-hydroxyphenylpyruvate dioxygenase [Bacillus cereus ATCC 14579], gi\|29... gi\|206732844, gi... - gi\|206972270\|ref\|ZP_03233217.1\| 4-hydroxyphenylpyruvate dioxygenase [Bacillus cereus AH1134], gi\|206... gi\|218234156, gi... - gi\|218234156\|ref\|YP_002365067.1\| 4-hydroxyphenylpyruvate dioxygenase [Bacillus cereus B4264], gi\|218...	1.0E-84	[1..372]	[1..372]
gi\|75760149, gi\|... - gi\|75760149\|ref\|ZP_00740208.1\| 4-hydroxyphenylpyruvate dioxygenase [Bacillus thuringiensis serovar i...	4.0E-84	[1..372]	[18..389]
gi\|152974072, gi... - gi\|89200714\|ref\|ZP_01179465.1\| 4-hydroxyphenylpyruvate dioxygenase [Bacillus cereus subsp. cytotoxis...	4.0E-83	[1..372]	[1..372]
gi\|89098389, gi\|... - gi\|89098389\|ref\|ZP_01171273.1\| 4-hydroxyphenylpyruvate dioxygenase [Bacillus sp. NRRL B-14911], gi\|8...	6.0E-77	[1..372]	[1..371]
HPPD_STRAW - 4-hydroxyphenylpyruvate dioxygenase OS=Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM... HPPD_STRAW - 4-hydroxyphenylpyruvate dioxygenase OS=Streptomyces avermitilis GN=hpd PE=1 SV=2	1.0E-76	[1..372]	[1..381]
HPPD_STRCO - 4-hydroxyphenylpyruvate dioxygenase OS=Streptomyces coelicolor GN=hpd PE=3 SV=1 HPPD_STRCO - 4-hydroxyphenylpyruvate dioxygenase OS=Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) ...	1.0E-76	[1..372]	[1..381]
gi\|76164065, gi\|... - gi\|76261015\|ref\|ZP_00768638.1\| 4-hydroxyphenylpyruvate dioxygenase [Chloroflexus aurantiacus J-10-fl... gi\|53797468 - ref\|ZP_00358267.1\| COG3185: 4-hydroxyphenylpyruvate dioxygenase and related hemolysins [Chloroflexus... gi\|222524156, gi... - gi\|222524156\|ref\|YP_002568627.1\| 4-hydroxyphenylpyruvate dioxygenase [Chloroflexus sp. Y-400-fl], gi...	3.0E-76	[11..372]	[1..365]
gi\|108873353, gi... - gi\|157126195\|ref\|XP_001660843.1\| 4-hydroxyphenylpyruvate dioxygenase [Aedes aegypti], gi\|108873353\|g...	7.0E-76	[12..372]	[8..378]

Back

Predicted Domain #1

Region A:
Residues: [1-372]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKQKSMDTLA AQMEDFFPVR DVDHLEFYVG NAKQSSYYLA RAFGFKIVAY SGLETGNREK  60
   61 VSYVLVQKNM RFVVSGALSS DNRIAEFVKT HGDGVKDVAL LVDDVDKAYS EAVKRGAVAI 120
  121 APPVELTDEN GTLKKAVIGT YGDTIHTLVE RKNYKGTFMP GFQKAEFDIP FEESGLIAVD 180
  181 HVVGNVEKME EWVSYYENVM GFKQMIHFDD DDISTEYSAL MSKVMTNGSR IKFPINEPAD 240
  241 GKRKSQIQEY LEFYNGAGVQ HLALLTNDIV KTVEALRANG VEFLDTPDTY YDELTARVGK 300
  301 IDEEIDKLKE LKILVDRDDE GYLLQIFTKP IVDRPTLFIE IIQRKGSRGF GEGNFKALFE 360
  361 SIEREQERRG NL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	78.30103
Match:	1t47A
Description:	Structure of fe2-HPPD bound to NTBC
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
4-hydroxyphenylpyruvate dioxygenase activity	5.55625076505342	bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	2.26788314282577	bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	2.21815619779247	bayes_pls_golite062009
catalytic activity	1.21778090213032	bayes_pls_golite062009
binding	1.0574905568754	bayes_pls_golite062009
dioxygenase activity	0.768140787640544	bayes_pls_golite062009
protein binding	0.18929451652439	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: