YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30261635, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	279 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30261635, gi|....

Description	E-value	Query Range	Subject Range
PANB_BACWK - 3-methyl-2-oxobutanoate hydroxymethyltransferase OS=Bacillus weihenstephanensis (strain KBAB4) GN=pa... gi\|228617059, gi... - gi\|229166485\|ref\|ZP_04294241.1\| 3-methyl-2-oxobutanoate hydroxymethyltransferase [Bacillus cereus AH...	0.0	[1..278]	[1..278]
PANB_BACC1 - 3-methyl-2-oxobutanoate hydroxymethyltransferase OS=Bacillus cereus (strain ATCC 10987 / NRS 248) GN...	0.0	[1..278]	[1..278]
PANB_BACCR - 3-methyl-2-oxobutanoate hydroxymethyltransferase OS=Bacillus cereus (strain ATCC 14579 / DSM 31 / JC...	0.0	[1..278]	[1..278]
gi\|228900219, gi... - gi\|228900219\|ref\|ZP_04064450.1\| 3-methyl-2-oxobutanoate hydroxymethyltransferase [Bacillus thuringie... gi\|75760402, gi\|... - gi\|75760402\|ref\|ZP_00740446.1\| 3-methyl-2-oxobutanoate hydroxymethyltransferase [Bacillus thuringien...	0.0	[1..278]	[1..278]
PANB_BACCN - 3-methyl-2-oxobutanoate hydroxymethyltransferase OS=Bacillus cytotoxicus (strain DSM 22905 / CIP 110...	0.0	[1..278]	[1..278]
gi\|88926139, gi\|... - gi\|88944133\|ref\|ZP_01147466.1\| Ketopantoate hydroxymethyltransferase [Desulfotomaculum reducens MI-1...	0.0	[3..274]	[6..277]
gi\|147676555, gi... - gi\|98661989\|dbj\|GAA01057.1\| unnamed protein product [Pelotomaculum thermopropionicum SI], gi\|1476765...	0.0	[3..274]	[7..278]
gi\|65318905 - gi\|65318905\|ref\|ZP_00391864.1\| COG0413: Ketopantoate hydroxymethyltransferase [Bacillus anthracis st...	0.0	[10..279]	[1..270]
PANB_GEOKA - 3-methyl-2-oxobutanoate hydroxymethyltransferase OS=Geobacillus kaustophilus (strain HTA426) GN=panB... PANB_GEOKA - 3-methyl-2-oxobutanoate hydroxymethyltransferase OS=Geobacillus kaustophilus GN=panB PE=3 SV=1	0.0	[1..278]	[1..278]

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Predicted Domain #1

Region A:
Residues: [1-279]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTKTDFLKM KEQGEPITML TAYDYPSAKL AEEAEVDMIL VGDSLGMVVL GYDSTVPVTV  60
   61 EDMIHHTKAV RRGAKETFIV TDMPFMSYHV SLQDTMVNAR RIVQESGAHA LKVEGAGEVI 120
  121 STIHYLTNAG IPVVAHLGLT PQSVGVLGGY KVQGKDAESA KKLIEDAKKC EEAGAIALVL 180
  181 ECVPMQLAEL ISEQLTIPTI GIGAGQKVDG QVLVYHDLIS YGVNRVPKFV KQYTSVQEEI 240
  241 VRGISQYVAE VKTRQFPEEK HSFTMKEEEC LALYGGKQS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	108.0
Match:	1m3uA
Description:	Ketopantoate hydroxymethyltransferase PanB
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
3-methyl-2-oxobutanoate hydroxymethyltransferase activity	4.08693637310631	bayes_pls_golite062009
catalytic activity	2.59838799615646	bayes_pls_golite062009
hydroxymethyl-, formyl- and related transferase activity	2.05689968523792	bayes_pls_golite062009
transferase activity	1.07154136609184	bayes_pls_golite062009
glycine hydroxymethyltransferase activity	0.646649320021871	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.366715189574293	bayes_pls_golite062009
oxo-acid-lyase activity	0.0960362356555544	bayes_pls_golite062009
carbon-carbon lyase activity	0.0846611486307003	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: