YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30258532, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	259 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30258532, gi|....

Description	E-value	Query Range	Subject Range
PYRK_BACCN - Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit OS=Bacillus cytotoxicus (strain D...	2.0E-56	[1..259]	[1..259]
gi\|75763137, gi\|... - gi\|75763137\|ref\|ZP_00742910.1\| Dihydroorotate dehydrogenase electron transfer subunit [Bacillus thur...	2.0E-56	[1..259]	[1..259]
PYRK_BACCR - Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit OS=Bacillus cereus (strain ATCC 1...	3.0E-56	[1..259]	[1..259]
PYRK_BACWK - Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit OS=Bacillus weihenstephanensis (s...	7.0E-56	[1..259]	[1..259]
gi\|47553842, gi\|... - gi\|47569513\|ref\|ZP_00240193.1\| dihydroorotate dehydrogenase electron transfer subunit [Bacillus cere...	1.0E-55	[1..259]	[1..259]
PYRK_BACHD - Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit OS=Bacillus halodurans (strain AT... PYRK_BACHD - Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit OS=Bacillus halodurans GN=pyrK PE...	1.0E-53	[1..259]	[1..259]
PYRK_BACCL - Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit OS=Bacillus caldolyticus GN=pyrK ...	2.0E-53	[1..259]	[1..257]
PYRK_GEOKA - Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit OS=Geobacillus kaustophilus (stra... PYRK_GEOKA - Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit OS=Geobacillus kaustophilus GN=py...	2.0E-53	[1..259]	[1..257]
gi\|89098720, gi\|... - gi\|89098720\|ref\|ZP_01171602.1\| dihydroorotate dehydrogenase electron transfer subunit [Bacillus sp. ...	4.0E-52	[1..259]	[1..259]
PYRK_LISMO - Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit OS=Listeria monocytogenes GN=pyrK... gi\|224501365 - gi\|224501365\|ref\|ZP_03669672.1\| hypothetical protein LmonFR_02390 [Listeria monocytogenes FSL R2-561... PYRK_LISMO - Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit OS=Listeria monocytogenes serovar...	6.0E-52	[2..259]	[1..254]

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Predicted Domain #1

Region A:
Residues: [1-259]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMQKQNMIVV NQKEIAKNIY ELVLQGTLVQ QMNEPGQFVH IKVAEGIAPL LRRPISICNV  60
   61 DQEKNEFTML YRAEGQGTKT LATRKQGEMV DVLGPLGHGF PVEEAEAGQT ALLVGGGIGV 120
  121 PPLYELSQRL VAKGVRVIHI LGFQTKDVVF YEEKFAELGD TYVATVDGTH GTKGFVTDVI 180
  181 DHYGIDFDIL YSCGPLAMLR ALEGRYKEKK AYISLEERMG CGIGACFACV CHLQEDPSGH 240
  241 SYKKVCSDGP VFPIGEVVL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	39.69897
Match:	1ep3B
Description:	Dihydroorotate dehydrogenase B, PyrK subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.82418089257266	bayes_pls_golite062009
oxidoreductase activity	1.06930052685144	bayes_pls_golite062009
dihydroorotate dehydrogenase activity	0.67910028759775	bayes_pls_golite062009
transferase activity	0.20565726169867	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: