YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|7443722
Organism:	Helicobacter pylori
Length:	389 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7443722.

Description	E-value	Query Range	Subject Range
gi\|107837176, gi... - gi\|108563403\|ref\|YP_627719.1\| cyclopropane fatty acid synthase [Helicobacter pylori HPAG1], gi\|10783...	235.0	[0..1]	[389..1]
gi\|7443721 - pir\|\|B71865 cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79) - Helicobacter pylori (strai... gi\|4155557, gi\|1... - gi\|4155557\|gb\|AAD06552.1\| CYCLOPOCYCLOPROPANE FATTY ACID SYNTHASE [Helicobacter pylori J99], gi\|1561...	233.0	[0..1]	[389..1]
gi\|109714407, gi... - gi\|109947186\|ref\|YP_664414.1\| cyclopropane-fatty-acyl-phospholipid synthase [Helicobacter acinonychi...	230.0	[0..1]	[389..1]
gi\|11277873 - pir\|\|A81324 cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79) Cj1183c [similarity] - Campy... gi\|15792507, gi\|... - gi\|6968616\|emb\|CAB73437.1\| putative cyclopropane-fatty-acyl-phospholipid synthase [Campylobacter jej...	230.0	[0..1]	[389..1]
gi\|86150875, gi\|... - gi\|86150875\|ref\|ZP_01069091.1\| putative cyclopropane-fatty-acyl-phospholipid synthase protein [Campy...	228.0	[0..1]	[389..1]
gi\|21401332, gi\|... - gi\|65320695\|ref\|ZP_00393654.1\| COG2230: Cyclopropane fatty acid synthase and related methyltransfera...	220.0	[0..1]	[389..1]
gi\|57020435, gi\|... - gi\|57168061\|ref\|ZP_00367200.1\| cyclopropane fatty acid synthase (cfa) [Campylobacter coli RM2228], g...	219.0	[0..1]	[389..1]
gi\|86152995, gi\|... - gi\|86152995\|ref\|ZP_01071200.1\| cyclopropane fatty acid synthase [Campylobacter jejuni subsp. jejuni ...	219.0	[0..1]	[389..1]
gi\|86150286, gi\|... - gi\|86150286\|ref\|ZP_01068512.1\| cyclopropane-fatty-acyl-phospholipid synthase, putative [Campylobacte... gi\|153951326, gi... - gi\|153951326\|ref\|YP_001397721.1\| cyclopropane-fatty-acyl-phospholipid synthase, putative [Campylobac...	219.0	[0..1]	[389..1]
gi\|228916021, gi... - gi\|228916021\|ref\|ZP_04079594.1\| Cyclopropane-fatty-acyl-phospholipid synthase [Bacillus thuringiensi... gi\|227813763, gi... - gi\|227813763\|ref\|YP_002813772.1\| cyclopropane-fatty-acyl-phospholipid synthase [Bacillus anthracis s... gi\|254738450 - gi\|254738450\|ref\|ZP_05196153.1\| cyclopropane-fatty-acyl-phospholipid synthase [Bacillus anthracis st... gi\|254723381 - gi\|254723381\|ref\|ZP_05185169.1\| cyclopropane-fatty-acyl-phospholipid synthase [Bacillus anthracis st... gi\|254685978 - gi\|254685978\|ref\|ZP_05149837.1\| cyclopropane-fatty-acyl-phospholipid synthase [Bacillus anthracis st... gi\|229604349, gi... - gi\|229604349\|ref\|YP_002867621.1\| cyclopropane-fatty-acyl-phospholipid synthase [Bacillus anthracis s... gi\|254761279 - gi\|254761279\|ref\|ZP_05213303.1\| cyclopropane-fatty-acyl-phospholipid synthase [Bacillus anthracis st... gi\|254752766 - gi\|254752766\|ref\|ZP_05204802.1\| cyclopropane-fatty-acyl-phospholipid synthase [Bacillus anthracis st... gi\|254742385 - gi\|254742385\|ref\|ZP_05200070.1\| cyclopropane-fatty-acyl-phospholipid synthase [Bacillus anthracis st... gi\|190564577, gi... - gi\|190564577\|ref\|ZP_03017498.1\| cyclopropane-fatty-acyl-phospholipid synthase [Bacillus anthracis Ts... gi\|172084142, gi... - gi\|177650190\|ref\|ZP_02933191.1\| cyclopropane-fatty-acyl-phospholipid synthase [Bacillus anthracis st... gi\|170705206, gi... - gi\|170705206\|ref\|ZP_02895671.1\| cyclopropane-fatty-acyl-phospholipid synthase [Bacillus anthracis st... gi\|47528745, gi\|... - gi\|47528745\|ref\|YP_020094.1\| cyclopropane-fatty-acyl-phospholipid synthase [Bacillus anthracis str. ... gi\|170684969, gi... - gi\|170684969\|ref\|ZP_02876194.1\| cyclopropane-fatty-acyl-phospholipid synthase [Bacillus anthracis st... gi\|30263365, gi\|... - gi\|30263365\|ref\|NP_845742.1\| cyclopropane-fatty-acyl-phospholipid synthase [Bacillus anthracis str. ... gi\|167637453, gi... - gi\|167637453\|ref\|ZP_02395733.1\| cyclopropane-fatty-acyl-phospholipid synthase [Bacillus anthracis st... gi\|167532248, gi... - gi\|167631950\|ref\|ZP_02390277.1\| cyclopropane-fatty-acyl-phospholipid synthase [Bacillus anthracis st... gi\|164715055, gi... - gi\|165868329\|ref\|ZP_02212989.1\| cyclopropane-fatty-acyl-phospholipid synthase [Bacillus anthracis st... gi\|49186212, gi\|... - gi\|49186212\|ref\|YP_029464.1\| cyclopropane-fatty-acyl-phospholipid synthase [Bacillus anthracis str. ...	219.0	[0..1]	[389..1]

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Predicted Domain #1

Region A:
Residues: [1-309]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MISKFLLKSM FKQWKNGDYQ VVFWDNSVYR NGEHSPKFTL KIHRPLKFSD IKKDMSLTIA  60
   61 EAYMDGVIDI EGSMDEVMHS LYLQTNYEHL HKHDNAKAIQ KPIKESSNIS KHYDLGNDFY 120
  121 SIWLDETLSY SCAYFKKDDD TLHAAQLQKL DHTLKKLHLK PGEKLLDIGC GWGYLSVKAA 180
  181 QEYGAEVMGI TISSEQYKQA NKRVQELGLE DKVTIKLLNY QDLDGRLYRF DKVVSVGMFE 240
  241 HVGKDNLPFY FKKVKEVLKR GGMFLLHSIL CCFEGKTNAW VDKYIFPGGY LPSLREVMSV 300
  301 MSECDFHLL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	7.221849
Match:	1tw2A
Description:	Crystal structure of Carminomycin-4-O-methyltransferase (DnrK) in complex with S-adenosyl-L-homocystein (SAH) and 4-methoxy-e-rhodomycin T (M-ET)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.62377578202456	bayes_pls_golite062009
transferase activity	1.20063885869845	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	1.14636302691827	bayes_pls_golite062009
methyltransferase activity	1.12602040164126	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	0.535429947810431	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [310-389]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAESLRIHYA KTLDIWRNNF NHNLDQVKRL SYDERFIRMW DLYLRTCASA FRVGSADLFQ  60
   61 LLLTNSVDNT FPLTKEYIYQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	30.39794
Match:	1kp9A
Description:	CmaA1
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: