YRC Public Data Repository - Protein Structure Prediction

Protein:	ISPH_ARATH
Organism:	Arabidopsis thaliana
Length:	466 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ISPH_ARATH.

Description	E-value	Query Range	Subject Range
gi\|58761369 - gi\|58761369\|gb\|AAW82381.1\| chloroplast 1-hydroxy-2-methyl-butenyl 4-diphosphate reductase [Arabidops...	622.0	[0..1]	[466..1]
gi\|10716963 - gi\|10716963\|gb\|AAG21984.1\|AF270978_1 LYTB-like protein precursor [Adonis palaestina]	615.0	[0..1]	[466..1]
gi\|91255003 - gi\|91255003\|gb\|ABB88836.2\| IPP/DMAPP synthase [Stevia rebaudiana]	592.0	[0..1]	[466..1]
gi\|81076565 - gi\|81076565\|gb\|ABB55395.1\| LYTB-like protein precursor-like [Solanum tuberosum]	582.0	[0..1]	[466..1]
ISPH_ORYSJ - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, chloroplastic OS=Oryza sativa subsp. japonica GN...	560.0	[0..8]	[466..2]
gi\|85813153 - gi\|85813153\|gb\|ABC84344.1\| 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase [Ginkgo biloba]	544.0	[0..50]	[466..58]
gi\|25532849 - pir\|\|AF1929 hypothetical protein all0985 [imported] - Nostoc sp. (strain PCC 7120) ISPH_NOSS1 - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=is...	532.0	[0..58]	[463..2]
ISPH_SYNEL - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase OS=Synechococcus elongatus GN=ispH PE=3 SV=1 ISPH_THEEB - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase OS=Thermosynechococcus elongatus (strain BP-1) GN...	530.0	[0..58]	[463..2]
ISPH_ANAVT - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase OS=Anabaena variabilis (strain ATCC 29413 / PCC 7...	530.0	[0..58]	[463..2]

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Predicted Domain #1

Region A:
Residues: [1-119]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVALQFSRL CVRPDTFVRE NHLSGSGSLR RRKALSVRCS SGDENAPSPS VVMDSDFDAK  60
   61 VFRKNLTRSD NYNRKGFGHK EETLKLMNRE YTSDILETLK TNGYTYSWGD VTVKLAKAY

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [120-193]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GFCWGVERAV QIAYEARKQF PEERLWITNE IIHNPTVNKR LEDMDVKIIP VEDSKKQFDV  60
   61 VEKDDVVILP AFGA

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.857	N/A	N/A	c.84.1	Phosphoglucomutase, first 3 domains

Predicted Domain #3

Region A:
Residues: [194-303]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GVDEMYVLND KKVQIVDTTC PWVTKVWNTV EKHKKGEYTS VIHGKYNHEE TIATASFAGK  60
   61 YIIVKNMKEA NYVCDYILGG QYDGSSSTKE EFMEKFKYAI SKGFDPDNDL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [304-466]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VKVGIANQTT MLKGETEEIG RLLETTMMRK YGVENVSGHF ISFNTICDAT QERQDAIYEL  60
   61 VEEKIDLMLV VGGWNSSNTS HLQEISEARG IPSYWIDSEK RIGPGNKIAY KLHYGELVEK 120
  121 ENFLPKGPIT IGVTSGASTP DKVVEDALVK VFDIKREELL QLA

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.889	N/A	N/A	a.80.1	DNA polymerase III clamp loader subunits, C-terminal domain

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits