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View Structure Prediction Details

Protein: MCA7_ARATH
Organism: Arabidopsis thaliana
Length: 403 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MCA7_ARATH.

Description E-value Query
Range
Subject
Range
gi|32482818 - gi|32482818|gb|AAP84709.1| metacaspase 4 [Arabidopsis thaliana]
399.0 [0..1] [403..1]

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Predicted Domain #1
Region A:
Residues: [1-154]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKRALLIGI NYPGTTEELQ GCVNDVHRMH KCLVDRFGFA EEDITVLIDT DESYTQPTGK  60
   61 NIRQALSELI KPAKSGDVLF VHYSGHGTRV PPETGEEDDT GFDECIVPSD LNPIPDDDFR 120
  121 DLVEQVPEGC QITIVSDSCH SGGLIDEAKE QIGE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.69897
Match: 1rwkA
Description: Crystal structure of human caspase-1 in complex with 3-(2-mercapto-acetylamino)-4-oxo-pentanoic acid
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [155-403]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STTTKPNRES KVSSFEFEFK NCLHSIFVKL LAFCGIGSSH VETREIVEVG EGDEVVRSRY  60
   61 LPLERFIELL KQQTGQDNIE IGKIRPTLFD VFGEDSSPKI KKFMKVILTK LRKTNDQSTL 120
  121 LGKIEESARG YIEETLNDEH YMKPAMQAQV KSDREIYGGR SSNGLFPDRG ILLSGCQTDE 180
  181 TSADVKKKGE AFGAFSNAIQ MVLSETDHKD KITNKEMVLR AREILKKQMF IQRPGLYCND 240
  241 RFVNAPFIC

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.952
Match: 1jxqA
Description: Caspase-9
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.446816200197746 bayes_pls_golite062009
binding 0.128865592323915 bayes_pls_golite062009
hydrolase activity 0.00345801703057891 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle