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View Structure Prediction Details

Protein: MCA2_ARATH
Organism: Arabidopsis thaliana
Length: 418 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MCA2_ARATH.

Description E-value Query
Range
Subject
Range
gi|51968728, gi|... - gi|79325251|ref|NP_001031711.1| AtMC2 (metacaspase 2); cysteine-type endopeptidase [Arabidopsis thal...
372.0 [0..1] [418..1]

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Predicted Domain #1
Region A:
Residues: [1-125]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLLVDCSSC RTPLHLPPGA TRIRCAICHA FTLIAPEPRL QSHASASPFP FPNSSPAPST  60
   61 FIYPPPTPSP YTHAPHAPSP FNHAPPDSYP FTHAPPASSP FNHAPPGPPP PVHGQKRAVI 120
  121 VGVSY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.0
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [126-418]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KNTKDELKGC INDANCMKFM LMKRFQFPES CILMLTEEEA DPMRWPTKNN ITMAMHWLVL  60
   61 SCKPGDSLVF HFSGHGNNQM DDNGDEVDGF DETLLPVDHR TSGVIVDDEI NATIVRPLPY 120
  121 GVKLHAIVDA CHSGTVMDLP YLCRMDRLGN YEWEDHRPKT GMWKGTSGGE VFSFTGCDDD 180
  181 QTSADTPQLS GSAWTGAMTY AFIQAIERGH GMTYGSLLNA MRSTVHEIFD KNKGRELVEV 240
  241 GGADFLSTLL GLLILGASPP DEEEEVNQAP QKTQEPQLSA NEAFAVYEKP FSL

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.78
Match: 1jxqA
Description: Caspase-9
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.446816200197746 bayes_pls_golite062009
binding 0.128865592323915 bayes_pls_golite062009
hydrolase activity 0.00345801703057891 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle