YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|7451679
Organism:	Thermotoga maritima
Length:	201 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7451679.

Description	E-value	Query Range	Subject Range
gi\|134299758, gi... - gi\|88944800\|ref\|ZP_01148024.1\| Phosphoglycerate mutase/fructose-2,6-bisphosphatase [Desulfotomaculum...	190.0	[0..2]	[201..5]
gi\|146273747, gi... - gi\|98662370\|dbj\|GAA00697.1\| unnamed protein product [Pelotomaculum thermopropionicum SI], gi\|1476776...	185.0	[0..2]	[198..4]
GPMA_TREDE - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Treponema denticola GN=gpmA PE=3 SV=1 GPMA_TREDE - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Treponema denticola (strain ATCC 35405 ...	184.0	[0..1]	[200..1]
gi\|83572867, gi\|... - gi\|83589953\|ref\|YP_429962.1\| phosphoglycerate mutase [Moorella thermoacetica ATCC 39073], gi\|8357286...	182.0	[0..2]	[200..5]
gi\|15026080, gi\|... - gi\|15896273\|ref\|NP_349622.1\| phosphoglycerate mutase [Clostridium acetobutylicum ATCC 824], gi\|15026... gi\|25331550 - pir\|\|G97271 probable phosphoglycerate mutase [imported] - Clostridium acetobutylicum	180.0	[0..1]	[200..1]
gi\|7451675 - pir\|\|A70471 phosphoglycerate mutase 1 - Aquifex aeolicus gi\|15606984, gi\|... - gi\|2984221\|gb\|AAC07750.1\| phosphoglycerate mutase [Aquifex aeolicus VF5], gi\|15606984\|ref\|NP_214366....	179.0	[0..1]	[200..2]
gi\|47212179 - gi\|47212179\|emb\|CAF95127.1\| unnamed protein product [Tetraodon nigroviridis]	179.0	[0..2]	[200..6]
gi\|196252558, gi... - gi\|196252558\|ref\|ZP_03151214.1\| alpha-ribazole phosphatase [Clostridium thermocellum DSM 4150], gi\|1... gi\|125715856, gi... - gi\|67875683\|ref\|ZP_00504899.1\| Phosphoglycerate/bisphosphoglycerate mutase [Clostridium thermocellum...	179.0	[0..1]	[192..2]
gi\|68396928 - gi\|68396928\|ref\|XP_707183.1\| PREDICTED: similar to Phosphoglycerate mutase 2 (muscle) isoform 2 [Dan...	177.0	[0..2]	[200..6]
gi\|34763468, gi\|... - gi\|34763468\|ref\|ZP_00144413.1\| Phosphoglycerate mutase [Fusobacterium nucleatum subsp. vincentii ATC...	177.0	[0..1]	[190..1]

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Predicted Domain #1

Region A:
Residues: [1-201]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLYLIRHGE TIWNEKGLWQ GVTDVPLNER GREQARKLAN SLKRVDAIYS SPLKRSLETA  60
   61 EEIARRFEKE IIVEEDLREC EISLWNGLTV EEAIREYPVE FKKWSSDPNF GMEGLESMRN 120
  121 VQNRVVKAIM KIVSQEKLNG SENVVIVSHS LSLRAFICWI LGLPLYLHRN FKLDNASLSV 180
  181 VEIESKPRLV LLNDTCHLKE S

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	44.154902
Match:	1xq9A
Description:	Structure of Phosphoglycerate Mutase from Plasmodium falciparum at 2.6 Resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phosphoglycerate mutase activity	2.29687410980387	bayes_pls_golite062009
phosphofructokinase activity	2.18786740610088	bayes_pls_golite062009
6-phosphofructo-2-kinase activity	1.92518572666112	bayes_pls_golite062009
fructose-2,6-bisphosphate 2-phosphatase activity	1.57622840153679	bayes_pls_golite062009
catalytic activity	1.37714494241232	bayes_pls_golite062009
hydrolase activity	0.959714350381009	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.924447963448235	bayes_pls_golite062009
intramolecular transferase activity, phosphotransferases	0.916759493094631	bayes_pls_golite062009
binding	0.911287540615709	bayes_pls_golite062009
carbohydrate kinase activity	0.815187968645556	bayes_pls_golite062009
carbohydrate phosphatase activity	0.542850952800002	bayes_pls_golite062009
isomerase activity	0.275500708652009	bayes_pls_golite062009
intramolecular transferase activity	0.17180601190736	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: