YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|7450156
Organism:	Thermotoga maritima
Length:	123 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7450156.

Description	E-value	Query Range	Subject Range
gi\|119720590, gi... - gi\|119720590\|ref\|YP_921085.1\| HEPN domain-containing protein [Thermofilum pendens Hrk 5], gi\|1195257...	149.0	[0..1]	[123..11]
gi\|30749838 - gi\|30749838\|pdb\|1O3U\|A Chain A, Crystal Structure Of An Hepn Domain Protein (Tm0613) From Thermotoga...	148.0	[0..1]	[123..13]
gi\|222526711, gi... - gi\|222526711\|ref\|YP_002571182.1\| HEPN domain protein [Chloroflexus sp. Y-400-fl], gi\|222450590\|gb\|AC... gi\|76164494, gi\|... - gi\|76260577\|ref\|ZP_00768210.1\| HEPN [Chloroflexus aurantiacus J-10-fl], gi\|76164494\|gb\|EAO58641.1\| H...	147.0	[0..2]	[121..10]
gi\|18161127, gi\|... - gi\|18313583\|ref\|NP_560250.1\| hypothetical protein PAE2783 [Pyrobaculum aerophilum str. IM2], gi\|1816...	140.0	[0..4]	[120..17]
gi\|7518627 - pir\|\|H71148 hypothetical protein PH0402 - Pyrococcus horikoshii gi\|3256794, gi\|1... - gi\|3256794\|dbj\|BAA29477.1\| 140aa long hypothetical protein [Pyrococcus horikoshii OT3], gi\|14590309\|...	137.0	[0..3]	[123..15]
gi\|48852699 - ref\|ZP_00306883.1\| COG2250: Uncharacterized conserved protein related to C-terminal domain of eukary... gi\|68140719, gi\|... - gi\|69268873\|ref\|ZP_00609505.1\| HEPN [Ferroplasma acidarmanus Fer1], gi\|68140719\|gb\|EAM94016.1\| HEPN ...	137.0	[0..1]	[121..9]
gi\|241217282, gi... - gi\|241771063\|ref\|ZP_04768454.1\| HEPN domain protein [Sulfolobus solfataricus 98/2], gi\|241217282\|gb\|... gi\|13815092, gi\|... - gi\|15898635\|ref\|NP_343240.1\| hypothetical protein SSO1834 [Sulfolobus solfataricus P2], gi\|13815092\|... gi\|25326719 - pir\|\|G90346 conserved hypothetical protein [imported] - Sulfolobus solfataricus	136.0	[0..1]	[120..9]
gi\|55772022, gi\|... - gi\|55980609\|ref\|YP_143906.1\| hypothetical protein TTHA0640 [Thermus thermophilus HB8], gi\|55772022\|d...	135.0	[0..1]	[120..8]
gi\|83753524, gi\|... - gi\|83753524\|pdb\|1WOL\|A Chain A, Crystal Structure Of St0689, An Archaeal Hepn Homologue, gi\|15920917...	134.0	[0..2]	[121..9]

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Predicted Domain #1

Region A:
Residues: [1-123]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDAAKDDLEH AKHDLEHGFY NWACFSSQQA AEKAVKAVFQ RMGAQAWGYS VPDFLGELSS  60
   61 RFEIPEELMD HALELDKACI PTRYPDALPS GSPRNRYSRI EAERLVNYAE KIIRFCEDLL 120
  121 SRI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	36.69897
Match:	1o3uA
Description:	Hypothetical protein TM0613
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.372436499192166	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: