YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|23466233, gi\|...
Organism:	Bifidobacterium longum NCC2705
Length:	470 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|23466233, gi|....

Description	E-value	Query Range	Subject Range
gi\|23336230, gi\|... - gi\|23336230\|ref\|ZP_00121455.1\| COG0801: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase [Bifidob...	0.0	[1..470]	[1..470]
gi\|119025430, gi... - gi\|119025430\|ref\|YP_909275.1\| aldolase-pyrophosphokinase [Bifidobacterium adolescentis ATCC 15703], ... gi\|85666508 - gi\|85666508\|ref\|ZP_01028732.1\| hypothetical protein Badol_01001353 [Bifidobacterium adolescentis]	0.0	[1..470]	[1..515]
gi\|27886451, gi\|... - gi\|34763775\|ref\|ZP_00144691.1\| Dihydroneopterin aldolase; 2-amino-4-hydroxy-6-hydroxymethyldihydropt...	5.0E-88	[1..286]	[1..271]
gi\|19703424, gi\|... - gi\|19713498\|gb\|AAL94285.1\| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase [Fuso...	2.0E-86	[1..286]	[1..271]
gi\|82722943, gi\|... - gi\|82749218\|ref\|ZP_00911682.1\| 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK:Dihydroneop...	2.0E-80	[1..275]	[1..261]
gi\|18144683, gi\|... - gi\|18310004\|ref\|NP_561938.1\| dihydroneopterin aldolase/ 2-amino-4-hydroxy-6-hydroxymethyldihydropter...	2.0E-80	[1..284]	[1..269]
FOL1_PNECA - Folic acid synthesis protein fol1 OS=Pneumocystis carinii GN=fol1 PE=1 SV=1	3.0E-80	[2..289]	[161..447]
gi\|110682789, gi... - gi\|110802288\|ref\|YP_698421.1\| dihydroneopterin aldolase/ 2-amino-4-hydroxy-6-hydroxymethyldihydropte...	6.0E-80	[1..284]	[1..269]
gi\|110798735, gi... - gi\|110798735\|ref\|YP_695723.1\| dihydroneopterin aldolase/ 2-amino-4-hydroxy-6-hydroxymethyldihydropte...	7.0E-80	[1..284]	[1..269]
gi\|62423730 - gi\|62423730\|ref\|ZP_00378887.1\| COG0801: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase [Breviba...	2.0E-79	[2..294]	[6..307]

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Predicted Domain #1

Region A:
Residues: [1-300]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDTITLTGVH ANGTHGVLAF EHERPQTFVV DVTLHLDLAA AGQSDDLNDT IDYGRVAKDI  60
   61 VAVIEGPHVD LIERLAQRIA DKILADAPAV ASIDVTVHKP HAPIVVAFAD VSVSISRVRA 120
  121 TDNGRTAEKH AIHNAVVALG GNVGEVESTL RAAVREIDAL LGTQVTGISP LYRTAAWGMA 180
  181 DGTPDFLNAV VELGTTMGRH ELLAALQNIE ANHGRIRENH WDSRPLDLDI IDFDGITSAD 240
  241 PDLALPHPRA WQRAFVLAPW LALNPNAKLA GAHEGPVADL LAAAPDRNAV QLESEDWMLG 300
  301

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	75.522879
Match:	2cg8A
Description:	No description for 2cg8A was found.

Predicted Domain #2

Region A:
Residues: [301-470]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GHAVKQKSAS ESAPVSRKAI ISLDSTSQDA ERLFRETIVS IDSVPGNQVQ GISPLYHVSH  60
   61 FDSPDAMSAV IQIETKLPPA DLIAVLGSIE SVHDLAVDLD LVDMEGVTSD EPNCSIPWPS 120
  121 ARNHASVLAP WLDMDPNASL GGDPVAFLLA MAPDAGQVGL LSDNWILSNS

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	7.58
Match:	1dy3A
Description:	6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity	5.12226854473043	bayes_pls_golite062009
diphosphotransferase activity	4.07506436089142	bayes_pls_golite062009
catalytic activity	2.27740893348637	bayes_pls_golite062009
transferase activity	1.25509982990376	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.00042775922629	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: