YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|7473474
Organism:	Deinococcus radiodurans
Length:	698 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7473474.

Description	E-value	Query Range	Subject Range
gi\|46107656, gi\|... - gi\|46107656\|ref\|XP_380887.1\| hypothetical protein FG00711.1 [Gibberella zeae PH-1], gi\|42547814\|gb\|E...	2.0E-68	[5..561]	[1416..1972]
gi\|66781862, gi\|... - gi\|94972141\|ref\|YP_594181.1\| EmrB/QacA family drug resistance transporter [Deinococcus geothermalis ...	9.0E-65	[15..687]	[2..675]
gi\|60467752, gi\|... - gi\|60467752\|gb\|EAL65769.1\| hypothetical protein DDB0191430 [Dictyostelium discoideum], gi\|29500764\|g... gi\|60467752, gi\|... - gi\|66810832\|ref\|XP_639123.1\| major facilitator superfamily transporter [Dictyostelium discoideum AX4...	1.0E-63	[27..528]	[595..1096]
gi\|21225257, gi\|... - gi\|7649556\|emb\|CAB89031.1\| putative membrane transport protein. [Streptomyces coelicolor A3(2)], gi\|...	2.0E-63	[6..597]	[5..588]
gi\|54014576, gi\|... - gi\|54023068\|ref\|YP_117310.1\| putative transporter [Nocardia farcinica IFM 10152], gi\|54014576\|dbj\|BA...	1.0E-58	[16..571]	[4..548]
gi\|76258618, gi\|... - gi\|76258618\|ref\|ZP_00766272.1\| Drug resistance transporter EmrB/QacA subfamily [Chloroflexus auranti...	2.0E-58	[44..678]	[42..613]
gi\|46198933, gi\|... - gi\|46198933\|ref\|YP_004600.1\| multidrug resistance protein B [Thermus thermophilus HB27], gi\|46196557...	1.0E-57	[27..683]	[5..620]
gi\|49648930 - gi\|49648930\|emb\|CAG81254.1\| YALI0D20196p [Yarrowia lipolytica] gi\|50551177, gi\|... - gi\|50551177\|ref\|XP_503062.1\| YALI0D20196p [Yarrowia lipolytica], gi\|49648930\|emb\|CAG81254.1\| unnamed...	3.0E-57	[2..534]	[21..564]
gi\|38110405, gi\|... - gi\|39952271\|ref\|XP_363852.1\| hypothetical protein MGG_01778 [Magnaporthe grisea 70-15], gb\|EAA56127....	7.0E-55	[5..597]	[66..632]
gi\|90196450, gi\|... - gi\|90204398\|ref\|ZP_01207041.1\| Drug resistance transporter EmrB/QacA subfamily [Mycobacterium vanbaa...	2.0E-54	[9..523]	[2..504]

Back

Predicted Domain #1

Region A:
Residues: [1-536]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTNPASPPLQ SSPAPVPVPD HETMPHFTDQ EKRITLIGLL VVFLLAALSQ NVVGTAMPRI  60
   61 IEDLKGFNLY TWVTTAYLLA STVMVPIYGK LSDLYGRKPI LIFGILVFLF GSALCGLAGE 120
  121 PFLGNFLGGG MNQLIAFRAV AGFGGAALFT TAFTILADMF DPTERAKFGG LFGAIFGLSM 180
  181 VLGPLIGGWL TDTLSWRWTF YANLPLGILA LFLIISKMPK LAHRMQGKID YWGAALILAT 240
  241 TIPLLLALTW GGTTYAWNSS TIISLFAGSL VSLIAFLFVE RRTPDAIIPL TLFNVPMFSI 300
  301 GNLASFVMGM AFFGVVMFLP LYMQMVLGVS PTASGTSMLP LMLGLMLSSI TSGNIVARTG 360
  361 KYKPWMIGGA LILILGMWTL TGIRSDSHLV DLYWRMFIVG LGLGPSQSLF TLAIQSAVPL 420
  421 RQLGVATSSS QFFRQIGSTI GAAIFGTLLM NNLHNELPKH LPAMPGSSMN SKNIDLGTLR 480
  481 AASTGKGNGP EVQIKKAFDQ QYVLIEKAIN GDEAARRAVQ ANKQLPNELK VLATGG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	31.154902
Match:	1pw4A
Description:	Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transporter activity	4.09176719149278	bayes_pls_golite062009
substrate-specific transporter activity	3.59744164024479	bayes_pls_golite062009
transmembrane transporter activity	3.5865018981083	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	3.54194478414824	bayes_pls_golite062009
ion transmembrane transporter activity	2.21266150105753	bayes_pls_golite062009
organic acid transmembrane transporter activity	2.15783210522667	bayes_pls_golite062009
cation transmembrane transporter activity	1.79369588808394	bayes_pls_golite062009
active transmembrane transporter activity	1.59419818573076	bayes_pls_golite062009
secondary active transmembrane transporter activity	1.22264637452409	bayes_pls_golite062009
binding	1.01584233411372	bayes_pls_golite062009
polyol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
alcohol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
glycerol transmembrane transporter activity	0.812001619402678	bayes_pls_golite062009
symporter activity	0.74591237387473	bayes_pls_golite062009
solute:cation symporter activity	0.74591237387473	bayes_pls_golite062009
cation:sugar symporter activity	0.143419068761182	bayes_pls_golite062009
sugar:hydrogen symporter activity	0.143419068761182	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [537-698]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNAKVHAGVI RQAAGVQAAL AKGEKGRQAI LRNPNRPEQL KAIVRGLPAQ ALATPQAAQV  60
   61 TAARVAQGIL ASEPQVQAQA RTQALATIKQ QFDTQAKTLG KQVGQGLKDG FTASMTKMFR 120
  121 SAIWFALAGF LITLFVPVVP LRTRNKPAGP SKTEGEGAVP VA

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: