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View Structure Prediction Details

Protein: gi|15674399, gi|...
Organism: Streptococcus pyogenes M1 GAS
Length: 290 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|15674399, gi|....

Description E-value Query
Range
Subject
Range
gi|146296784, gi... - gi|82500738|ref|ZP_00886138.1| Nicotinate-nucleotide pyrophosphorylase [Caldicellulosiruptor sacchar...
298.0 [0..8] [286..2]

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Predicted Domain #1
Region A:
Residues: [1-290]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIISTDLTP FQIDDTLKAA LREDVHSEDY STNAIFDHHG QAKVSLFAKE AGVLAGLTVF  60
   61 QRVFTLFDTE VTFQNPHQFK DGDRLTSGDL VLEIIGSVRS LLTCERVALN FLQHLSGIAS 120
  121 MTAAYVEALG DDRIKVFDTR KTTPNLRLFE KYAVRVGGGY NHRFNLSDAI MLKDNHIAAV 180
  181 GSVQKAIAQA RAYAPFVKMV EVEVESLAAA EEAAAAGVDI IMLDNMSLEQ IEQAITLIAG 240
  241 RSRIECSGNI DMTTISRFRG LAIDYVSSGS LTHSAKSLDF SMKGLTYLDV 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 73.0
Match: 1qapA
Description: Quinolinic acid phosphoribosyltransferase (Nicotinate-nucleotide pyrophosphorylase, NadC), C-terminal domain; Quinolinic acid phosphoribosyltransferase (Nicotinate-nucleotide pyrophosphorylase, NadC), N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nicotinate phosphoribosyltransferase activity 3.4096751090496 bayes_pls_golite062009
nicotinate-nucleotide diphosphorylase (carboxylating) activity 3.12788282156037 bayes_pls_golite062009
binding 1.58263447797054 bayes_pls_golite062009
catalytic activity 0.60409960326459 bayes_pls_golite062009
protein binding 0.502035039039958 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle