YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|2105045, gi\|1...
Organism:	Mycobacterium tuberculosis H37Rv
Length:	771 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|2105045, gi|1....

Description	E-value	Query Range	Subject Range
gi\|215447985 - gi\|215447985\|ref\|ZP_03434737.1\| putative helicase [Mycobacterium tuberculosis T85] gi\|215432622 - gi\|215432622\|ref\|ZP_03430541.1\| putative helicase [Mycobacterium tuberculosis EAS054] gi\|215413569 - gi\|215413569\|ref\|ZP_03422241.1\| putative helicase [Mycobacterium tuberculosis 94_M4241A] gi\|215405696 - gi\|215405696\|ref\|ZP_03417877.1\| putative helicase [Mycobacterium tuberculosis 02_1987] gi\|31794819, gi\|... - gi\|31794819\|ref\|NP_857312.1\| putative helicase [Mycobacterium bovis AF2122/97], gi\|31620416\|emb\|CAD9...	580.0	[0..1]	[771..1]
gi\|15843261, gi\|... - gi\|15843261\|ref\|NP_338298.1\| DEAD-box ATP dependent DNA helicase [Mycobacterium tuberculosis CDC1551...	577.0	[0..1]	[771..1]
gi\|4539568, gi\|2... - gi\|4539568\|emb\|CAB38487.1\| putative helicase [Streptomyces coelicolor A3(2)], gi\|21221969\|ref\|NP_627... gi\|7480744 - pir\|\|T36671 probable helicase - Streptomyces coelicolor	557.0	[0..8]	[771..40]
gi\|29831156, gi\|... - gi\|29831156\|ref\|NP_825790.1\| ATP-dependent RNA helicase [Streptomyces avermitilis MA-4680], gi\|29608...	549.0	[0..12]	[769..53]
gi\|41406520, gi\|... - gi\|41406520\|ref\|NP_959356.1\| hypothetical protein MAP0422c [Mycobacterium avium subsp. paratuberculo...	538.0	[0..1]	[771..1]
gi\|108772181, gi... - gi\|108801762\|ref\|YP_641959.1\| DEAD/DEAH box helicase-like protein [Mycobacterium sp. MCS], gi\|108772... gi\|92438053, gi\|... - gi\|92917823\|ref\|ZP_01286432.1\| Helicase-like:DEAD/DEAH box helicase-like [Mycobacterium sp. KMS], gi...	523.0	[0..1]	[764..1]
gi\|92906892, gi\|... - gi\|92906892\|ref\|ZP_01275672.1\| Helicase-like:DEAD/DEAH box helicase-like [Mycobacterium sp. JLS], gi...	523.0	[0..1]	[763..1]
gi\|89340502, gi\|... - gi\|89340502\|ref\|ZP_01192759.1\| Helicase-like:DEAD/DEAH box helicase-like [Mycobacterium flavescens P...	521.0	[0..4]	[764..8]
gi\|23492141, gi\|... - gi\|25026861\|ref\|NP_736915.1\| hypothetical protein CE0305 [Corynebacterium efficiens YS-314], gi\|2349...	517.0	[0..3]	[763..114]

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Predicted Domain #1

Region A:
Residues: [1-576]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASFGSHLLA AAVAGTPPGE RPLRHVAELP PQAGRPRGWP EWAEPDVVDA FADRGISSPW  60
   61 SHQAEAAELA YAGRHVVIGT GPASGKSLAY QLLVLNALAT DSRARALYLS PTKALGHDQL 120
  121 RAAHALAAAV PRLADVAPTA YDGDSPDEVR RFARERSRWL FSNPEMTHLS VLRNHARWAV 180
  181 LLRNLRFVIV DECHYYRGVF GSNVAMVLRR LLRLCARYSA HPTVIFASAT TASPGATAAD 240
  241 LIGQPVVEVT EDGSPRGART VALWEPALRS DVIGEHGAPV RRSAGAEAAR VMADLIVEGA 300
  301 QTLTFVRSRR AAELTALGAR ARLVDIAPEL SDTVASYRAG YLAEDRSALH QALAEGQLRG 360
  361 LATTNALELG VDIAGLDAVV LAGFPGTVAS FWQQAGRSGR RGQGALVVLI ARDDPLDTYL 420
  421 VHHPAALLDK PVERVVIDPV NPHLLGPQLL CAATELPLDD AEVRSWGAVE VAESLVDDGL 480
  481 LRRRNGRYFP APGVKPHAAV DVRGAIGGQI VIVEAGTGRL LGSVGVGQAP AAAHPGAVYL 540
  541 HQGETYVVDS LDFQDGIAFV HAEDPGYATF AREVTD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	51.09691
Match:	1oywA
Description:	Structure of the RecQ Catalytic Core
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.37148167194523	bayes_pls_golite062009
hydrolase activity	0.226001870533921	bayes_pls_golite062009
transcription factor activity	0.219681379631971	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [577-655]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IAVTGTGERL VFGPVALGLV PVTVTNHVVG YLRRQLSGEV LDFVELDMPE HTLPTTAVMY  60
   61 TITSDALVRS GIEATRIPG

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [656-771]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLHAAEHAAI GLLPLVASCD RGDIGGMSTA TGPEGLPSVF VYDGYPGGAG FAERGFRRAR  60
   61 TWLGATAEAI EACECPSGCP SCVQSPKCGN GNDPLDKAGA VRVLRLVLAE LSEESP

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	31.958607
Match:	PF09369.1
Description:	No description for PF09369.1 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: