YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|7477880
Organism:	Mycobacterium tuberculosis
Length:	500 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7477880.

Description	E-value	Query Range	Subject Range
gi\|123213964, gi... - gi\|76785702\|ref\|ZP_00772866.1\| COG2234: Predicted aminopeptidases [Mycobacterium tuberculosis F11], ...	340.0	[0..7]	[500..1]
gi\|15839805, gi\|... - gi\|15839805\|ref\|NP_334842.1\| hydrolase [Mycobacterium tuberculosis CDC1551], gi\|13879936\|gb\|AAK44656...	339.0	[0..20]	[500..13]
gi\|41410004, gi\|... - gi\|41410004\|ref\|NP_962840.1\| LpqL_1 [Mycobacterium avium subsp. paratuberculosis K-10], gi\|41398837\|...	327.0	[0..1]	[499..1]
gi\|92432730, gi\|... - gi\|92909563\|ref\|ZP_01278340.1\| Lysyl aminopeptidase [Mycobacterium sp. JLS], gi\|92432730\|gb\|EAS92064...	297.0	[0..1]	[495..1]
gi\|108797533, gi... - gi\|108797533\|ref\|YP_637730.1\| aminopeptidase Y [Mycobacterium sp. MCS], gi\|108767952\|gb\|ABG06674.1\| ... gi\|119866619, gi... - gi\|92916047\|ref\|ZP_01284668.1\| Lysyl aminopeptidase [Mycobacterium sp. KMS], gi\|92439731\|gb\|EAS97577...	294.0	[0..1]	[495..1]
gi\|89338802, gi\|... - gi\|89338802\|ref\|ZP_01191567.1\| Peptidase M20:Protease-associated PA:Peptidase M28 [Mycobacterium fla...	294.0	[0..45]	[500..52]
gi\|90205903, gi\|... - gi\|90205903\|ref\|ZP_01208541.1\| Lysyl aminopeptidase [Mycobacterium vanbaalenii PYR-1], gi\|90195340\|g...	287.0	[0..23]	[500..22]
gi\|85085428 - gi\|85085428\|ref\|XP_957507.1\| hypothetical protein NCU04430 [Neurospora crassa OR74A] gi\|40882190, gi\|... - gi\|40882190\|emb\|CAF06016.1\| related to aminopeptidase Y precursor, vacuolar [Neurospora crassa], gi\|...	285.0	[0..40]	[486..29]
gi\|111019178, gi... - gi\|111019178\|ref\|YP_702150.1\| aminopeptidase [Rhodococcus jostii RHA1], gi\|110818708\|gb\|ABG93992.1\| ...	284.0	[0..34]	[498..8]
gi\|42551960, gi\|... - gi\|46120810\|ref\|XP_385112.1\| hypothetical protein FG04936.1 [Gibberella zeae PH-1], gi\|42551960\|gb\|E...	281.0	[0..24]	[497..4]

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Predicted Domain #1

Region A:
Residues: [1-149]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVNKSRMMPA VLAVAVVVAF LTTGCIRWST QSRPVVNGPA AAEFAVALRN RVSTDAMMAH  60
   61 LSKLQDIANA NDGTRAVGTP GYQASVDYVV NTLRNSGFDV QTPEFSARVF KAEKGVVTLG 120
  121 GNTVEARALE YSLGTPPDGV TGPLVAAPA

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	2.04
Match:	2ootA
Description:	No description for 2ootA was found.

Predicted Domain #2

Region A:
Residues: [150-208]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDSPGCSPSD YDRLPVSGAV VLVDRGVCPF AQKEDAAAQR GAVALIIADN IDEQAMGGT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	3.522879
Match:	1xf1A
Description:	Structure of C5a peptidase- a key virulence factor from Streptococcus
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [209-500]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGANTDVKIP VVSVTKSVGF QLRGQSGPTT VKLTASTQSF KARNVIAQTK TGSSANVVMA  60
   61 GAHLDSVPEG PGINDNGSGV AAVLETAVQL GNSPHVSNAV RFAFWGAEEF GLIGSRNYVE 120
  121 SLDIDALKGI ALYLNFDMLA SPNPGYFTYD GDQSLPLDAR GQPVVPEGSA GIERTFVAYL 180
  181 KMAGKTAQDT SFDGRSDYDG FTLAGIPSGG LFSGAEVKKS AEQAELWGGT ADEPFDPNYH 240
  241 QKTDTLDHID RTALGINGAG VAYAVGLYAQ DLGGPNGVPV MADRTRHLIA KP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	43.522879
Match:	1cp7A
Description:	Aminopeptidase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.868869462173853	bayes_pls_golite062009
hydrolase activity	0.66015973787775	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: