YRC Public Data Repository - Protein Structure Prediction

Protein:	PNCB2_PSEAE
Organism:	Pseudomonas aeruginosa PAO1
Length:	398 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PNCB2_PSEAE.

Description	E-value	Query Range	Subject Range
gi\|60594388, gi\|... - gi\|60594391\|pdb\|1YIR\|D Chain D, Crystal Structure Of A Nicotinate Phosphoribosyltransferase, gi\|6059...	0.0	[3..398]	[5..400]
gi\|94415489, gi\|... - gi\|94415489\|ref\|ZP_01295329.1\| hypothetical protein PaerP_01002652 [Pseudomonas aeruginosa PA7], gi\|...	0.0	[1..398]	[1..398]
gi\|84317541 - gi\|84317541\|ref\|ZP_00965981.1\| COG1488: Nicotinic acid phosphoribosyltransferase [Pseudomonas aerugi...	0.0	[1..397]	[3..399]
gi\|218894014, gi... - gi\|218894014\|ref\|YP_002442883.1\| nicotinate phosphoribosyltransferase [Pseudomonas aeruginosa LESB58... PNCB1_PSEAE, PNB... - Nicotinate phosphoribosyltransferase 1 OS=Pseudomonas aeruginosa GN=pncB1 PE=3 SV=1, (Q9HUP4) Nicoti... PNCB1_PSEAE - Nicotinate phosphoribosyltransferase 1 OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PR... gi\|53726497, gi\|... - gi\|53726497\|ref\|ZP_00141393.2\| COG1488: Nicotinic acid phosphoribosyltransferase [Pseudomonas aerugi... gi\|107104018 - gi\|107104018\|ref\|ZP_01367936.1\| hypothetical protein PaerPA_01005091 [Pseudomonas aeruginosa PACS2] gi\|254238363, gi... - gi\|254238363\|ref\|ZP_04931686.1\| nicotinate phosphoribosyltransferase [Pseudomonas aeruginosa C3719],...	0.0	[1..397]	[1..397]
gi\|84323740 - gi\|84323740\|ref\|ZP_00971808.1\| COG1488: Nicotinic acid phosphoribosyltransferase [Pseudomonas aerugi...	0.0	[1..397]	[3..399]
PNCB_PSE14 - Nicotinate phosphoribosyltransferase OS=Pseudomonas savastanoi pv. phaseolicola (strain 1448A / Race...	0.0	[1..397]	[1..397]
PNCB_PSEU2 - Nicotinate phosphoribosyltransferase OS=Pseudomonas syringae pv. syringae (strain B728a) GN=pncB PE=...	0.0	[1..397]	[1..397]
PNCB_PSEPF - Nicotinate phosphoribosyltransferase OS=Pseudomonas fluorescens (strain Pf0-1) GN=pncB PE=3 SV=1	0.0	[1..397]	[1..397]
PNCB_PSESM - Nicotinate phosphoribosyltransferase OS=Pseudomonas syringae pv. tomato (strain DC3000) GN=pncB PE=3... PNCB_PSESM - Nicotinate phosphoribosyltransferase OS=Pseudomonas syringae pv. tomato GN=pncB PE=3 SV=1	0.0	[1..397]	[1..397]

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Predicted Domain #1

Region A:
Residues: [1-398]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAESAFSERI VQNLLDTDFY KLTMMQAVLH NYPNAEVEWE FRCRNQEDLR LYLPAIREQL  60
   61 EYLAGLAISD EQLAFLERIP FLAPDFIRFL GLFRFNPRYV QTGIENDEFF LRLKGPWLHV 120
  121 ILFEVPLLAM ISEVRNRARY PAATVEQARE RLQEKFDWLR REASAEELAG FKMADFGTRR 180
  181 RFSYRVHEAV VSGLKEDFPG CFVGTSNVHL ARKLDLKPLG TMAHEWLMAH QQLGPRLIDS 240
  241 QSAALDCWVR EYRGLLGIAL TDCITTDAFL RDFDLYFAKL FDGLRHDSGD PLLWAEKTIA 300
  301 HYLKLGIDPL TKTLVFSDGL DLPRALKIYR ALQGRINVSF GIGTHFTCDL PGVEPMNIVV 360
  361 KMSACNGHPV AKISDTPGKA QCRDPDFIHY LKHVFQVA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	128.0
Match:	1yirA
Description:	Crystal Structure of a Nicotinate Phosphoribosyltransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nicotinate phosphoribosyltransferase activity	5.75487746784842	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	4.79136593406808	bayes_pls_golite062009
nicotinate-nucleotide diphosphorylase (carboxylating) activity	3.97201856258863	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	3.41342374351311	bayes_pls_golite062009
catalytic activity	2.59603106157451	bayes_pls_golite062009
transferase activity	1.91642626258277	bayes_pls_golite062009
binding	1.73051405037757	bayes_pls_golite062009
protein binding	0.294646489785198	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: