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View Structure Prediction Details

Protein: HPPK_STRP6
Organism: Streptococcus pyogenes MGAS10394
Length: 166 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HPPK_STRP6.

Description E-value Query
Range
Subject
Range
gi|24377344, gi|... - gi|24379413|ref|NP_721368.1| putative 2-amino-4-hydroxy-6-hydroxymethylpteridine pyrophosphokinase [...
gi|254997475 - gi|254997475|dbj|BAH88076.1| putative 2-amino-4-hydroxy-6- hydroxymethylpteridine pyrophosphokinase ...
229.0 [0..1] [159..1]

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Predicted Domain #1
Region A:
Residues: [1-166]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTIVYLSLGT NMGDRAAYLQ KALEALADLP QTRLLAQSSI YETTAWGKTG QADFLNMACQ  60
   61 LDTQLTAADF LKETQAIEQS LGRVRHEKWG SRTIDIDILL FGEEVYDTKE LKVPHPYMTE 120
  121 RAFVLIPLLE LQSDLKLPPN HKFLRDYLAA LDQSDITLFS AQQTEF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.522879
Match: 1dy3A
Description: 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity 5.95418117400583 bayes_pls_golite062009
diphosphotransferase activity 4.79017391246148 bayes_pls_golite062009
catalytic activity 2.44295736158702 bayes_pls_golite062009
transferase activity 1.5312510694044 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.34283740138285 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle