YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|49187478, gi\|...
Organism:	Bacillus anthracis str. Sterne
Length:	587 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|49187478, gi|....

Description	E-value	Query Range	Subject Range
gi\|51974390, gi\|... - gi\|52140921\|ref\|YP_085908.1\| phosphate regulon sensor protein [Bacillus cereus E33L], gi\|51974390\|gb...	7.0E-97	[1..587]	[1..587]
gi\|47557784, gi\|... - gi\|47564998\|ref\|ZP_00236041.1\| sensory box histidine kinase PhoR [Bacillus cereus G9241], gi\|4755778...	8.0E-97	[1..587]	[1..587]
gi\|42783765, gi\|... - gi\|42783765\|ref\|NP_981012.1\| sensory box histidine kinase PhoR [Bacillus cereus ATCC 10987], gi\|4273...	2.0E-96	[1..587]	[1..587]
gi\|30264658, gi\|... - gi\|30264658\|ref\|NP_847035.1\| sensory box histidine kinase PhoR [Bacillus anthracis str. Ames], gi\|30... gi\|65321955, gi\|... - gi\|65321955\|ref\|ZP_00394914.1\| COG0642: Signal transduction histidine kinase [Bacillus anthracis str... gi\|165869708, gi... - gi\|165869708\|ref\|ZP_02214366.1\| sensory box histidine kinase PhoR [Bacillus anthracis str. A0488], g... gi\|167530779, gi... - gi\|167633978\|ref\|ZP_02392301.1\| sensory box histidine kinase PhoR [Bacillus anthracis str. A0442], g... gi\|167513830, gi... - gi\|167638013\|ref\|ZP_02396291.1\| sensory box histidine kinase PhoR [Bacillus anthracis str. A0193], g... gi\|47530128, gi\|... - gi\|47530128\|ref\|YP_021477.1\| sensory box histidine kinase PhoR [Bacillus anthracis str. 'Ames Ancest... gi\|170685740, gi... - gi\|170685740\|ref\|ZP_02876963.1\| sensory box histidine kinase PhoR [Bacillus anthracis str. A0465], g... gi\|254757502 - gi\|254757502\|ref\|ZP_05209529.1\| sensory box histidine kinase PhoR [Bacillus anthracis str. Australia... gi\|254754670 - gi\|254754670\|ref\|ZP_05206705.1\| sensory box histidine kinase PhoR [Bacillus anthracis str. Vollum] gi\|254741732 - gi\|254741732\|ref\|ZP_05199419.1\| sensory box histidine kinase PhoR [Bacillus anthracis str. Kruger B] gi\|254736695 - gi\|254736695\|ref\|ZP_05194401.1\| sensory box histidine kinase PhoR [Bacillus anthracis str. Western N... gi\|254724958 - gi\|254724958\|ref\|ZP_05186741.1\| sensory box histidine kinase PhoR [Bacillus anthracis str. A1055] gi\|254687395 - gi\|254687395\|ref\|ZP_05151251.1\| sensory box histidine kinase PhoR [Bacillus anthracis str. CNEVA-906... gi\|229264805, gi... - gi\|229600397\|ref\|YP_002868867.1\| sensory box histidine kinase PhoR [Bacillus anthracis str. A0248], ... gi\|170705359, gi... - gi\|170705359\|ref\|ZP_02895823.1\| sensory box histidine kinase PhoR [Bacillus anthracis str. A0389], g... gi\|227004296, gi... - gi\|227817372\|ref\|YP_002817381.1\| sensory box histidine kinase PhoR [Bacillus anthracis str. CDC 684]... gi\|177651147, gi... - gi\|177651147\|ref\|ZP_02933978.1\| sensory box histidine kinase PhoR [Bacillus anthracis str. A0174], g... gi\|190559871, gi... - gi\|190569089\|ref\|ZP_03021989.1\| sensory box histidine kinase PhoR [Bacillus anthracis Tsiankovskii-I... gi\|196032783, gi... - gi\|196032783\|ref\|ZP_03100196.1\| sensory box histidine kinase PhoR [Bacillus cereus W], gi\|195994212\|... gi\|218905815, gi... - gi\|218905815\|ref\|YP_002453649.1\| sensory box histidine kinase PhoR [Bacillus cereus AH820], gi\|21854...	2.0E-96	[1..587]	[1..587]
gi\|49330250, gi\|... - gi\|49478694\|ref\|YP_038633.1\| phosphate regulon sensor protein [Bacillus thuringiensis serovar konkuk...	3.0E-96	[1..587]	[1..587]
gi\|89154470, gi\|... - gi\|89207576\|ref\|ZP_01186114.1\| PAS [Bacillus weihenstephanensis KBAB4], gi\|89154470\|gb\|EAR74501.1\| P...	1.0E-95	[1..587]	[1..587]
gi\|30022663, gi\|... - gi\|30022663\|ref\|NP_834294.1\| phosphate regulon sensor protein phoR [Bacillus cereus ATCC 14579], gi\|...	6.0E-95	[1..587]	[1..587]
gi\|74490501, gi\|... - gi\|75762015\|ref\|ZP_00741929.1\| Phosphate regulon sensor protein phoR [Bacillus thuringiensis serovar... gi\|218899741, gi... - gi\|218899741\|ref\|YP_002448152.1\| sensory box histidine kinase PhoR [Bacillus cereus G9842], gi\|21854...	7.0E-95	[1..587]	[1..587]
gi\|152025722, gi... - gi\|89201565\|ref\|ZP_01180303.1\| PAS [Bacillus cereus subsp. cytotoxis NVH 391-98], gi\|89150351\|gb\|EAR...	8.0E-89	[1..582]	[1..582]
gi\|221315177 - gi\|221315177\|ref\|ZP_03596982.1\| two-component sensor histidine kinase [Bacillus subtilis subsp. subt... gi\|221320094 - gi\|221320094\|ref\|ZP_03601388.1\| two-component sensor histidine kinase [Bacillus subtilis subsp. subt... gi\|221324376 - gi\|221324376\|ref\|ZP_03605670.1\| two-component sensor histidine kinase [Bacillus subtilis subsp. subt... PHOR_BACSU - Alkaline phosphatase synthesis sensor protein phoR OS=Bacillus subtilis GN=phoR PE=1 SV=1 PHOR_BACSU - Alkaline phosphatase synthesis sensor protein PhoR OS=Bacillus subtilis (strain 168) GN=phoR PE=1 SV...	2.0E-82	[1..586]	[1..577]

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Predicted Domain #1

Region A:
Residues: [1-140]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNKFRSRLLF TFVSLIVFIL VGLGLLLETV FENYYIDHAK ERMVKETEYV AVLAEEQGFD  60
   61 DVLKNPYVFE KLEEKIQASI AFVDEKKKVQ YSGGEQSAFS QGIMKELSSE TKKQRNKVIT 120
  121 KEADQNNEFY HAVFVQDVTG

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [141-264]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KQGYILVKST IEPLKDVHQK TWGLLIIGFV IACLVVVFLG MKITGQYIRA IESVTKVAIE  60
   61 LAKGNYKARA YESHSDETGM LSKAINILAR NLQEMTLEQE MQQDRLHTLI ENMGSGMILI 120
  121 DSRG

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	3.72
Match:	2f95B
Description:	M intermediate structure of sensory rhodopsin II/transducer complex in combination with the ground state structure
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [265-336]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YINLVNRSYK ETFHVTDEEY LDRLYYESFH HTEIIELVEE IFMTEVKVRK QMLLPLGIER  60
   61 KHFEVYGAPI IG

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.829	0.985	two-component sensor activity	d.110.3	PYP-like sensor domain (PAS domain)

Predicted Domain #4

Region A:
Residues: [337-587]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TNHEWKGIVL VFHDITELKK LEQMRKDFLA NVSHELKTPI TSIKGFSETL LDGAMDNKKF  60
   61 CEHFLHIILK ESERMQGLIE DLLDLSKIEQ QGFKLSMGTV DMKGLLEDIH MVLDNKAGEK 120
  121 EISLQVNTLK RVSVIGDPSR LQQIFINLMN NAIVYTPAGG VVSVELAEDK YNAYIKVSDT 180
  181 GIGISKDEIP RIFERFYRVD KARSRNTGGT GLGLSIVKHL VEAHHGTITV DSEVGEGTTF 240
  241 TVVLPKSATE K

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	48.09691
Match:	2c2aA
Description:	Structure of the entire cytoplasmic portion of a sensor histidine kinase protein
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits