YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30264419, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	461 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30264419, gi|....

Description	E-value	Query Range	Subject Range
gi\|49478615, gi\|... - gi\|49478615\|ref\|YP_038400.1\| alkaline phosphatase [Bacillus thuringiensis serovar konkukian str. 97-...	0.0	[1..461]	[1..461]
gi\|47569342, gi\|... - gi\|47569342\|ref\|ZP_00240026.1\| alkaline phosphatase [Bacillus cereus G9241], gi\|47554013\|gb\|EAL12380... gi\|229157961, gi... - gi\|229157961\|ref\|ZP_04286033.1\| Alkaline phosphatase 3 [Bacillus cereus ATCC 4342], gi\|228625521\|gb\|...	0.0	[1..461]	[1..461]
gi\|163942099, gi... - gi\|89206310\|ref\|ZP_01184870.1\| Alkaline phosphatase [Bacillus weihenstephanensis KBAB4], gi\|89155735... gi\|229013564, gi... - gi\|229013564\|ref\|ZP_04170697.1\| Alkaline phosphatase 3 [Bacillus mycoides DSM 2048], gi\|228747724\|gb...	0.0	[1..461]	[1..461]
gi\|228653744, gi... - gi\|229129627\|ref\|ZP_04258595.1\| Alkaline phosphatase 3 [Bacillus cereus BDRD-Cer4], gi\|228653744\|gb\|... gi\|228836477, gi... - gi\|228923098\|ref\|ZP_04086389.1\| Alkaline phosphatase 3 [Bacillus thuringiensis serovar huazhongensis... gi\|218235966, gi... - gi\|218235966\|ref\|YP_002369156.1\| alkaline phosphatase [Bacillus cereus B4264], gi\|218163923\|gb\|ACK63... gi\|30022424, gi\|... - gi\|30022424\|ref\|NP_834055.1\| alkaline phosphatase [Bacillus cereus ATCC 14579], gi\|29897982\|gb\|AAP11...	0.0	[1..461]	[1..461]
gi\|42739402, gi\|... - gi\|42783473\|ref\|NP_980720.1\| alkaline phosphatase [Bacillus cereus ATCC 10987], gi\|42739402\|gb\|AAS43...	0.0	[1..461]	[1..461]
gi\|51974626, gi\|... - gi\|52141157\|ref\|YP_085672.1\| alkaline phosphatase [Bacillus cereus E33L], gi\|51974626\|gb\|AAU16176.1\|...	0.0	[1..461]	[1..461]
gi\|152976773, gi... - gi\|89201407\|ref\|ZP_01180148.1\| Alkaline phosphatase [Bacillus cereus subsp. cytotoxis NVH 391-98], g...	0.0	[1..461]	[1..461]
gi\|11276057 - gi\|11276057\|gb\|AAG33874.1\|AF320303_1 alkaline phosphatase [Lactobacillus delbrueckii subsp. bulgaric...	0.0	[2..461]	[12..471]
gi\|108998962 - gi\|108998962\|ref\|XP_001109717.1\| PREDICTED: tissue non-specific alkaline phosphatase [Macaca mulatta...	0.0	[5..454]	[127..619]
gi\|62089214 - gi\|62089214\|dbj\|BAD93051.1\| ALPL protein variant [Homo sapiens]	0.0	[5..454]	[77..569]

Back

Predicted Domain #1

Region A:
Residues: [1-461]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKFVKKAWP FAVVASLAVT SVATWNFTRS SEVSADENGS NAKIKNVIVL IGDGMGPSYM  60
   61 TAHRYMKDNP KTFEMESTEF DKHLVGTQKT YPEDEHENIT DSASAATAMS AGIKTYNAAI 120
  121 AVDNDKAEVK TVLEQAKEKG KSTGLVATSE ITHATPAAFG AHDISRKSMD AIANDYFDEK 180
  181 IKGKHKVDVM LGGGVKNFVR KDRNLTEEFK KSGYSYVTDR DQLLNDKNDQ ILGLFAPGGL 240
  241 DKMIDRNEKT PSLEEMTNAA IERLNKNKKG FFLMVEGSQI DWAGHDNDIV GAMSEMEDFE 300
  301 KAFKAAIEFA KKDKNTLVIA TADHATGGLS LGANGEYNFK VDPIKAAKRT PDFMANEIVK 360
  361 GANVEETLKK YIDLQLTPEE IKAVNDIAPS KDVTKIDNAI EDIFNKRSVT GWTTGGHTGE 420
  421 DVNVYAFGPG KYLFSGVQEN TNLAKRVFDI VGGGDPNKGR R

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	126.0
Match:	1zebA
Description:	X-ray structure of alkaline phosphatase from human placenta in complex with 5'-AMP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrolase activity, acting on ester bonds	2.8318172470006	bayes_pls_golite062009
catalytic activity	2.31328968099128	bayes_pls_golite062009
phosphatase activity	1.51067400873904	bayes_pls_golite062009
phosphoric ester hydrolase activity	1.32325931665891	bayes_pls_golite062009
hydrolase activity	1.00893121506608	bayes_pls_golite062009
alkaline phosphatase activity	0.688134376880261	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.515209766971615	bayes_pls_golite062009
kinase activity	0.503509300116176	bayes_pls_golite062009
binding	0.48922825585019	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.356909797780746	bayes_pls_golite062009
protein binding	0.208332656410563	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: