YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30258132, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	502 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30258132, gi|....

Description	E-value	Query Range	Subject Range
ARLY_NITOC - Argininosuccinate lyase OS=Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848) GN=argH PE=3 SV=1 gi\|207089381 - gi\|207089381\|gb\|EDZ66653.1\| argininosuccinate lyase [Nitrosococcus oceani AFC27] gi\|254436270, gi... - gi\|254436270\|ref\|ZP_05049777.1\| argininosuccinate lyase [Nitrosococcus oceani AFC27], gi\|224409727\|r...	0.0	[1..471]	[1..463]
gi\|148545463, gi... - gi\|82737852\|ref\|ZP_00900696.1\| Argininosuccinate lyase [Pseudomonas putida F1], gi\|82715091\|gb\|EAP50...	0.0	[1..474]	[32..499]
ARLY_PSESM - Argininosuccinate lyase OS=Pseudomonas syringae pv. tomato (strain DC3000) GN=argH PE=3 SV=1 ARLY_PSESM - Argininosuccinate lyase OS=Pseudomonas syringae pv. tomato GN=argH PE=3 SV=1	0.0	[3..472]	[1..462]
ARLY_PSEE4 - Argininosuccinate lyase OS=Pseudomonas entomophila (strain L48) GN=argH PE=3 SV=1 gi\|95113244 - gi\|95113244\|emb\|CAK17972.1\| argininosuccinate lyase (Arginosuccinase) (ASAL) [Pseudomonas entomophil...	0.0	[3..474]	[1..464]
ARLY_PSE14 - Argininosuccinate lyase OS=Pseudomonas savastanoi pv. phaseolicola (strain 1448A / Race 6) GN=argH P...	0.0	[3..472]	[1..462]
ARLY_PSEPK - Argininosuccinate lyase OS=Pseudomonas putida (strain KT2440) GN=argH PE=3 SV=2	0.0	[3..474]	[1..464]
gi\|84317867, gi\|... - gi\|84317867\|ref\|ZP_00966302.1\| COG0165: Argininosuccinate lyase [Pseudomonas aeruginosa C3719], gi\|2... ARLY_PSEAE - Argininosuccinate lyase OS=Pseudomonas aeruginosa GN=argH PE=3 SV=2 ARLY_PSEAE - Argininosuccinate lyase OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 122...	0.0	[6..474]	[4..464]
gi\|107104365 - gi\|107104365\|ref\|ZP_01368283.1\| hypothetical protein PaerPA_01005440 [Pseudomonas aeruginosa PACS2]	0.0	[6..474]	[4..464]
ARLY_SACD2 - Argininosuccinate lyase OS=Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) GN=argH P...	0.0	[1..476]	[1..469]

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Predicted Domain #1

Region A:
Residues: [1-502]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKQSKEEFIK SEGADFPGKT YVDCVLQHVF DFQRNYLLKD MFQVHKAHIV MLTEENLMKK  60
   61 EEAKFILHAL KKVEEIPEEQ LLYTEQHEDL FFLVEHLISQ EAKSDFVSNM HIGRSRNDMG 120
  121 VTMYRMSLRR YVLRLMEHHL LLQESILQLA ADHKETIMPA YTHTQPAQPT TFGHYTLAIY 180
  181 DTMQRDLERM KKTYKLLNQS PMGAAALSTT SFPIKRERVA DLLGFTNVIE NSYDAVAGAD 240
  241 YLLEVSSLLM IMMTNTSRWI HDFLLLATKE YDGIAVARPY VQISSIMPQK RNPVSIEHAR 300
  301 AITSSAPGEA FTVFQMIHNT PFGEIVDTED DLQPYLYKGI EKAIRVFCIL NAVIRTMKVE 360
  361 EDTLKRRSYK HAITITDFAD VLTKNYGIPF RHAHHAASVI ANMSLEQKKE LHELCFKDVN 420
  421 IYLQEKFKIQ LLEKEWEEII SPEAFIQKRN VYGGPSKKEM ERMINNRKEL FRKEEEVFEE 480
  481 EKQRILQAEN DLNMLASNII ES

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	122.0
Match:	1tj7A
Description:	Structure determination and refinement at 2.44 A resolution of Argininosuccinate lyase from E. coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
amidine-lyase activity	3.84281419858187	bayes_pls_golite062009
argininosuccinate lyase activity	3.58328346705456	bayes_pls_golite062009
catalytic activity	2.51282259572665	bayes_pls_golite062009
lyase activity	2.31268471569846	bayes_pls_golite062009
carbon-nitrogen lyase activity	2.2046475419807	bayes_pls_golite062009
binding	0.616567403608599	bayes_pls_golite062009
ammonia-lyase activity	0.491229595527877	bayes_pls_golite062009
protein binding	0.110986062813054	bayes_pls_golite062009
fumarate hydratase activity	0.0801096514904147	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: