YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30261999, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	297 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30261999, gi|....

Description	E-value	Query Range	Subject Range
KHSE_BACCZ - Homoserine kinase OS=Bacillus cereus (strain ZK / E33L) GN=thrB PE=3 SV=1	7.0E-65	[1..297]	[1..297]
KHSE_BACHK - Homoserine kinase OS=Bacillus thuringiensis subsp. konkukian GN=thrB PE=3 SV=1 gi\|254721322 - gi\|254721322\|ref\|ZP_05183112.1\| homoserine kinase [Bacillus anthracis str. A1055] KHSE_BACC0 - Homoserine kinase OS=Bacillus cereus (strain AH820) GN=thrB PE=3 SV=1 KHSE_BACHK - Homoserine kinase OS=Bacillus thuringiensis subsp. konkukian (strain 97-27) GN=thrB PE=3 SV=1 gi\|195990432, gi... - gi\|196036959\|ref\|ZP_03104336.1\| homoserine kinase [Bacillus cereus W], gi\|195990432\|gb\|EDX54423.1\| h...	1.0E-64	[1..297]	[1..297]
gi\|74489438, gi\|... - gi\|75763073\|ref\|ZP_00742857.1\| Homoserine kinase [Bacillus thuringiensis serovar israelensis ATCC 35...	2.0E-64	[1..297]	[1..297]
KHSE_BACWK - Homoserine kinase OS=Bacillus weihenstephanensis (strain KBAB4) GN=thrB PE=3 SV=1	4.0E-64	[1..297]	[1..297]
KHSE_BACCR - Homoserine kinase OS=Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 937...	4.0E-64	[1..296]	[1..296]
gi\|47570003, gi\|... - gi\|47570003\|ref\|ZP_00240666.1\| homoserine kinase [Bacillus cereus G9241], gi\|47553351\|gb\|EAL11739.1\|...	7.0E-64	[1..297]	[1..297]
KHSE_BACC1 - Homoserine kinase OS=Bacillus cereus (strain ATCC 10987 / NRS 248) GN=thrB PE=3 SV=1	7.0E-64	[1..297]	[1..297]
gi\|89203811, gi\|... - gi\|89203811\|ref\|ZP_01182394.1\| Homoserine kinase [Bacillus cereus subsp. cytotoxis NVH 391-98], gi\|8...	1.0E-59	[1..289]	[1..289]
gi\|227553950, gi... - gi\|227553950\|ref\|ZP_03983997.1\| homoserine kinase [Enterococcus faecalis HH22], gi\|227176936\|gb\|EEI5... KHSE_ENTFA - Homoserine kinase OS=Enterococcus faecalis (strain ATCC 700802 / V583) GN=thrB PE=3 SV=1 KHSE_ENTFA - Homoserine kinase OS=Enterococcus faecalis GN=thrB PE=3 SV=1	3.0E-58	[4..289]	[1..286]
KHSE_ECOLI - Homoserine kinase (EC 2.7.1.39) (HSK) (HK) - Escherichia coli EG10999 - homoserine kinase / Homoserine kinase KHSE_ECOBW - Homoserine kinase OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=thrB PE=3 SV=1 EG10999 - homoserine kinase / Homoserine kinase gi\|89106887, gi\|... - gi\|89106887\|ref\|AP_000667.1\| homoserine kinase [Escherichia coli str. K-12 substr. W3110], gi\|856742... gi\|83585311, gi\|... - gi\|83585311\|ref\|ZP_00923959.1\| COG0083: Homoserine kinase [Escherichia coli 101-1], gi\|194439274\|ref... KHSE_ECODH - Homoserine kinase OS=Escherichia coli (strain K12 / DH10B) GN=thrB PE=3 SV=1	1.0E-57	[3..291]	[1..309]

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Predicted Domain #1

Region A:
Residues: [1-297]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIPLSIRVPA STANVGPGFD SVGIALSLYL HVVVKEKSDK WQVIHSFEDS IPTDDKNLIV  60
   61 STACKVCPSL SPHIIEVTSN IPLTRGLGSS ASAIVAGIEL ANQLGKLNLT IDQKVQIATN 120
  121 FEGHPDNVAA SILGGTVIGA LDGKNVSVVR IESKELGVIS LIPNEELNTD ESRSVLPDVF 180
  181 PFHEAVKASA ISNVLVAALC QKKWKVVGEM MERDHFHEPY RLELVPLLPS IRKCAKEFGA 240
  241 YGTALSGAGP SIFILTPYEK RQEIAEQLAR VFTSMKVCEL EIDHRGITVN KKEHIGL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	39.0
Match:	1fwkA
Description:	Homoserine kinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.836142537655721	bayes_pls_golite062009
structural constituent of ribosome	0.0246382239358082	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: