YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30256120, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	335 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30256120, gi|....

Description	E-value	Query Range	Subject Range
ILVC_ALKEH - Ketol-acid reductoisomerase OS=Alkalilimnicola ehrlichii (strain ATCC BAA-1101 / DSM 17681 / MLHE-1)...	0.0	[1..335]	[1..336]
ILVC_GEOMG - Ketol-acid reductoisomerase OS=Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210) GN=i...	0.0	[1..334]	[1..335]
ILVC_GEOSL - Ketol-acid reductoisomerase OS=Geobacter sulfurreducens GN=ilvC PE=3 SV=1 ILVC_GEOSL - Ketol-acid reductoisomerase OS=Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA) GN=ilv...	0.0	[1..334]	[1..335]
ILVC_CUPPJ - Ketol-acid reductoisomerase OS=Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) GN=ilvC PE=3 S...	0.0	[1..334]	[1..335]
ILVC_RHORT - Ketol-acid reductoisomerase OS=Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG ... gi\|48763492 - ref\|ZP_00268047.1\| COG0059: Ketol-acid reductoisomerase [Rhodospirillum rubrum]	0.0	[1..335]	[1..337]
sp\|A0L626\|ILVC_MAGMM - Ketol-acid reductoisomerase OS=Magnetococcus marinus (strain ATCC BAA-1437 / JCM 17883 / MC-1) GN=il... ILVC_MAGMM - Ketol-acid reductoisomerase OS=Magnetococcus marinus (strain ATCC BAA-1437 / JCM 17883 / MC-1) GN=il...	0.0	[1..334]	[1..335]
ILVC_CUPMC - Ketol-acid reductoisomerase OS=Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507...	0.0	[1..334]	[1..335]
ILVC_RALSO - Ketol-acid reductoisomerase OS=Ralstonia solanacearum (strain GMI1000) GN=ilvC PE=3 SV=1 ILVC_RALSO - Ketol-acid reductoisomerase OS=Ralstonia solanacearum GN=ilvC PE=3 SV=1	0.0	[1..334]	[1..335]
gi\|207723861, gi... - gi\|207723861\|ref\|YP_002254259.1\| ketol-acid reductoisomerase (acetohydroxy-acidisomeroreductase) (al... gi\|83746285, gi\|... - gi\|83746285\|ref\|ZP_00943338.1\| Ketol-acid reductoisomerase / 2-dehydropantoate 2-reductase [Ralstoni... gi\|207742721, gi... - gi\|207742721\|ref\|YP_002259113.1\| ketol-acid reductoisomerase (acetohydroxy-acidisomeroreductase) (al...	0.0	[1..334]	[1..335]
ILVC_POLNA - Ketol-acid reductoisomerase OS=Polaromonas naphthalenivorans (strain CJ2) GN=ilvC PE=3 SV=1	0.0	[1..334]	[1..335]

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Predicted Domain #1

Region A:
Residues: [1-335]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTYYEQDAN VGLLQGKTVA VIGYGSQGHA QAQNLRDSGV EVVVGVRPGK SFEVAKADGF  60
   61 EVMSVSEAVR TAQVVQMLLP DEQQAHVYKA EVEENLREGQ MLLFSHGFNI HFGQINPPSY 120
  121 VDVAMVAPKS PGHLVRRVFQ EGNGVPALVA VHQDATGTAL HVALAYAKGV GCTRAGVIET 180
  181 TFQEETETDL FGEQAVLCGG VTALVKAGFE TLTEGGYRPE IAYFECLHEL KLIVDLMYEG 240
  241 GLTNMRHSIS DTAEFGDYVT GSRIVTDETK KEMKRVLTEI QQGEFAKKWI LENQAGRPTY 300
  301 NAMKKAEQNH QLEKVGEELR EMMSWIHAPK ELVKK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	111.0
Match:	1np3A
Description:	Class I ketol-acid reductoisomerase; Class I ketol-acid reductoisomerase (KARI)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.20335378247333	bayes_pls_golite062009
oxidoreductase activity	2.187844467027	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	1.16905220290347	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1.1572935216705	bayes_pls_golite062009
pyrroline-5-carboxylate reductase activity	0.97274261484059	bayes_pls_golite062009
3-hydroxyisobutyrate dehydrogenase activity	0.651029379944751	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: