YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30256046, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	462 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30256046, gi|....

Description	E-value	Query Range	Subject Range
gi\|50736122, gi\|... - gi\|57530433\|ref\|NP_001006382.1\| fumarate hydratase [Gallus gallus], gi\|53130266\|emb\|CAG31462.1\| hypo...	0.0	[3..460]	[47..506]
gi\|49531007, gi\|... - gi\|50085031\|ref\|YP_046541.1\| fumarate hydratase [Acinetobacter sp. ADP1], gi\|49531007\|emb\|CAG68719.1...	0.0	[1..460]	[1..461]
gi\|53692620, gi\|... - gi\|53692620\|ref\|ZP_00122557.2\| COG0114: Fumarase [Haemophilus somnus 129PT], gi\|113461245\|ref\|YP_719...	0.0	[1..459]	[1..461]
FUMC_LEPIN - Fumarate hydratase class II OS=Leptospira interrogans GN=fumC PE=3 SV=1 FUMC_LEPIC - Fumarate hydratase class II OS=Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhag... FUMC_LEPIN - Fumarate hydratase class II OS=Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (str... FUMC_LEPIC - Fumarate hydratase class II OS=Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhag...	0.0	[1..460]	[1..461]
gi\|42522839, gi\|... - gi\|42522839\|ref\|NP_968219.1\| fumarate hydratase [Bdellovibrio bacteriovorus HD100], gi\|39574035\|emb\|...	0.0	[3..460]	[7..464]
gi\|31580769 - gi\|31580769\|gb\|AAP51177.1\| fumarase [Ascaris suum]	0.0	[2..461]	[6..467]
FUMC_PASMU - Fumarate hydratase class II OS=Pasteurella multocida GN=fumC PE=3 SV=1 FUMC_PASMU - Fumarate hydratase class II OS=Pasteurella multocida (strain Pm70) GN=fumC PE=3 SV=1	0.0	[1..459]	[1..461]
gi\|116122205, gi... - gi\|116329461\|ref\|YP_799181.1\| fumarate hydratase [Leptospira borgpetersenii serovar Hardjo-bovis L55... gi\|116123624, gi... - gi\|116329935\|ref\|YP_799653.1\| fumarate hydratase [Leptospira borgpetersenii serovar Hardjo-bovis JB1...	0.0	[1..460]	[1..461]
gi\|108875839, gi... - gi\|157118058\|ref\|XP_001658987.1\| aspartate ammonia lyase [Aedes aegypti], gi\|108875839\|gb\|EAT40064.1...	0.0	[3..461]	[42..503]
gi\|42410098, gi\|... - gi\|42520360\|ref\|NP_966275.1\| fumarate hydratase [Wolbachia endosymbiont of Drosophila melanogaster],...	0.0	[2..460]	[4..463]

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Predicted Domain #1

Region A:
Residues: [1-462]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEYRIERDTL GEIKVPADKL WAAQTQRSKE NFPIGTEQMP LEIVKAFAIL KKSAALSNQK  60
   61 LGKLSEEKAE AIVVAADEII AGKWNEHFPL VVWQTGSGTQ SNMNVNEVIA NRGNQILKEK 120
  121 GSDVHIHPND DVNMSQSSND TFPTALHVAC VLAVENHVLP AITKLKETLA EKVTAFEHII 180
  181 KIGRTHLQDA TPLTLGQEIS GWHRMLEKTE RMIAESNTYM KELAIGGTAV GTGINAHPKF 240
  241 GEMVSEEISQ FTGKQFISAP NKFHALTSHD EVVYTHGALK ALAADLMKIA NDVRWLASGP 300
  301 RSGLGEIIIP ANEPGSSIMP GKVNPTQSEA LTMVVAQVMG NDATIGFAAS QGNFELNVFK 360
  361 PVIAYNFLQS AHLLADAIVS FNDNCAVGIE ADEEIIKENV NRSLMLVTAL NPHIGYENAA 420
  421 KIAKHAHKEG LTLKEAALQS GLLTEEQFNE IVDPKKMIAP KE

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Detection Method:	PSI-BLAST
Confidence:	148.0
Match:	1yfmA
Description:	RECOMBINANT YEAST FUMARASE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
fumarate hydratase activity	4.22589182982073	bayes_pls_golite062009
catalytic activity	2.51282259572665	bayes_pls_golite062009
lyase activity	2.31268471569846	bayes_pls_golite062009
carbon-nitrogen lyase activity	2.2046475419807	bayes_pls_golite062009
histidine ammonia-lyase activity	0.948129236753279	bayes_pls_golite062009
amidine-lyase activity	0.901614580251298	bayes_pls_golite062009
binding	0.854855116369286	bayes_pls_golite062009
argininosuccinate lyase activity	0.617974375213548	bayes_pls_golite062009
ammonia-lyase activity	0.491229595527877	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: