YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|49177569, gi\|...
Organism:	Bacillus anthracis str. Sterne
Length:	463 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|49177569, gi|....

Description	E-value	Query Range	Subject Range
gi\|49331784, gi\|... - gi\|49480228\|ref\|YP_034908.1\| sensor histidine kinase [Bacillus thuringiensis serovar konkukian str. ...	1.0E-85	[1..463]	[1..463]
gi\|47568102, gi\|... - gi\|47568102\|ref\|ZP_00238807.1\| sensory box histidine kinase PhoR, putative [Bacillus cereus G9241], ...	5.0E-85	[1..463]	[1..463]
gi\|228640184, gi... - gi\|229143377\|ref\|ZP_04271808.1\| hypothetical protein bcere0012_5490 [Bacillus cereus BDRD-ST24], gi\|... gi\|228657404, gi... - gi\|229126082\|ref\|ZP_04255104.1\| hypothetical protein bcere0015_5450 [Bacillus cereus BDRD-Cer4], gi\|... gi\|29894376, gi\|... - gi\|30018834\|ref\|NP_830465.1\| two component system histidine kinase [Bacillus cereus ATCC 14579], gi\|...	5.0E-85	[1..463]	[1..463]
gi\|51978130, gi\|... - gi\|52144661\|ref\|YP_082167.1\| sensor histidine kinase [Bacillus cereus E33L], gi\|51978130\|gb\|AAU19680...	6.0E-84	[1..460]	[1..460]
gi\|89155894, gi\|... - gi\|89206170\|ref\|ZP_01184732.1\| ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidi...	4.0E-83	[1..454]	[1..454]
gi\|218540301, gi... - gi\|218848250\|ref\|YP_002455135.1\| sensor histidine kinase [Bacillus cereus AH820], gi\|218540301\|gb\|AC... gi\|229164673, gi... - gi\|229164673\|ref\|ZP_04292537.1\| hypothetical protein bcere0009_53880 [Bacillus cereus R309803], gi\|2... gi\|116585027, gi... - gi\|190015346\|ref\|YP_001967073.1\| sensor histidine kinase [Bacillus cereus], gi\|190015080\|ref\|YP_0019... gi\|44004552, gi\|... - gi\|44004552\|ref\|NP_982221.1\| sensor histidine kinase [Bacillus cereus ATCC 10987], gi\|42741618\|gb\|AA...	1.0E-82	[1..453]	[1..453]
gi\|152974373, gi... - gi\|89203396\|ref\|ZP_01182066.1\| ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidi...	2.0E-82	[1..459]	[1..459]
gi\|74490416, gi\|... - gi\|75762098\|ref\|ZP_00742003.1\| Two component system histidine kinase [Bacillus thuringiensis serovar...	2.0E-82	[8..463]	[17..472]
gi\|20808918 - gi\|20808918\|ref\|NP_624089.1\| Sensory transduction histidine kinase [Thermoanaerobacter tengcongensis... gi\|20808918, gi\|... - gi\|20808918\|ref\|NP_624089.1\| sensory transduction histidine kinase [Thermoanaerobacter tengcongensis...	2.0E-74	[1..457]	[1..468]

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Predicted Domain #1

Region A:
Residues: [1-134]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKRISIQFGF YFLIVTLLIE SVLFVLLYYS LVNTRVNEEM TALLKRGNSH RDVLEKYYDE  60
   61 QTISHVALME SEAETTVVIT NTNKEVLAKS NKINTTIKNH ISSMQTRTNH DGAIIENHWK 120
  121 TSNYICTVSP IIVA

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [135-209]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKHEGYVYMF LGTESIEKLV NGLTKQFIIA GAITFLLTVI TIFLLSRLLT KPLLHMKHAT  60
   61 EKMSKGDLSV SLTTT

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	3.57
Match:	2f95B
Description:	M intermediate structure of sensory rhodopsin II/transducer complex in combination with the ground state structure
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [210-463]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RNDEIGELSS SIQTLANDLH YMKTERSEFL ASVAHELRTP LTYVRGYADI ALKETTSPEQ  60
   61 RLRYLSIIKD ESDYITNLVQ DLFSLAQMEQ HNFSIQVKEV HLHTFLTRIS EKVNAMYKER 120
  121 YITVSFSCPP TLLVNLDEQR FEQVVVNILN NAYRHSKEHS QIHISVIEEN KRISITMEDE 180
  181 GEGIPPEDLP HIFERFYRVD KARSRATGGT GLGLSIVKEI VELHGGNITV TSEVDHGSCF 240
  241 TISLPSIKKH DYHQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	50.522879
Match:	2c2aA
Description:	Structure of the entire cytoplasmic portion of a sensor histidine kinase protein
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits