YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30253911, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	268 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30253911, gi|....

Description	E-value	Query Range	Subject Range
gi\|28211403, gi\|... - gi\|28211403\|ref\|NP_782347.1\| hydroxymethylpyrimidine kinase [Clostridium tetani E88], gi\|28203844\|gb...	5.0E-44	[3..257]	[21..289]
gi\|110802744, gi... - gi\|110802744\|ref\|YP_698658.1\| phosphomethylpyrimidine kinase [Clostridium perfringens SM101], gi\|110...	2.0E-42	[3..248]	[18..264]
gi\|149948927, gi... - gi\|77686688\|ref\|ZP_00802021.1\| Phosphomethylpyrimidine kinase [Alkaliphilus metalliredigenes QYMF], ...	3.0E-42	[3..249]	[15..261]
gi\|106895590, gi... - gi\|158321715\|ref\|YP_001514222.1\| phosphomethylpyrimidine kinase [Alkaliphilus oremlandii OhILAs], gi...	3.0E-42	[3..245]	[15..257]
THIM_METMA - Hydroxyethylthiazole kinase OS=Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / J... THIM_METMA - Hydroxyethylthiazole kinase OS=Methanosarcina mazei GN=thiM PE=3 SV=1	4.0E-42	[10..268]	[5..261]
gi\|20808610 - gi\|20808610\|ref\|NP_623781.1\| Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [Thermoanaerobac... gi\|20808610, gi\|... - gi\|20808610\|ref\|NP_623781.1\| hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [Thermoanaerobac... gi\|214034926, gi... - gi\|254479155\|ref\|ZP_05092505.1\| phosphomethylpyrimidine kinase [Carboxydibrachium pacificum DSM 1265...	6.0E-42	[6..244]	[18..256]
THIM_THEPX - Hydroxyethylthiazole kinase OS=Thermoanaerobacter sp. (strain X514) GN=thiM PE=3 SV=1 gi\|242230983, gi... - gi\|242257481\|ref\|ZP_04802344.1\| Hydroxyethylthiazole kinase [Thermoanaerobacter sp. X513], gi\|242230...	6.0E-42	[10..267]	[6..263]
gi\|110674810, gi... - gi\|110800163\|ref\|YP_695988.1\| phosphomethylpyrimidine kinase [Clostridium perfringens ATCC 13124], g...	8.0E-42	[3..248]	[18..264]
gi\|18145000, gi\|... - gi\|18310320\|ref\|NP_562254.1\| phosphomethylpyrimidine kinase [Clostridium perfringens str. 13], gi\|18...	1.0E-41	[3..248]	[18..264]
gi\|255517037 - gi\|255517037\|ref\|ZP_05384713.1\| putative phosphomethylpyrimidine kinase [Clostridium difficile QCD-9... gi\|255650139 - gi\|255650139\|ref\|ZP_05397041.1\| putative phosphomethylpyrimidine kinase [Clostridium difficile QCD-3... gi\|115250640, gi... - gi\|126699203\|ref\|YP_001088100.1\| putative phosphomethylpyrimidine kinase [Clostridium difficile 630]... gi\|254975231 - gi\|254975231\|ref\|ZP_05271703.1\| putative phosphomethylpyrimidine kinase [Clostridium difficile QCD-6... gi\|255092621 - gi\|255092621\|ref\|ZP_05322099.1\| putative phosphomethylpyrimidine kinase [Clostridium difficile CIP 1... gi\|255100727 - gi\|255100727\|ref\|ZP_05329704.1\| putative phosphomethylpyrimidine kinase [Clostridium difficile QCD-6... gi\|255314358 - gi\|255314358\|ref\|ZP_05355941.1\| putative phosphomethylpyrimidine kinase [Clostridium difficile QCD-7...	1.0E-41	[3..248]	[19..264]

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Predicted Domain #1

Region A:
Residues: [1-268]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNTKEISKVV DLVRESNPLV HNITNVVVTN FTANGLLALG ASPVMAYAKE EVAEMASIAG  60
   61 ALVLNMGTLR PDEVEAMLLA GKSANRNDVP VLFDPVGAGA TSYRTEVARH IPAEIELAII 120
  121 RGNAAEIANV INEKWEIKGV DAGAGNGNVV SIAKQAADEL NTVAVITGKE DVVTDGERTI 180
  181 VIRNGHSILT KITGTGCLLT SVIGAFVAVE KDYVKAAVAA LTFYGVAAEL AAAKTVEKGP 240
  241 GSFQIEFLNQ LANTTSGDIE KYGKIEVI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	35.522879
Match:	1c3qA
Description:	Hydroxyethylthiazole kinase (THZ kinase, ThiK)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phosphomethylpyrimidine kinase activity	4.17236703133163	bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor	2.49796023165143	bayes_pls_golite062009
catalytic activity	2.11518580948187	bayes_pls_golite062009
transferase activity	1.65599843675995	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.53929419091344	bayes_pls_golite062009
kinase activity	1.44909019943198	bayes_pls_golite062009
thiamin-phosphate diphosphorylase activity	1.41576214895876	bayes_pls_golite062009
hydroxyethylthiazole kinase activity	0.44128654727966	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: