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View Structure Prediction Details

Protein: ISPD_GEOSL
Organism: Geobacter sulfurreducens PCA
Length: 232 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ISPD_GEOSL.

Description E-value Query
Range
Subject
Range
gi|1098479 - gi|1098479|gb|AAC37050.1| glucose-1-phosphate thymidyl transferase [Neisseria meningitidis]
176.0 [0..2] [228..13]
gi|33637041 - gi|33637041|gb|AAQ23679.1| glucose-1-phosphate thymidyltransferase [Geobacillus stearothermophilus]
174.0 [0..3] [227..1]
gi|45250012 - gi|45250012|gb|AAS55725.1| glucose-1-phosphate thymidyltransferase [Aneurinibacillus thermoaerophilu...
174.0 [0..3] [228..1]
gi|11261719 - pir||B81240 glucose-1-phosphate thymidylyltransferase NMB0080, NMB0062 [imported] - Neisseria mening...
RMLA_NEIMB - Glucose-1-phosphate thymidylyltransferase OS=Neisseria meningitidis serogroup B (strain MC58) GN=rml...
RMLA_NEIMB - Glucose-1-phosphate thymidylyltransferase OS=Neisseria meningitidis serogroup B GN=rmlA1 PE=3 SV=2
174.0 [0..3] [228..1]
gi|34811708, gi|... - gi|34811708|pdb|1H5S|B Chain B, Thymidylyltransferase Complexed With Tmp, gi|21466153|pdb|1H5T|B Cha...
173.0 [0..1] [228..1]
gi|68196230, gi|... - gi|69244639|ref|ZP_00602903.1| Glucose-1-phosphate thymidylyltransferase, long form [Enterococcus fa...
gi|48826109 - ref|ZP_00287334.1| COG1209: dTDP-glucose pyrophosphorylase [Enterococcus faecium]
173.0 [0..3] [227..1]
gi|56459651, gi|... - gi|56459651|ref|YP_154932.1| dTDP-glucose pyrophosphorylase [Idiomarina loihiensis L2TR], gi|5617866...
173.0 [0..3] [227..1]
gi|71906877, gi|... - gi|71906877|ref|YP_284464.1| glucose-1-phosphate thymidylyltransferase [Dechloromonas aromatica RCB]...
173.0 [0..4] [228..6]

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Predicted Domain #1
Region A:
Residues: [1-232]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVFALVPAA GMGKRMGASI NKQYLILAGR PILAHTLSVF EGASFVDGIF VITPEDEIPF  60
   61 CRDHVVERYG FTKVRGIVAG GAERQHSVLN GLRAMEGTVA DDDVILIHDG VRPFVSTDVL 120
  121 ARATAVARED DGALVAVPAK DTVKTVEDGI ITGTPPRETL WLAQTPQAFR YAVIRAAHEI 180
  181 ADAERFLGTD DAMLVERLGR SVRIVVGDYR NIKITTPEDM VLAEAFLKEL AA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.0
Match: 1vgtA
Description: Crystal structure of 4-diphosphocytidyl-2C-methyl-D-erythritol synthase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity 2.01680144494637 bayes_pls_golite062009
catalytic activity 1.88676710996045 bayes_pls_golite062009
transferase activity 1.47184463413038 bayes_pls_golite062009
nucleotidyltransferase activity 1.03393419806381 bayes_pls_golite062009
cytidylyltransferase activity 0.983416157001861 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 0.651454753851031 bayes_pls_golite062009
UDP-glycosyltransferase activity 0.423789091098118 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.361674579616957 bayes_pls_golite062009

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